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Mechanisms of Cytochrome P450-Catalyzed Oxidations

ACS catalysis, 2018-12, Vol.8 (12), p.10964-10976

Guengerich, F. Peter

2018

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Survey of Human Oxidoreductases and Cytochrome P450 Enzymes Involved in the Metabolism of Xenobiotic and Natural Chemicals

Chemical research in toxicology, 2015-01, Vol.28 (1), p.38-42

2015

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Formation and Cleavage of C–C Bonds by Enzymatic Oxidation–Reduction Reactions

Chemical reviews, 2018-07, Vol.118 (14), p.6573-6655

2018

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Cytochrome P450 research and The Journal of Biological Chemistry

The Journal of biological chemistry, 2019-02, Vol.294 (5), p.1671-1680

Guengerich, F. Peter

2019

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Drug Metabolism: A Half-Century Plus of Progress, Continued Needs, and New Opportunities

Drug metabolism and disposition, 2023-01, Vol.51 (1), p.99-104

Guengerich, F Peter

2023

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Recent Structural Insights into Cytochrome P450 Function

Trends in pharmacological sciences (Regular ed.), 2016-08, Vol.37 (8), p.625-640

2016

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A history of the roles of cytochrome P450 enzymes in the toxicity of drugs

한국독성학회지, 2021, 37(1), , pp.1-23

Guengerich, F. Peter

2021

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Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development

DRUG METABOLISM AND PHARMACOKINETICS, 2011-01, Vol.26 (1), p.3-14

Guengerich, F. Peter

2011

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Contributions of Human Enzymes in Carcinogen Metabolism

Chemical research in toxicology, 2012-07, Vol.25 (7), p.1316-1383

2012

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Introduction to Metals in Biology 2018: Copper homeostasis and utilization in redox enzymes

The Journal of biological chemistry, 2018-03, Vol.293 (13), p.4603-4605

Guengerich, F. Peter

2018

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Unusual Cytochrome P450 Enzymes and Reactions

The Journal of biological chemistry, 2013-06, Vol.288 (24), p.17065-17073

2013

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Human Family 1–4 cytochrome P450 enzymes involved in the metabolic activation of xenobiotic and physiological chemicals: an update

Archives of toxicology, 2021-02, Vol.95 (2), p.395-472

2021

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The relationships between cytochromes P450 and H2O2: Production, reaction, and inhibition

Journal of inorganic biochemistry, 2018-09, Vol.186, p.228-234

2018

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Inhibition of Cytochrome P450 Enzymes by Drugs-Molecular Basis and Practical Applications

Biomolecules & Therapeutics, 2022, 30(1), , pp.1-18

Guengerich, F Peter

2022

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Mechanism of the Third Oxidative Step in the Conversion of Androgens to Estrogens by Cytochrome P450 19A1 Steroid Aromatase

Journal of the American Chemical Society, 2014-10, Vol.136 (42), p.15016-15025

2014

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Roles of Cytochrome P450 in Metabolism of Ethanol and Carcinogens

Advances in experimental medicine and biology, 2018-01, Vol.1032, p.15-35

2018

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Structural analyses of Candida albicans sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis

The Journal of biological chemistry, 2017-04, Vol.292 (16), p.6728-6743

2017

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Plasma oxysterol levels in luminal subtype breast cancer patients are associated with clinical data

The Journal of steroid biochemistry and molecular biology, 2020-03, Vol.197, p.105566-105566, Article 105566

2020

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Kinetic Modeling of Steady-State Situations in Cytochrome P450 Enzyme Reactions

Drug metabolism and disposition, 2019-11, Vol.47 (11), p.1232-1239

Guengerich, F Peter

2019

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A requirement for an active proton delivery network supports a compound I-mediated C–C bond cleavage in CYP51 catalysis

The Journal of biological chemistry, 2020-07, Vol.295 (29), p.9998-10007

2020

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Orphans in the human cytochrome P450 superfamily: approaches to discovering functions and relevance in pharmacology

Pharmacological reviews, 2011-09, Vol.63 (3), p.684-699

2011

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Effects of 7-ketocholesterol on tamoxifen efficacy in breast carcinoma cell line models in vitro

The Journal of steroid biochemistry and molecular biology, 2023-09, Vol.232, p.106354-106354, Article 106354

2023

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Tight binding of cytochrome b5 to cytochrome P450 17A1 is a critical feature of stimulation of C21 steroid lyase activity and androgen synthesis

The Journal of biological chemistry, 2021-01, Vol.296, p.100571-100571, Article 100571

2021

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Cytochrome P450s and other enzymes in drug metabolism and toxicity

The AAPS journal, 2006-03, Vol.8 (1), p.E101-E111

Guengerich, F Peter

2006

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Cyp27c1 Red-Shifts the Spectral Sensitivity of Photoreceptors by Converting Vitamin A1 into A2

Current biology, 2015-12, Vol.25 (23), p.3048-3057

2015

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Mechanisms of Cytochrome P450-Catalyzed Oxidations

Survey of Human Oxidoreductases and Cytochrome P450 Enzymes Involved in the Metabolism of Xenobiotic and Natural Chemicals

Formation and Cleavage of C–C Bonds by Enzymatic Oxidation–Reduction Reactions

Cytochrome P450 research and The Journal of Biological Chemistry

Drug Metabolism: A Half-Century Plus of Progress, Continued Needs, and New Opportunities

Recent Structural Insights into Cytochrome P450 Function

A history of the roles of cytochrome P450 enzymes in the toxicity of drugs

Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development

Contributions of Human Enzymes in Carcinogen Metabolism

Introduction to Metals in Biology 2018: Copper homeostasis and utilization in redox enzymes

Unusual Cytochrome P450 Enzymes and Reactions

Human Family 1–4 cytochrome P450 enzymes involved in the metabolic activation of xenobiotic and physiological chemicals: an update

The relationships between cytochromes P450 and H2O2: Production, reaction, and inhibition

Inhibition of Cytochrome P450 Enzymes by Drugs-Molecular Basis and Practical Applications

Mechanism of the Third Oxidative Step in the Conversion of Androgens to Estrogens by Cytochrome P450 19A1 Steroid Aromatase

Roles of Cytochrome P450 in Metabolism of Ethanol and Carcinogens

Structural analyses of Candida albicans sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis

Plasma oxysterol levels in luminal subtype breast cancer patients are associated with clinical data

Kinetic Modeling of Steady-State Situations in Cytochrome P450 Enzyme Reactions

A requirement for an active proton delivery network supports a compound I-mediated C–C bond cleavage in CYP51 catalysis

Orphans in the human cytochrome P450 superfamily: approaches to discovering functions and relevance in pharmacology

Effects of 7-ketocholesterol on tamoxifen efficacy in breast carcinoma cell line models in vitro

Tight binding of cytochrome b5 to cytochrome P450 17A1 is a critical feature of stimulation of C21 steroid lyase activity and androgen synthesis

Cytochrome P450s and other enzymes in drug metabolism and toxicity

Cyp27c1 Red-Shifts the Spectral Sensitivity of Photoreceptors by Converting Vitamin A1 into A2

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