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Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease

Cell stem cell, 2014-11, Vol.15 (5), p.653-665

2014

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MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates

Nature communications, 2019-09, Vol.10 (1), p.4357-12, Article 4357

2019

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Propagation of α-Synuclein Strains within Human Reconstructed Neuronal Network

Stem cell reports, 2019-02, Vol.12 (2), p.230-244

2019

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Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines

Current stem cell reports, 2018-11, Vol.11 (5), p.1199-1210

2018

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Modeling and Targeting Neuroglial Interactions with Human Pluripotent Stem Cell Models

International journal of molecular sciences, 2022-01, Vol.23 (3), p.1684

2022

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Allele-specific silencing of mutant huntingtin in rodent brain and human stem cells

PloS one, 2014-06, Vol.9 (6), p.e99341-e99341

2014

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Huntingtin lowering impairs the maturation and synchronized synaptic activity of human cortical neuronal networks derived from induced pluripotent stem cells

Neurobiology of disease, 2024-10, Vol.200, p.106630, Article 106630

2024

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The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes

Cell reports (Cambridge), 2017-09, Vol.20 (12), p.2980-2991

2017

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Translating cell therapies for neurodegenerative diseases: Huntington's disease as a model disorder

Brain (London, England : 1878), 2022-06, Vol.145 (5), p.1584-1597

2022

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Longitudinal characterization of cognitive and motor deficits in an excitotoxic lesion model of striatal dysfunction in non-human primates

Neurobiology of disease, 2019-10, Vol.130, p.104484-104484, Article 104484

2019

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Derivation of Midbrain Dopamine Neurons from Human Embryonic Stem Cells

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (34), p.12543-12548

2004

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Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice

Science advances, 2021-03, Vol.7 (14)

2021

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Embryonic stem cells neural differentiation qualifies the role of Wnt/β‐Catenin signals in human telencephalic specification and regionalization

Stem cells (Dayton, Ohio), 2013-09, Vol.31 (9), p.1763-1774

2013

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Cell Therapy for Huntington's Disease: Learning from Failure

Movement disorders, 2021-03, Vol.36 (3), p.787-788

2021

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CTIP2-Regulated Reduction in PKA-Dependent DARPP32 Phosphorylation in Human Medium Spiny Neurons: Implications for Huntington Disease

Stem cell reports, 2019-09, Vol.13 (3), p.448-457

2019

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Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells

PloS one, 2016-02, Vol.11 (2), p.e0148680-e0148680

2016

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Human embryonic stem cells reveal recurrent genomic instability at 20q11.21

Nature biotechnology, 2008-12, Vol.26 (12), p.1364-1366

2008

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Emerging Opportunities in Human Pluripotent Stem-Cells Based Assays to Explore the Diversity of Botulinum Neurotoxins as Future Therapeutics

International journal of molecular sciences, 2021-07, Vol.22 (14), p.7524

2021

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The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

Brain (London, England : 1878), 2018-05, Vol.141 (5), p.1434-1454

2018

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The Postischemic Environment Differentially Impacts Teratoma or Tumor Formation After Transplantation of Human Embryonic Stem Cell-Derived Neural Progenitors

Stroke (1970), 2010, Vol.41 (1), p.153-159

2010

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Early transcriptional changes linked to naturally occurring Huntington's disease mutations in neural derivatives of human embryonic stem cells

Human molecular genetics, 2012-09, Vol.21 (17), p.3883-3895

2012

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Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice

Nature biotechnology, 2003-10, Vol.21 (10), p.1200-1207

2003

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Mono- and Biallelic Inactivation of Huntingtin Gene in Patient-Specific Induced Pluripotent Stem Cells Reveal HTT Roles in Striatal Development and Neuronal Functions

Journal of Huntington's disease, 2024-01, Vol.13 (1), p.41

2024

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PRiMA: The Membrane Anchor of Acetylcholinesterase in the Brain

Neuron (Cambridge, Mass.), 2002-01, Vol.33 (2), p.275-285

2002

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High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes

Stem cells (Dayton, Ohio), 2013-09, Vol.31 (9), p.1816-1828

2013

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Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease

MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates

Propagation of α-Synuclein Strains within Human Reconstructed Neuronal Network

Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines

Modeling and Targeting Neuroglial Interactions with Human Pluripotent Stem Cell Models

Allele-specific silencing of mutant huntingtin in rodent brain and human stem cells

Huntingtin lowering impairs the maturation and synchronized synaptic activity of human cortical neuronal networks derived from induced pluripotent stem cells

The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes

Translating cell therapies for neurodegenerative diseases: Huntington's disease as a model disorder

Longitudinal characterization of cognitive and motor deficits in an excitotoxic lesion model of striatal dysfunction in non-human primates

Derivation of Midbrain Dopamine Neurons from Human Embryonic Stem Cells

Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice

Embryonic stem cells neural differentiation qualifies the role of Wnt/β‐Catenin signals in human telencephalic specification and regionalization

Cell Therapy for Huntington's Disease: Learning from Failure

CTIP2-Regulated Reduction in PKA-Dependent DARPP32 Phosphorylation in Human Medium Spiny Neurons: Implications for Huntington Disease

Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells

Human embryonic stem cells reveal recurrent genomic instability at 20q11.21

Emerging Opportunities in Human Pluripotent Stem-Cells Based Assays to Explore the Diversity of Botulinum Neurotoxins as Future Therapeutics

The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

The Postischemic Environment Differentially Impacts Teratoma or Tumor Formation After Transplantation of Human Embryonic Stem Cell-Derived Neural Progenitors

Early transcriptional changes linked to naturally occurring Huntington's disease mutations in neural derivatives of human embryonic stem cells

Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice

Mono- and Biallelic Inactivation of Huntingtin Gene in Patient-Specific Induced Pluripotent Stem Cells Reveal HTT Roles in Striatal Development and Neuronal Functions

PRiMA: The Membrane Anchor of Acetylcholinesterase in the Brain

High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes

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