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Towards the sustainable discovery and development of new antibiotics

Nature reviews. Chemistry, 2021-10, Vol.5 (10), p.726-749

2021

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Dynamics of the compartmentalized Streptomyces chromosome during metabolic differentiation

Nature communications, 2021-09, Vol.12 (1), p.5221-5221, Article 5221

2021

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The nonribosomal synthesis of diketopiperazines in tRNA-dependent cyclodipeptide synthase pathways

Natural product reports, 2012-01, Vol.29 (9), p.961-979

2012

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A Comprehensive Overview of the Cyclodipeptide Synthase Family Enriched with the Characterization of 32 New Enzymes

Frontiers in microbiology, 2018-02, Vol.9, p.46-46

2018

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Design of a generic CRISPR-Cas9 approach using the same sgRNA to perform gene editing at distinct loci

BMC biotechnology, 2019-03, Vol.19 (1), p.18-8, Article 18

2019

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Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis

Proceedings of the National Academy of Sciences - PNAS, 2009-05, Vol.106 (18), p.7426-7431

2009

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Marker-Free Genome Engineering in Amycolatopsis Using the pSAM2 Site-Specific Recombination System

Microorganisms (Basel), 2022-04, Vol.10 (4), p.828

2022

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Regulation of the Biosynthesis of the Macrolide Antibiotic Spiramycin in Streptomyces ambofaciens

Journal of Bacteriology, 2010-11, Vol.192 (21), p.5813-5821

2010

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A Sweet Origin for the Key Congocidine Precursor 4-Acetamidopyrrole-2-carboxylate

Angewandte Chemie (International ed.), 2012-07, Vol.51 (30), p.7454-7458

International ed. in English, 2012

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Recombinant Environmental Libraries Provide Access to Microbial Diversity for Drug Discovery from Natural Products

Applied and Environmental Microbiology, 2003-01, Vol.69 (1), p.49-55

2003

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Post-PKS Tailoring Steps of the Spiramycin Macrolactone Ring in Streptomyces ambofaciens

Antimicrobial Agents and Chemotherapy, 2013-08, Vol.57 (8), p.3836-3842

2013

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Modular and Integrative Vectors for Synthetic Biology Applications in Streptomyces spp

Applied and environmental microbiology, 2019-08, Vol.85 (16)

2019

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Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens

Microbiology (Society for General Microbiology), 2007-12, Vol.153 (Pt 12), p.4111-4122

2007

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Glycosylation Steps during Spiramycin Biosynthesis in Streptomyces ambofaciens: Involvement of Three Glycosyltransferases and Their Interplay with Two Auxiliary Proteins

Antimicrobial Agents and Chemotherapy, 2010-07, Vol.54 (7), p.2830-2839

2010

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Molecular Basis of Intrinsic Macrolide Resistance in the Mycobacterium tuberculosis Complex

Antimicrobial Agents and Chemotherapy, 2004-01, Vol.48 (1), p.143-150

2004

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Ribosomal RNA operons define a central functional compartment in the Streptomyces chromosome

Nucleic acids research, 2022-11, Vol.50 (20), p.11654-11669

2022

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Evolution of the terminal regions of the Streptomyces linear chromosome

Molecular biology and evolution, 2006-12, Vol.23 (12), p.2361-2369

2006

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Draft Genome Sequence of Streptomyces sp. M1013, a Close Relative of Streptomyces ambofaciens and Streptomyces coelicolor

Genome announcements (Washington, DC), 2017-07, Vol.5 (29)

2017

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Genome mining of Streptomyces ambofaciens

Journal of industrial microbiology & biotechnology, 2014-02, Vol.41 (2), p.251-263

2014

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Revised Structure of Anthelvencin A and Characterization of the Anthelvencin Biosynthetic Gene Cluster

ACS chemical biology, 2020-04, Vol.15 (4), p.945-951

2020

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The Absence of Pupylation (Prokaryotic Ubiquitin-Like Protein Modification) Affects Morphological and Physiological Differentiation in Streptomyces coelicolor

Journal of bacteriology, 2015-11, Vol.197 (21), p.3388-3399

2015

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Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the spiramycin producer

Journal of biotechnology, 2015-11, Vol.214, p.117-118

2015

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Analysis of 51 cyclodipeptide synthases reveals the basis for substrate specificity

Nature chemical biology, 2015-09, Vol.11 (9), p.721-727

2015

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Complete Genome Sequence of Streptomyces sp. TN58, a Producer of Acyl Alpha- l -Rhamnopyranosides

Genome announcements (Washington, DC), 2017-08, Vol.5 (34)

2017

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Characterization of Sviceucin from Streptomyces Provides Insight into Enzyme Exchangeability and Disulfide Bond Formation in Lasso Peptides

ACS chemical biology, 2015-11, Vol.10 (11), p.2641-2649

2015

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Towards the sustainable discovery and development of new antibiotics

Dynamics of the compartmentalized Streptomyces chromosome during metabolic differentiation

The nonribosomal synthesis of diketopiperazines in tRNA-dependent cyclodipeptide synthase pathways

A Comprehensive Overview of the Cyclodipeptide Synthase Family Enriched with the Characterization of 32 New Enzymes

Design of a generic CRISPR-Cas9 approach using the same sgRNA to perform gene editing at distinct loci

Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis

Marker-Free Genome Engineering in Amycolatopsis Using the pSAM2 Site-Specific Recombination System

Regulation of the Biosynthesis of the Macrolide Antibiotic Spiramycin in Streptomyces ambofaciens

A Sweet Origin for the Key Congocidine Precursor 4-Acetamidopyrrole-2-carboxylate

Recombinant Environmental Libraries Provide Access to Microbial Diversity for Drug Discovery from Natural Products

Post-PKS Tailoring Steps of the Spiramycin Macrolactone Ring in Streptomyces ambofaciens

Modular and Integrative Vectors for Synthetic Biology Applications in Streptomyces spp

Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens

Glycosylation Steps during Spiramycin Biosynthesis in Streptomyces ambofaciens: Involvement of Three Glycosyltransferases and Their Interplay with Two Auxiliary Proteins

Molecular Basis of Intrinsic Macrolide Resistance in the Mycobacterium tuberculosis Complex

Ribosomal RNA operons define a central functional compartment in the Streptomyces chromosome

Evolution of the terminal regions of the Streptomyces linear chromosome

Draft Genome Sequence of Streptomyces sp. M1013, a Close Relative of Streptomyces ambofaciens and Streptomyces coelicolor

Genome mining of Streptomyces ambofaciens

Revised Structure of Anthelvencin A and Characterization of the Anthelvencin Biosynthetic Gene Cluster

The Absence of Pupylation (Prokaryotic Ubiquitin-Like Protein Modification) Affects Morphological and Physiological Differentiation in Streptomyces coelicolor

Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the spiramycin producer

Analysis of 51 cyclodipeptide synthases reveals the basis for substrate specificity

Complete Genome Sequence of Streptomyces sp. TN58, a Producer of Acyl Alpha- l -Rhamnopyranosides

Characterization of Sviceucin from Streptomyces Provides Insight into Enzyme Exchangeability and Disulfide Bond Formation in Lasso Peptides

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