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Pyrrolo[2,3‐d]pyrimidine (7‐deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides

Medicinal research reviews, 2017-11, Vol.37 (6), p.1429-1460

2017

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Correction to “Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7‑Deazapurine Ribonucleosides”

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1698-1698

2019

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2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove

Angewandte Chemie (International ed.), 2016-12, Vol.55 (51), p.15856-15859

International ed. in English, 2016

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Synthesis, Cytostatic, Antimicrobial, and Anti-HCV Activity of 6‑Substituted 7‑(Het)aryl-7-deazapurine Ribonucleosides

Journal of medicinal chemistry, 2014-02, Vol.57 (3), p.1097-1110

2014

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Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7‑Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists

Journal of medicinal chemistry, 2022-10, Vol.65 (20), p.14082-14103

2022

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Synthesis of cytochalasan analogues with aryl substituents at position 10

Organic & biomolecular chemistry, 2024-06, Vol.22 (22), p.4536-4549

2024

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Enzymatic synthesis of base-modified RNA by T7 RNA polymerase. A systematic study and comparison of 5-substituted pyrimidine and 7-substituted 7-deazapurine nucleoside triphosphates as substrates

Organic & biomolecular chemistry, 2018, Vol.16 (32), p.5800-5807

2018

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Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7‑Deazapurine Ribonucleosides

Journal of medicinal chemistry, 2018-10, Vol.61 (20), p.9347-9359

2018

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Synthesis and Significant Cytostatic Activity of 7-Hetaryl-7-deazaadenosines

Journal of medicinal chemistry, 2011-08, Vol.54 (15), p.5498-5507

2011

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Inhibition of non-templated nucleotide addition by DNA polymerases in primer extension using twisted intercalating nucleic acid modified templates

Bioorganic & medicinal chemistry letters, 2016-01, Vol.26 (2), p.288-291

2016

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6-Aryl-4-amino-pyrimido[4,5-b]indole 2′-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study

Bioorganic & medicinal chemistry, 2016-10, Vol.24 (19), p.4528-4535

2016

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Polymerase Synthesis and Restriction Enzyme Cleavage of DNA Containing 7-Substituted 7-Deazaguanine Nucleobases

Chembiochem : a European journal of chemical biology, 2015-10, Vol.16 (15), p.2225-2236

2015

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Synthesis and Cytotoxic and Antiviral Activity Profiling of All‐Four Isomeric Series of Pyrido‐Fused 7‐Deazapurine Ribonucleosides

Chemistry : a European journal, 2020-10, Vol.26 (57), p.13002-13015

2020

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Isomeric Naphtho‐Fused 7‐Deazapurine Nucleosides and Nucleotides: Synthesis, Biological Activity, Photophysical Properties and Enzymatic Incorporation to Nucleic Acids

European journal of organic chemistry, 2018-10, Vol.2018 (37), p.5092-5108

2018

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Synthesis and migrastatic activity of cytochalasin analogues lacking a macrocyclic moiety

RSC medicinal chemistry, 2024-01, Vol.15 (1), p.322-343

2024

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Synthesis and Antitrypanosomal Activity of 6‑Substituted 7‑Methyl-7-deazapurine Nucleosides

ACS infectious diseases, 2021-04, Vol.7 (4), p.917-926

2021

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7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action

Molecular cancer therapeutics, 2016-05, Vol.15 (5), p.922-937

2016

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Unlocked Nucleic Acids with a Pyrene-Modified Uracil: Synthesis, Hybridization Studies, Fluorescent Properties and i-Motif Stability

Chembiochem : a European journal of chemical biology, 2014-01, Vol.15 (1), p.146-156

2014

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Enzymatic synthesis of base-modified RNA by T7 RNA polymerase. A systematic study and comparison of 5-substituted pyrimidine and 7-substituted 7-deazapurine nucleoside triphosphates as substratesElectronic supplementary information (ESI) available: Full experimental part, characterization of all compounds, additional gels and copies of spectra. See DOI: 10.1039/c8ob01498a

2018-08

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Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases

Nucleic acids research, 2016-04, Vol.44 (7), p.3000

2016

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Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides

Bioorganic & medicinal chemistry, 2015-12, Vol.23 (23), p.7422-7438

2015

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Synthesis of 2′-deoxy-2′-fluororibo- and 2′-deoxy-2′,2′-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines

Tetrahedron, 2012-09, Vol.68 (39), p.8300-8310

2012

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Bis-Pyrene-Modified Unlocked Nucleic Acids: Synthesis, Hybridization Studies, and Fluorescent Properties

ChemMedChem, 2014-09, Vol.9 (9), p.2120-2127

2014

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Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′-fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides

Bioorganic & medicinal chemistry, 2012-09, Vol.20 (17), p.5202-5214

2012

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Synthesis and Cytostatic and Antiviral Activities of 2′-Deoxy-2′,2′-difluororibo- and 2′-Deoxy-2′-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines

ChemMedChem, 2013-05, Vol.8 (5), p.832-846

2013

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Pyrrolo[2,3‐d]pyrimidine (7‐deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides

Correction to “Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7‑Deazapurine Ribonucleosides”

2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove

Synthesis, Cytostatic, Antimicrobial, and Anti-HCV Activity of 6‑Substituted 7‑(Het)aryl-7-deazapurine Ribonucleosides

Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7‑Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists

Synthesis of cytochalasan analogues with aryl substituents at position 10

Enzymatic synthesis of base-modified RNA by T7 RNA polymerase. A systematic study and comparison of 5-substituted pyrimidine and 7-substituted 7-deazapurine nucleoside triphosphates as substrates

Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7‑Deazapurine Ribonucleosides

Synthesis and Significant Cytostatic Activity of 7-Hetaryl-7-deazaadenosines

Inhibition of non-templated nucleotide addition by DNA polymerases in primer extension using twisted intercalating nucleic acid modified templates

6-Aryl-4-amino-pyrimido[4,5-b]indole 2′-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study

Polymerase Synthesis and Restriction Enzyme Cleavage of DNA Containing 7-Substituted 7-Deazaguanine Nucleobases

Synthesis and Cytotoxic and Antiviral Activity Profiling of All‐Four Isomeric Series of Pyrido‐Fused 7‐Deazapurine Ribonucleosides

Isomeric Naphtho‐Fused 7‐Deazapurine Nucleosides and Nucleotides: Synthesis, Biological Activity, Photophysical Properties and Enzymatic Incorporation to Nucleic Acids

Synthesis and migrastatic activity of cytochalasin analogues lacking a macrocyclic moiety

Synthesis and Antitrypanosomal Activity of 6‑Substituted 7‑Methyl-7-deazapurine Nucleosides

7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action

Unlocked Nucleic Acids with a Pyrene-Modified Uracil: Synthesis, Hybridization Studies, Fluorescent Properties and i-Motif Stability

Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases

Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides

Synthesis of 2′-deoxy-2′-fluororibo- and 2′-deoxy-2′,2′-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines

Bis-Pyrene-Modified Unlocked Nucleic Acids: Synthesis, Hybridization Studies, and Fluorescent Properties

Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′-fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides

Synthesis and Cytostatic and Antiviral Activities of 2′-Deoxy-2′,2′-difluororibo- and 2′-Deoxy-2′-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines

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