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mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and aging

Annals of the New York Academy of Sciences, 2015-06, Vol.1346 (1), p.33-44

Perl, Andras

2015

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Oxidative stress in the pathology and treatment of systemic lupus erythematosus

Nature reviews. Rheumatology, 2013-11, Vol.9 (11), p.674

Perl, Andras

2013

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Review: Metabolic Control of Immune System Activation in Rheumatic Diseases

Arthritis & rheumatology (Hoboken, N.J.), 2017-12, Vol.69 (12), p.2259-2270

Perl, Andras

2017

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The Influence of Reactive Oxygen Species in the Immune System and Pathogenesis of Multiple Sclerosis

Autoimmune diseases, 2020, Vol.2020, p.1-14

2020

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Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases

Nature reviews. Rheumatology, 2016-03, Vol.12 (3), p.169

Perl, Andras

2016

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Metabolism as a Target for Modulation in Autoimmune Diseases

Trends in immunology, 2018-07, Vol.39 (7), p.562-576

2018

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Increased Circulating Th17 Cells, Serum IL-17A, and IL-23 in Takayasu Arteritis

Autoimmune Diseases, 2016-01, Vol.2016, p.7841718-8

2016

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Pathogenesis and treatment of autoimmune rheumatic diseases

Current opinion in rheumatology, 2019-05, Vol.31 (3), p.307

2019

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Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogrenʼs syndrome

Current opinion in rheumatology, 2009-09, Vol.21 (5), p.443-447

Perl, Andras

2009

Volltextzugriff (PDF)

Double-Edged Sword: Interleukin-2 Promotes T Regulatory Cell Differentiation but Also Expands Interleukin-13- and Interferon-γ-Producing CD8 + T Cells via STAT6-GATA-3 Axis in Systemic Lupus Erythematosus

Frontiers in immunology, 2021-03, Vol.12, p.635531

2021

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Adenosine receptor 2a agonists target mouse CD11c + T-bet + B cells in infection and autoimmunity

Nature communications, 2022-01, Vol.13 (1), p.452-452, Article 452

2022

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Endosome Traffic Modulates Pro-Inflammatory Signal Transduction in CD4 + T Cells-Implications for the Pathogenesis of Systemic Lupus Erythematosus

International journal of molecular sciences, 2023-06, Vol.24 (13), p.10749

2023

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Expanding scope of TEMRA in autoimmunity

EBioMedicine, 2023-04, Vol.90, p.104520-104520, Article 104520

2023

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Mitochondrial Dysfunction in the Liver and Antiphospholipid Antibody Production Precede Disease Onset and Respond to Rapamycin in Lupus‐Prone Mice

Arthritis & rheumatology (Hoboken, N.J.), 2016-11, Vol.68 (11), p.2728-2739

2016

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Editorial: Mitochondrial dysfunction in inflammation and autoimmunity

Frontiers in immunology, 2023-10, Vol.14, p.1304315-1304315

2023

Volltextzugriff (PDF)

Recurrent brachial plexopathy as initial presentation of systemic lupus erythematosus: A case report and review of the literature

Lupus, 2022-04, Vol.31 (4), p.500-504

2022

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Rodent models of experimental autoimmune uveitis

Methods in molecular biology (Clifton, N.J.), 2012, Vol.900, p.443

2012

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Blockade of Treg Cell Differentiation and Function by the Interleukin‐21–Mechanistic Target of Rapamycin Axis Via Suppression of Autophagy in Patients With Systemic Lupus Erythematosus

Arthritis & rheumatology (Hoboken, N.J.), 2018-03, Vol.70 (3), p.427-438

2018

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Mouse models of multiple sclerosis: experimental autoimmune encephalomyelitis and Theiler's virus-induced demyelinating disease

Methods in molecular biology (Clifton, N.J.), 2012, Vol.900, p.381

2012

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Cell type-specific mechanistic target of rapamycin-dependent distortion of autophagy pathways in lupus nephritis

Translational research : the journal of laboratory and clinical medicine, 2022-07, Vol.245, p.55-81

2022

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Activation of the Mechanistic Target of Rapamycin in SLE: Explosion of Evidence in the Last Five Years

Current rheumatology reports, 2016-12, Vol.18 (12), p.73-73, Article 73

2016

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Interplay of infections, autoimmunity, and immunosuppression in systemic lupus erythematosus

International reviews of immunology, 2014-07, Vol.33 (4), p.330

2014

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CD8+DR+ T-Cells and C3 Complement Serum Concentration as Potential Biomarkers in Thrombotic Antiphospholipid Syndrome

Autoimmune Diseases, 2014-01, Vol.2014 (2014), p.868652-8

2014

Volltextzugriff (PDF)

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE

Annals of the rheumatic diseases, 2014-10, Vol.73 (10), p.1888-1897

2014

Volltextzugriff (PDF)

The mTOR pathway in the antiphospholipid syndrome

Medical Review, 2023-12, Vol.3 (6), p.511-513

2023

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mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and aging

Oxidative stress in the pathology and treatment of systemic lupus erythematosus

Review: Metabolic Control of Immune System Activation in Rheumatic Diseases

The Influence of Reactive Oxygen Species in the Immune System and Pathogenesis of Multiple Sclerosis

Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases

Metabolism as a Target for Modulation in Autoimmune Diseases

Increased Circulating Th17 Cells, Serum IL-17A, and IL-23 in Takayasu Arteritis

Pathogenesis and treatment of autoimmune rheumatic diseases

Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogrenʼs syndrome

Double-Edged Sword: Interleukin-2 Promotes T Regulatory Cell Differentiation but Also Expands Interleukin-13- and Interferon-γ-Producing CD8 + T Cells via STAT6-GATA-3 Axis in Systemic Lupus Erythematosus

Adenosine receptor 2a agonists target mouse CD11c + T-bet + B cells in infection and autoimmunity

Endosome Traffic Modulates Pro-Inflammatory Signal Transduction in CD4 + T Cells-Implications for the Pathogenesis of Systemic Lupus Erythematosus

Expanding scope of TEMRA in autoimmunity

Mitochondrial Dysfunction in the Liver and Antiphospholipid Antibody Production Precede Disease Onset and Respond to Rapamycin in Lupus‐Prone Mice

Editorial: Mitochondrial dysfunction in inflammation and autoimmunity

Recurrent brachial plexopathy as initial presentation of systemic lupus erythematosus: A case report and review of the literature

Rodent models of experimental autoimmune uveitis

Blockade of Treg Cell Differentiation and Function by the Interleukin‐21–Mechanistic Target of Rapamycin Axis Via Suppression of Autophagy in Patients With Systemic Lupus Erythematosus

Mouse models of multiple sclerosis: experimental autoimmune encephalomyelitis and Theiler's virus-induced demyelinating disease

Cell type-specific mechanistic target of rapamycin-dependent distortion of autophagy pathways in lupus nephritis

Activation of the Mechanistic Target of Rapamycin in SLE: Explosion of Evidence in the Last Five Years

Interplay of infections, autoimmunity, and immunosuppression in systemic lupus erythematosus

CD8+DR+ T-Cells and C3 Complement Serum Concentration as Potential Biomarkers in Thrombotic Antiphospholipid Syndrome

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE

The mTOR pathway in the antiphospholipid syndrome

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