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Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes

eLife, 2020-12, Vol.9

2020

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Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD

Nature communications, 2021-08, Vol.12 (1), p.5004-5004, Article 5004

2021

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Infancy‐onset diabetes caused by de‐regulated AMPylation of the human endoplasmic reticulum chaperone BiP

EMBO molecular medicine, 2023-03, Vol.15 (3), p.e16491-n/a

2023

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FICD acts bifunctionally to AMPylate and de-AMPylate the endoplasmic reticulum chaperone BiP

Nature structural & molecular biology, 2017-01, Vol.24 (1), p.23

2017

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ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B

Molecular cell, 2021-01, Vol.81 (1), p.88-103.e6

2021

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An oligomeric state‐dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP

The EMBO journal, 2019-10, Vol.38 (21), p.e102177-n/a

2019

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An oligomeric state‐dependent switch in the ER enzyme FICD regulates AMP ylation and de AMP ylation of BiP

The EMBO journal, 2019-11, Vol.38 (21)

2019

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A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA

Nature communications, 2018-12, Vol.9 (1), p.5447-14, Article 5447

2018

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A droplet digital PCR (ddPCR) assay to detect Helicoverpa armigera (Lepidoptera: Noctuidae) in bulk trap samples

PloS one, 2017-05, Vol.12 (5), p.e0178704-e0178704

2017

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Does Bevacizumab Improve Outcomes After Ahmed Glaucoma Valve Implantation for Refractory Glaucoma?: A Meta-Analysis

Journal of glaucoma, 2024-06, Vol.33 (6), p.444

2024

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Cardiac Complications of Common Drugs of Abuse: Pharmacology, Toxicology, and Management

Canadian journal of cardiology, 2022-09, Vol.38 (9), p.1331-1341

2022

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Evaluating the role of salt intake in achieving WHO NCD targets in the Eurasian Economic Union: A PRIME modeling study

PloS one, 2023-07, Vol.18 (7), p.e0289112-e0289112

2023

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Perceptions of Facilitators and Barriers to Smoking Cessation Among Patients and Providers in a Cancer Center: A Single Institution Qualitative Exploratory Study

Integrative cancer therapies, 2023-01, Vol.22, p.15347354231198072-15347354231198072

2023

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642P Frequency and impact of retreatment in relapsed refractory multiple myeloma (RRMM): Real-world survey conducted in 5 European countries (United Kingdom, France, Germany, Italy, Spain)

Annals of oncology, 2022-09, Vol.33, p.S835-S836

2022

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644P Treatment patterns, outcomes, and physician decision-making in multiple myeloma: A real-world European study

Annals of oncology, 2022-09, Vol.33, p.S836

2022

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Combined Approach to Phacoemulsification and Trabeculectomy Results in Less Ideal Refractive Outcomes Compared With the Sequential Approach

Journal of glaucoma, 2016-10, Vol.25 (10), p.e873-e878

2016

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A Chromosome-Scale Genome Assembly of a Helicoverpa zea Strain Resistant to Bacillus thuringiensis Cry1Ac Insecticidal Protein

Genome biology and evolution, 2023-03, Vol.15 (3)

2023

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A Thematic Analysis of Career Adaptability in Retirees Who Return to Work

Frontiers in psychology, 2016-02, Vol.7, p.193-193

2016

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A case study using spectroscopy and computational modelling for Co speciation in a deep eutectic solvent

Physical chemistry chemical physics : PCCP, 2024-07

2024

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Syntaxin 6 regulates Glut4 trafficking in 3T3-L1 adipocytes

Molecular biology of the cell, 2003-07, Vol.14 (7), p.2946-2958

2003

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"Bodhicitta" and Charity: A Comparison

Buddhist-Christian studies, 2015-01, Vol.35 (1), p.121-146

Perera, Luke

2015

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A Community-Based Intervention for Managing Hypertension in Rural South Asia

The New England journal of medicine, 2020-02, Vol.382 (8), p.717-726

2020

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Uptake of SGLT2i and Outcomes in Patients with Diabetes and Heart Failure: A Population-Based Cohort and a Specialized Clinic Cohort

The American heart journal, 2024-08, Vol.274, p.11-22

2024

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Invasive coronary physiology in patients with angina and non-obstructive coronary artery disease: a consensus document from the coronary microvascular dysfunction workstream of the British Heart Foundation/National Institute for Health Research Partnership

Heart (British Cardiac Society), 2023-01, Vol.109 (2), p.88

2023

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1029P Dazostinag (TAK-676) alone and in combination with pembrolizumab (pembro) in patients (pts) with advanced or metastatic solid tumors: Preliminary safety, PK/PD, and anti-tumor activity in a phase I dose escalation study supporting a recommended dose for expansion (RDE)

Annals of oncology, 2023-10, Vol.34, p.S625-S626

2023

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Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes

Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD

Infancy‐onset diabetes caused by de‐regulated AMPylation of the human endoplasmic reticulum chaperone BiP

FICD acts bifunctionally to AMPylate and de-AMPylate the endoplasmic reticulum chaperone BiP

ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B

An oligomeric state‐dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP

An oligomeric state‐dependent switch in the ER enzyme FICD regulates AMP ylation and de AMP ylation of BiP

A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA

A droplet digital PCR (ddPCR) assay to detect Helicoverpa armigera (Lepidoptera: Noctuidae) in bulk trap samples

Does Bevacizumab Improve Outcomes After Ahmed Glaucoma Valve Implantation for Refractory Glaucoma?: A Meta-Analysis

Cardiac Complications of Common Drugs of Abuse: Pharmacology, Toxicology, and Management

Evaluating the role of salt intake in achieving WHO NCD targets in the Eurasian Economic Union: A PRIME modeling study

Perceptions of Facilitators and Barriers to Smoking Cessation Among Patients and Providers in a Cancer Center: A Single Institution Qualitative Exploratory Study

642P Frequency and impact of retreatment in relapsed refractory multiple myeloma (RRMM): Real-world survey conducted in 5 European countries (United Kingdom, France, Germany, Italy, Spain)

644P Treatment patterns, outcomes, and physician decision-making in multiple myeloma: A real-world European study

Combined Approach to Phacoemulsification and Trabeculectomy Results in Less Ideal Refractive Outcomes Compared With the Sequential Approach

A Chromosome-Scale Genome Assembly of a Helicoverpa zea Strain Resistant to Bacillus thuringiensis Cry1Ac Insecticidal Protein

A Thematic Analysis of Career Adaptability in Retirees Who Return to Work

A case study using spectroscopy and computational modelling for Co speciation in a deep eutectic solvent

Syntaxin 6 regulates Glut4 trafficking in 3T3-L1 adipocytes

"Bodhicitta" and Charity: A Comparison

A Community-Based Intervention for Managing Hypertension in Rural South Asia

Uptake of SGLT2i and Outcomes in Patients with Diabetes and Heart Failure: A Population-Based Cohort and a Specialized Clinic Cohort

Invasive coronary physiology in patients with angina and non-obstructive coronary artery disease: a consensus document from the coronary microvascular dysfunction workstream of the British Heart Foundation/National Institute for Health Research Partnership

1029P Dazostinag (TAK-676) alone and in combination with pembrolizumab (pembro) in patients (pts) with advanced or metastatic solid tumors: Preliminary safety, PK/PD, and anti-tumor activity in a phase I dose escalation study supporting a recommended dose for expansion (RDE)

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