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Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?

Cell death & disease, 2021-06, Vol.12 (6), p.592-592, Article 592

2021

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Role of hypothalamic neurogenesis in feeding regulation

Trends in endocrinology and metabolism, 2014-02, Vol.25 (2), p.80-88

2014

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miR‐155 modulates microglia‐mediated immune response by down‐regulating SOCS‐1 and promoting cytokine and nitric oxide production

Immunology, 2012-01, Vol.135 (1), p.73-88

2012

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Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway

Nature communications, 2016-05, Vol.7 (1), p.11445-11445, Article 11445

2016

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Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice

Brain (London, England : 1878), 2015-02, Vol.138 (Pt 2), p.320-335

2015

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Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype

Biomaterials, 2016-03, Vol.82, p.124-137

2016

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SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway

International journal of molecular sciences, 2022-06, Vol.23 (12), p.6790

2022

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Polyglutamine Disorders

1st ed. 2018 edition., 2018

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Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice

PloS one, 2013-01, Vol.8 (1), p.e52396

2013

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Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado―Joseph disease

Brain (London, England : 1878), 2013-07, Vol.136 (Pt 7), p.2173-2188

2013

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Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells

The journals of gerontology. Series A, Biological sciences and medical sciences, 2020-05, Vol.75 (6), p.1073-1078

2020

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Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease

Brain (London, England : 1878), 2011-05, Vol.134 (Pt 5), p.1400-1415

2011

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Living Proof of Activity of Extracellular Vesicles in the Central Nervous System

International journal of molecular sciences, 2021-07, Vol.22 (14), p.7294

2021

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RNA interference mitigates motor and neuropathological deficits in a cerebellar mouse model of Machado-Joseph disease

PloS one, 2014-08, Vol.9 (8), p.e100086-e100086

2014

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Phosphoproteome Microarray Analysis of Extracellular Particles as a Tool to Explore Novel Biomarker Candidates for Alzheimer's Disease

International journal of molecular sciences, 2024-02, Vol.25 (3), p.1584

2024

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Neuropeptide Y stimulates autophagy in hypothalamic neurons

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (13), p.E1642-E1651

2015

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Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease

PloS one, 2008-10, Vol.3 (10), p.e3341-e3341

2008

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Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease

Brain (London, England : 1878), 2015-12, Vol.138 (Pt 12), p.3537-3554

2015

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Caffeine alleviates progressive motor deficits in a transgenic mouse model of spinocerebellar ataxia

Annals of neurology, 2017-03, Vol.81 (3), p.407-418

2017

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A Novel Genetic Variant in MBD5 Associated with Severe Epilepsy and Intellectual Disability: Potential Implications on Neural Primary Cilia

International journal of molecular sciences, 2023-08, Vol.24 (16), p.12603

2023

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Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation

Aging (Albany, NY.), 2016-07, Vol.8 (7), p.1470-1484

2016

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Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy

Cell death & disease, 2021-11, Vol.12 (12), p.1117-13, Article 1117

2021

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Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado―Joseph disease

Brain (London, England : 1878), 2012-08, Vol.135 (Pt 8), p.2428-2439

2012

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Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult rats

PloS one, 2011-07, Vol.6 (7), p.e22333-e22333

2011

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Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive Review

Frontiers in neuroscience, 2016-12, Vol.10, p.572-572

2016

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Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?

Role of hypothalamic neurogenesis in feeding regulation

miR‐155 modulates microglia‐mediated immune response by down‐regulating SOCS‐1 and promoting cytokine and nitric oxide production

Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway

Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice

Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype

SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway

Polyglutamine Disorders

Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice

Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado―Joseph disease

Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells

Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease

Living Proof of Activity of Extracellular Vesicles in the Central Nervous System

RNA interference mitigates motor and neuropathological deficits in a cerebellar mouse model of Machado-Joseph disease

Phosphoproteome Microarray Analysis of Extracellular Particles as a Tool to Explore Novel Biomarker Candidates for Alzheimer's Disease

Neuropeptide Y stimulates autophagy in hypothalamic neurons

Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease

Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease

Caffeine alleviates progressive motor deficits in a transgenic mouse model of spinocerebellar ataxia

A Novel Genetic Variant in MBD5 Associated with Severe Epilepsy and Intellectual Disability: Potential Implications on Neural Primary Cilia

Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation

Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado―Joseph disease

Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult rats

Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive Review

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