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Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicities

Toxicological sciences, 2011-03, Vol.120 Suppl 1 (Supplement 1), p.S49-S75

2011

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Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study

Critical reviews in toxicology, 2014-01, Vol.44 (1), p.83-119

2014

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Association of the Ah receptor with the 90-kDa heat shock protein

The Journal of biological chemistry, 1988-09, Vol.263 (27), p.13802-13805

Perdew, G H

1988

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Characterization of the AhR−hsp90−XAP2 Core Complex and the Role of the Immunophilin-Related Protein XAP2 in AhR Stabilization

Biochemistry (Easton), 1999-07, Vol.38 (28), p.8907-8917

1999

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Hepatitis B Virus X-Associated Protein 2 Is a Subunit of the Unliganded Aryl Hydrocarbon Receptor Core Complex and Exhibits Transcriptional Enhancer Activity

Molecular and Cellular Biology, 1998-02, Vol.18 (2), p.978-988

1998

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The aryl hydrocarbon receptor complex and the control of gene expression

Critical reviews in eukaryotic gene expression, 2008, Vol.18 (3), p.207-250

2008

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Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system

The Journal of biological chemistry, 1993-10, Vol.268 (29), p.21711-21716

1993

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Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2

The Journal of biological chemistry, 2003-02, Vol.278 (7), p.4467-4473

2003

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Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo

Developmental dynamics, 1995-10, Vol.204 (2), p.133-143

1995

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Characterization of a Subset of the Basic-Helix-Loop-Helix-PAS Superfamily That Interacts with Components of the Dioxin Signaling Pathway

The Journal of biological chemistry, 1997-03, Vol.272 (13), p.8581-8593

1997

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Subcellular Localization of the Aryl Hydrocarbon Receptor Is Modulated by the Immunophilin Homolog Hepatitis B Virus X-associated Protein 2

The Journal of biological chemistry, 2000-12, Vol.275 (48), p.37448-37453

2000

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1075 From old king coal to novel therapeutics for inflammatory skin diseases: The aryl hydrocarbon Receptor as a therapeutic target

Journal of investigative dermatology, 2018-05, Vol.138 (5), p.S182-S182

2018

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Subunit composition of the heteromeric cytosolic aryl hydrocarbon receptor complex

The Journal of biological chemistry, 1994-11, Vol.269 (44), p.27554-27558

1994

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Ah Receptor in Embryonic Mouse Palate and Effects of TCDD on Receptor Expression

Toxicology and applied pharmacology, 1994-05, Vol.126 (1), p.16-25

1994

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Evidence that the 90-kDa heat shock protein (HSP90) exists in cytosol in heteromeric complexes containing HSP70 and three other proteins with Mr of 63,000, 56,000, and 50,000

The Journal of biological chemistry, 1991-04, Vol.266 (11), p.6708-6713

1991

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Protein Kinase C Activity Is Required for Aryl Hydrocarbon Receptor Pathway-Mediated Signal Transduction

Molecular pharmacology, 1998-04, Vol.53 (4), p.691-700

1998

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Quantitative expression patterns of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) protein in mice

Biochemical and biophysical research communications, 2008-07, Vol.371 (3), p.456-461

2008

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Divergent Roles of Hepatitis B Virus X-Associated Protein 2 (XAP2) in Human versus Mouse Ah Receptor Complexes

Biochemistry (Easton), 2004-01, Vol.43 (3), p.700-709

2004

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Mapping the 90 kDa heat shock protein binding region of the Ah receptor

Biochemistry and molecular biology international, 1996-06, Vol.39 (3), p.589-593

1996

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The Q-rich subdomain of the human Ah receptor transactivation domain is required for dioxin-mediated transcriptional activity

The Journal of biological chemistry, 2001-11, Vol.276 (45), p.42302-42310

2001

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Interactive Regulation of Ah and Glucocorticoid Receptors in the Synergistic Induction of Cleft Palate by 2,3,7,8-Tetrachlorodibenzo- p-dioxin and Hydrocortisone

Toxicology and applied pharmacology, 1994-09, Vol.128 (1), p.138-150

1994

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Chemical cross-linking of the cytosolic and nuclear forms of the Ah receptor in hepatoma cell line 1c1c7

Biochemical and biophysical research communications, 1992-01, Vol.182 (1), p.55-62

Perdew, Gary H.

1992

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A Model of Protein Targeting Mediated by Immunophilins and Other Proteins That Bind to hsp90 via Tetratricopeptide Repeat Domains

The Journal of biological chemistry, 1996-06, Vol.271 (23), p.13468-13475

1996

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Aryl hydrocarbon (Ah) receptor levels are selectively modulated by hsp90-associated immunophilin homolog XAP2

Cell stress & chaperones, 2000-07, Vol.5 (3), p.243-254

2000

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Nuclear Receptor Coactivator SRC-1 Interacts With the Q-Rich Subdomain of the AhR and Modulates its Transactivation Potential

Gene expression, 1999-01, Vol.8 (5-6), p.273-286

1999

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Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicities

Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study

Association of the Ah receptor with the 90-kDa heat shock protein

Characterization of the AhR−hsp90−XAP2 Core Complex and the Role of the Immunophilin-Related Protein XAP2 in AhR Stabilization

Hepatitis B Virus X-Associated Protein 2 Is a Subunit of the Unliganded Aryl Hydrocarbon Receptor Core Complex and Exhibits Transcriptional Enhancer Activity

The aryl hydrocarbon receptor complex and the control of gene expression

Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system

Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2

Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo

Characterization of a Subset of the Basic-Helix-Loop-Helix-PAS Superfamily That Interacts with Components of the Dioxin Signaling Pathway

Subcellular Localization of the Aryl Hydrocarbon Receptor Is Modulated by the Immunophilin Homolog Hepatitis B Virus X-associated Protein 2

1075 From old king coal to novel therapeutics for inflammatory skin diseases: The aryl hydrocarbon Receptor as a therapeutic target

Subunit composition of the heteromeric cytosolic aryl hydrocarbon receptor complex

Ah Receptor in Embryonic Mouse Palate and Effects of TCDD on Receptor Expression

Evidence that the 90-kDa heat shock protein (HSP90) exists in cytosol in heteromeric complexes containing HSP70 and three other proteins with Mr of 63,000, 56,000, and 50,000

Protein Kinase C Activity Is Required for Aryl Hydrocarbon Receptor Pathway-Mediated Signal Transduction

Quantitative expression patterns of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) protein in mice

Divergent Roles of Hepatitis B Virus X-Associated Protein 2 (XAP2) in Human versus Mouse Ah Receptor Complexes

Mapping the 90 kDa heat shock protein binding region of the Ah receptor

The Q-rich subdomain of the human Ah receptor transactivation domain is required for dioxin-mediated transcriptional activity

Interactive Regulation of Ah and Glucocorticoid Receptors in the Synergistic Induction of Cleft Palate by 2,3,7,8-Tetrachlorodibenzo- p-dioxin and Hydrocortisone

Chemical cross-linking of the cytosolic and nuclear forms of the Ah receptor in hepatoma cell line 1c1c7

A Model of Protein Targeting Mediated by Immunophilins and Other Proteins That Bind to hsp90 via Tetratricopeptide Repeat Domains

Aryl hydrocarbon (Ah) receptor levels are selectively modulated by hsp90-associated immunophilin homolog XAP2

Nuclear Receptor Coactivator SRC-1 Interacts With the Q-Rich Subdomain of the AhR and Modulates its Transactivation Potential

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