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From MGUS to Multiple Myeloma, a Paradigm for Clonal Evolution of Premalignant Cells

Cancer research (Chicago, Ill.), 2018-05, Vol.78 (10), p.2449-2456

2018

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Role and Regulation of Pro-survival BCL-2 Proteins in Multiple Myeloma

Frontiers in oncology, 2018-11, Vol.8, p.533-533

2018

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Phosphatase PP2A enhances MCL-1 protein half-life in multiple myeloma cells

Cell death & disease, 2021-03, Vol.12 (3), p.229-229, Article 229

2021

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Advances and Perspectives in the Treatment of B-Cell Malignancies

Cancers, 2021-05, Vol.13 (9), p.2266

2021

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Wnt signaling in multiple myeloma: a central player in disease with therapeutic potential

Journal of hematology and oncology, 2018-05, Vol.11 (1), p.67-67, Article 67

2018

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Mcl-1 is essential for the survival of plasma cells

Nature immunology, 2013-03, Vol.14 (3), p.290

2013

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Mcl-1 Is Essential for Germinal Center Formation and B Cell Memory

Science (American Association for the Advancement of Science), 2010-11, Vol.330 (6007), p.1095-1099

2010

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CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production

The Journal of clinical investigation, 2010-01, Vol.120 (1), p.168-178

2010

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Nivolumab plus Brentuximab vedotin +/- bendamustine combination therapy: a safe and effective treatment in pediatric recurrent and refractory classical Hodgkin lymphoma

Frontiers in immunology, 2023, Vol.14, p.1229558-1229558

2023

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Multiple Myeloma Relapse Is Associated with Increased NFκB Pathway Activity and Upregulation of the Pro-Survival BCL-2 Protein BFL-1

Cancers, 2021-09, Vol.13 (18), p.4668

2021

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Dinaciclib synergizes with BH3 mimetics targeting BCL‐2 and BCL‐XL in multiple myeloma cell lines partially dependent on MCL‐1 and in plasma cells from patients

Molecular oncology, 2023-12, Vol.17 (12), p.2507-2525

2023

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c-Myb Regulates the T-Bet-Dependent Differentiation Program in B Cells to Coordinate Antibody Responses

Cell reports (Cambridge), 2017-04, Vol.19 (3), p.461-470

2017

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Identifying clinical response to daratumumab therapy in relapsed/refractory multiple myeloma using a patient‐derived in vitro model

EJHaem, 2024-02, Vol.5 (1), p.141-146

2024

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Serpin B9 controls tumor cell killing by CAR T cells

Journal for immunotherapy of cancer, 2023-03, Vol.11 (3), p.e006364

2023

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DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice

Nature communications, 2017-10, Vol.8 (1), p.1028-12, Article 1028

2017

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Through a glass less darkly: apoptosis and the germinal center response to antigen

Immunological reviews, 2012-05, Vol.247 (1), p.93-106

2012

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Monovalent Ligation of the B Cell Receptor Induces Receptor Activation but Fails to Promote Antigen Presentation

Proceedings of the National Academy of Sciences - PNAS, 2006-02, Vol.103 (9), p.3327-3332

2006

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Endochondral Bone Regeneration by Non-autologous Mesenchymal Stem Cells

Frontiers in bioengineering and biotechnology, 2020-07, Vol.8, p.651-651

2020

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Mice deficient for CD137 ligand are predisposed to develop germinal center–derived B-cell lymphoma

Blood, 2009-09, Vol.114 (11), p.2280-2289

2009

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Bridging the gap between scientific discoveries and clinical application at the Utrecht Science Park

Immunology and cell biology, 2024-04, Vol.102 (4), p.232-234

2024

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Inhibitory pattern recognition receptors

The Journal of experimental medicine, 2022-01, Vol.219 (1)

2022

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Functional disparities among BCL-2 members in tonsillar and leukemic B-cell subsets assessed by BH3-mimetic profiling

Cell death and differentiation, 2017-01, Vol.24 (1), p.111-119

2017

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In Vitro Model to Predict Response to Daratumumab Therapy in Relapsed/Refractory Multiple Myeloma

Blood, 2021-11, Vol.138 (Supplement 1), p.1568-1568

2021

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CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17-producing γδ T cell subsets

Nature immunology, 2009-04, Vol.10 (4), p.427-436

2009

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Targeting B-cell maturation antigen increases sensitivity of multiple myeloma cells to MCL-1 inhibition

Haematologica (Roma), 2022-04, Vol.107 (4), p.980

2022

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From MGUS to Multiple Myeloma, a Paradigm for Clonal Evolution of Premalignant Cells

Role and Regulation of Pro-survival BCL-2 Proteins in Multiple Myeloma

Phosphatase PP2A enhances MCL-1 protein half-life in multiple myeloma cells

Advances and Perspectives in the Treatment of B-Cell Malignancies

Wnt signaling in multiple myeloma: a central player in disease with therapeutic potential

Mcl-1 is essential for the survival of plasma cells

Mcl-1 Is Essential for Germinal Center Formation and B Cell Memory

CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production

Nivolumab plus Brentuximab vedotin +/- bendamustine combination therapy: a safe and effective treatment in pediatric recurrent and refractory classical Hodgkin lymphoma

Multiple Myeloma Relapse Is Associated with Increased NFκB Pathway Activity and Upregulation of the Pro-Survival BCL-2 Protein BFL-1

Dinaciclib synergizes with BH3 mimetics targeting BCL‐2 and BCL‐XL in multiple myeloma cell lines partially dependent on MCL‐1 and in plasma cells from patients

c-Myb Regulates the T-Bet-Dependent Differentiation Program in B Cells to Coordinate Antibody Responses

Identifying clinical response to daratumumab therapy in relapsed/refractory multiple myeloma using a patient‐derived in vitro model

Serpin B9 controls tumor cell killing by CAR T cells

DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice

Through a glass less darkly: apoptosis and the germinal center response to antigen

Monovalent Ligation of the B Cell Receptor Induces Receptor Activation but Fails to Promote Antigen Presentation

Endochondral Bone Regeneration by Non-autologous Mesenchymal Stem Cells

Mice deficient for CD137 ligand are predisposed to develop germinal center–derived B-cell lymphoma

Bridging the gap between scientific discoveries and clinical application at the Utrecht Science Park

Inhibitory pattern recognition receptors

Functional disparities among BCL-2 members in tonsillar and leukemic B-cell subsets assessed by BH3-mimetic profiling

In Vitro Model to Predict Response to Daratumumab Therapy in Relapsed/Refractory Multiple Myeloma

CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17-producing γδ T cell subsets

Targeting B-cell maturation antigen increases sensitivity of multiple myeloma cells to MCL-1 inhibition

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