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Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies in Drug Development: Why, When, and How?

Chemical research in toxicology, 2012-03, Vol.25 (3), p.513-531

2012

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Phase II Dose Selection for Alpha Synuclein–Targeting Antibody Cinpanemab (BIIB054) Based on Target Protein Binding Levels in the Brain

CPT: pharmacometrics and systems pharmacology, 2020-09, Vol.9 (9), p.515-522

2020

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Human radiolabeled mass balance studies: objectives, utilities and limitations

Biopharmaceutics & drug disposition, 2009-05, Vol.30 (4), p.185-203

2009

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Protein proteolysis and the multi-dimensional electrochromatographic separation of histidine-containing peptide fragments on a chip

Journal of Chromatography A, 2003-01, Vol.984 (1), p.97-107

2003

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Capillary electrochromatography of peptides on microfabricated poly(dimethylsiloxane) chips modified by cerium(IV)-catalyzed polymerization

Journal of Chromatography A, 2002-03, Vol.948 (1), p.225-233

2002

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Identification of two novel metabolites of SCH 486757, a nociceptin/orphanin FQ peptide receptor agonist, in humans

Drug metabolism and disposition, 2010-11, Vol.38 (11), p.2067-2074

2010

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A New Quaternary Ammonium Cysteine Analogue as a Trapping Reagent for Reactive Metabolites Screening

Drug metabolism letters, 2014-06, Vol.8 (1), p.36-42

2014

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Tissue distribution of 35S-metabolically labeled neublastin (BG00010) in rats

Journal of pharmaceutical and biomedical analysis, 2020-05, Vol.184, p.113154, Article 113154

2020

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Sampling BIAS at Channel Junctions in Gated Flow Injection on Chips

Analytical chemistry (Washington), 2002-09, Vol.74 (18), p.4835-4840

2002

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Randomized phase I clinical trial of anti–α‐synuclein antibody BIIB054

Movement disorders, 2019-08, Vol.34 (8), p.1154-1163

2019

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Contributions of commercial sorbents to the selectivity in immobilized metal affinity chromatography with Cu(II)

Journal of Chromatography A, 2004-03, Vol.1031 (1), p.87-92

2004

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Nanoliter capillary electrochromatography columns based on collocated monolithic support structures molded in poly(dimethyl siloxane)

Electrophoresis, 2001-09, Vol.22 (17), p.3736-3743

2001

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Histidine-Rich Peptide Selection and Quantification in Targeted Proteomics

Journal of proteome research, 2004-01, Vol.3 (1), p.37-45

2004

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Evaluating Immobilized Metal Affinity Chromatography for the Selection of Histidine-Containing Peptides in Comparative Proteomics

Journal of proteome research, 2003-05, Vol.2 (3), p.321-329

2003

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Application of neutral hydrophobic hypercrosslinked polystyrene to the separation of inorganic anions by ion chromatography

Journal of Chromatography A, 2000-07, Vol.884 (1), p.41-51

2000

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Tissue distribution of 35 S-metabolically labeled neublastin (BG00010) in rats

Journal of pharmaceutical and biomedical analysis, 2020-05, Vol.184, p.113154

2020

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Simultaneous determination of dihydroxybenzenes, aminophenols and phenylenediamines in hair dyes by high-performance liquid chromatography on hypercross-linked polystyrene

Analyst (London), 2000, Vol.125 (7), p.1249-1254

2000

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Correction to Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies in Drug Development: Why, When, and How?

Chemical research in toxicology, 2013-06, Vol.26 (6), p.1023-1023

2013

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A pharmacokinetic and biomarker study of delayed-release dimethyl fumarate in subjects with secondary progressive multiple sclerosis: evaluation of cerebrospinal fluid penetration and the effects on exploratory biomarkers

Multiple sclerosis and related disorders, 2021-06, Vol.51, p.102861, Article 102861

2021

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Quantitative determination of hippuric and benzoic acids in urine by LC–MS/MS using surrogate standards

Journal of pharmaceutical and biomedical analysis, 2010-08, Vol.52 (4), p.534-543

2010

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Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist

Drug metabolism and disposition, 2011-01, Vol.39 (1), p.30-38

2011

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Effect of temperature on retention of alkali and alkaline-earth metal ions on some aminocarboxylic acid functionalised silica based ion exchangers

Journal of Chromatography A, 1998-11, Vol.826 (1), p.15-23

1998

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A new quaternary ammonium cysteine analogue as a trapping reagent for reactive metabolites screening

Drug metabolism letters, 2014, Vol.8 (1), p.36

2014

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Geometric effects of collocated monolithic support structures on separation performance in microfabricated systems

Journal of separation science, 2002-11, Vol.25 (15-17), p.1011-1018

2002

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Geometric effects of collocated monolithic support structures on separation performance in microfabricated systems: Electromigration Methods

Journal of separation science, 2002, Vol.25 (15-17), p.1011-1018

2002

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Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies in Drug Development: Why, When, and How?

Phase II Dose Selection for Alpha Synuclein–Targeting Antibody Cinpanemab (BIIB054) Based on Target Protein Binding Levels in the Brain

Human radiolabeled mass balance studies: objectives, utilities and limitations

Protein proteolysis and the multi-dimensional electrochromatographic separation of histidine-containing peptide fragments on a chip

Capillary electrochromatography of peptides on microfabricated poly(dimethylsiloxane) chips modified by cerium(IV)-catalyzed polymerization

Identification of two novel metabolites of SCH 486757, a nociceptin/orphanin FQ peptide receptor agonist, in humans

A New Quaternary Ammonium Cysteine Analogue as a Trapping Reagent for Reactive Metabolites Screening

Tissue distribution of 35S-metabolically labeled neublastin (BG00010) in rats

Sampling BIAS at Channel Junctions in Gated Flow Injection on Chips

Randomized phase I clinical trial of anti–α‐synuclein antibody BIIB054

Contributions of commercial sorbents to the selectivity in immobilized metal affinity chromatography with Cu(II)

Nanoliter capillary electrochromatography columns based on collocated monolithic support structures molded in poly(dimethyl siloxane)

Histidine-Rich Peptide Selection and Quantification in Targeted Proteomics

Evaluating Immobilized Metal Affinity Chromatography for the Selection of Histidine-Containing Peptides in Comparative Proteomics

Application of neutral hydrophobic hypercrosslinked polystyrene to the separation of inorganic anions by ion chromatography

Tissue distribution of 35 S-metabolically labeled neublastin (BG00010) in rats

Simultaneous determination of dihydroxybenzenes, aminophenols and phenylenediamines in hair dyes by high-performance liquid chromatography on hypercross-linked polystyrene

Correction to Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies in Drug Development: Why, When, and How?

A pharmacokinetic and biomarker study of delayed-release dimethyl fumarate in subjects with secondary progressive multiple sclerosis: evaluation of cerebrospinal fluid penetration and the effects on exploratory biomarkers

Quantitative determination of hippuric and benzoic acids in urine by LC–MS/MS using surrogate standards

Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist

Effect of temperature on retention of alkali and alkaline-earth metal ions on some aminocarboxylic acid functionalised silica based ion exchangers

A new quaternary ammonium cysteine analogue as a trapping reagent for reactive metabolites screening

Geometric effects of collocated monolithic support structures on separation performance in microfabricated systems

Geometric effects of collocated monolithic support structures on separation performance in microfabricated systems: Electromigration Methods

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