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Structural basis for a molecular allosteric control mechanism of cofactor binding to nuclear receptors

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (10), p.E588-E594

2012

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4-Hydroxy-1α,25-Dihydroxyvitamin D3: Synthesis and Structure–Function Study

Biomolecules (Basel, Switzerland), 2024-05, Vol.14 (5), p.551

2024

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Design, synthesis and evaluation of side-chain hydroxylated derivatives of lithocholic acid as potent agonists of the vitamin D receptor (VDR)

Bioorganic chemistry, 2021-10, Vol.115, p.105202-105202, Article 105202

2021

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Structural Basis for the Cell-specific Activities of the NGFI-B and the Nurr1 Ligand-binding Domain

The Journal of biological chemistry, 2005-05, Vol.280 (19), p.19250-19258

2005

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Lithocholic acid-based design of noncalcemic vitamin D receptor agonists

Bioorganic chemistry, 2021-06, Vol.111, p.104878, Article 104878

2021

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The "Phantom Effect" of the Rexinoid LG100754: structural and functional insights

PloS one, 2010-11, Vol.5 (11), p.e15119-e15119

2010

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Rational design of RAR-selective ligands revealed by RARβ crystal stucture

EMBO reports, 2004-09, Vol.5 (9), p.877-882

2004

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Structural and Functional Insights into the Ligand-binding Domain of a Nonduplicated Retinoid X Nuclear Receptor from the Invertebrate Chordate Amphioxus

The Journal of biological chemistry, 2009-01, Vol.284 (3), p.1938-1948

2009

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Silicon Analogues of the Retinoid Agonists TTNPB and 3-Methyl-TTNPB, Disila-TTNPB and Disila-3-methyl-TTNPB: Chemistry and Biology

Chembiochem : a European journal of chemical biology, 2007-09, Vol.8 (14), p.1688-1699

2007

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Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

Nature structural & molecular biology, 2011-05, Vol.18 (5), p.564

2011

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Advances in Vitamin D Receptor Function and Evolution Based on the 3D Structure of the Lamprey Ligand-Binding Domain

Journal of medicinal chemistry, 2022-04, Vol.65 (7), p.5821-5829

2022

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RARβ ligand-binding domain bound to an SRC-1 co-activator peptide: purification, crystallization and preliminary X-ray diffraction analysis

Acta crystallographica. Section D, Biological crystallography., 2004-11, Vol.60 (11), p.2048-2050

2004

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Further Studies on the Highly Active Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D 3 (Calcitriol): Refinement of the Side Chain

Journal of medicinal chemistry, 2023-11, Vol.66 (22), p.15326-15339

2023

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Further Studies on the Highly Active Des-C-Ring and Aromatic-D-Ring Analogues of 1,25-Dihydroxyvitamin D3 (Calcitriol): Refinement of the Side Chain

Journal of medicinal chemistry, 2023-11

2023

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Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain

Journal of medicinal chemistry, 2024-06, Vol.67 (12), p.10386-10400

2024

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Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D 3

Journal of medicinal chemistry, 2022-10, Vol.65 (19), p.13112-13124

2022

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Further Studies on the Highly Active Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3 (Calcitriol): Refinement of the Side Chain

Journal of medicinal chemistry, 2023-11, Vol.66 (22), p.15326-15339

2023

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Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3

Journal of medicinal chemistry, 2022-10, Vol.65 (19), p.13112-13124

2022

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4-Hydroxy-1α,25-Dihydroxyvitamin D[sub.3]: Synthesis and Structure–Function Study

Biomolecules (Basel, Switzerland), 2024-05, Vol.14 (5)

2024

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Modulation of RXR-DNA complex assembly by DNA context

Molecular and cellular endocrinology, 2019-02, Vol.481, p.44-52

2019

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4-Hydroxy-1α,25-Dihydroxyvitamin D 3 : Synthesis and Structure-Function Study

Biomolecules (Basel, Switzerland), 2024-05, Vol.14 (5)

2024

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Investigation of 20S-hydroxyvitamin D3 analogs and their 1α-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities

Scientific reports, 2018-01, Vol.8 (1), p.1-11, Article 1478

2018

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Corrigendum to “Lithocholic acid-based design of noncalcemic vitamin D receptor agonists” [Bioorg. Chem. 111 (2021) 104878]

Bioorganic chemistry, 2023-07, Vol.136, p.106559-106559, Article 106559

2023

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Biological evaluation and synthesis of calcitroic acid

Bioorganic chemistry, 2022-11, Vol.116

2022

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Solution Behavior of the Intrinsically Disordered N‑Terminal Domain of Retinoid X Receptor α in the Context of the Full-Length Protein

Biochemistry (Easton), 2016-03, Vol.55 (12), p.1741-1748

2016

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Structural basis for a molecular allosteric control mechanism of cofactor binding to nuclear receptors

4-Hydroxy-1α,25-Dihydroxyvitamin D3: Synthesis and Structure–Function Study

Design, synthesis and evaluation of side-chain hydroxylated derivatives of lithocholic acid as potent agonists of the vitamin D receptor (VDR)

Structural Basis for the Cell-specific Activities of the NGFI-B and the Nurr1 Ligand-binding Domain

Lithocholic acid-based design of noncalcemic vitamin D receptor agonists

The "Phantom Effect" of the Rexinoid LG100754: structural and functional insights

Rational design of RAR-selective ligands revealed by RARβ crystal stucture

Structural and Functional Insights into the Ligand-binding Domain of a Nonduplicated Retinoid X Nuclear Receptor from the Invertebrate Chordate Amphioxus

Silicon Analogues of the Retinoid Agonists TTNPB and 3-Methyl-TTNPB, Disila-TTNPB and Disila-3-methyl-TTNPB: Chemistry and Biology

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

Advances in Vitamin D Receptor Function and Evolution Based on the 3D Structure of the Lamprey Ligand-Binding Domain

RARβ ligand-binding domain bound to an SRC-1 co-activator peptide: purification, crystallization and preliminary X-ray diffraction analysis

Further Studies on the Highly Active Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D 3 (Calcitriol): Refinement of the Side Chain

Further Studies on the Highly Active Des-C-Ring and Aromatic-D-Ring Analogues of 1,25-Dihydroxyvitamin D3 (Calcitriol): Refinement of the Side Chain

Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain

Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D 3

Further Studies on the Highly Active Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3 (Calcitriol): Refinement of the Side Chain

Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3

4-Hydroxy-1α,25-Dihydroxyvitamin D[sub.3]: Synthesis and Structure–Function Study

Modulation of RXR-DNA complex assembly by DNA context

4-Hydroxy-1α,25-Dihydroxyvitamin D 3 : Synthesis and Structure-Function Study

Investigation of 20S-hydroxyvitamin D3 analogs and their 1α-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities

Corrigendum to “Lithocholic acid-based design of noncalcemic vitamin D receptor agonists” [Bioorg. Chem. 111 (2021) 104878]

Biological evaluation and synthesis of calcitroic acid

Solution Behavior of the Intrinsically Disordered N‑Terminal Domain of Retinoid X Receptor α in the Context of the Full-Length Protein

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