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A comprehensive single cell transcriptional landscape of human hematopoietic progenitors

Nature communications, 2019-06, Vol.10 (1), p.2395-2395, Article 2395

2019

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Dynamics of genetically engineered hematopoietic stem and progenitor cells after autologous transplantation in humans

Nature medicine, 2018-11, Vol.24 (11), p.1683-1690

2018

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A mixed-effects stochastic model reveals clonal dominance in gene therapy safety studies

BMC bioinformatics, 2023-06, Vol.24 (1), p.228-228, Article 228

2023

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In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases

Cell stem cell, 2016-07, Vol.19 (1), p.107-119

2016

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Adaptation of Pseudomonas aeruginosa in Cystic Fibrosis airways influences virulence of Staphylococcus aureus in vitro and murine models of co-infection

PloS one, 2014-03, Vol.9 (3), p.e89614-e89614

2014

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Therapeutic efficacy of intracerebral hematopoietic stem cell gene therapy in an Alzheimer's disease mouse model

Nature communications, 2024-09, Vol.15 (1), p.8024-20, Article 8024

2024

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Gene Expression Profiling of Lymph Node Sub-Capsular Sinus Macrophages in Cancer

Frontiers in immunology, 2021-06, Vol.12, p.672123-672123

2021

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Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans

Nature communications, 2021-03, Vol.12 (1), p.1622-16, Article 1622

2021

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Prostaglandin E2 as transduction enhancer affects competitive engraftment of human hematopoietic stem and progenitor cells

Molecular therapy. Methods & clinical development, 2023-12, Vol.31, p.101131-101131, Article 101131

2023

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Meeting FDA Guidance recommendations for replication-competent virus and insertional oncogenesis testing

Molecular therapy. Methods & clinical development, 2023-03, Vol.28, p.28-39

2023

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Genome-wide discovery of small RNAs in Mycobacterium tuberculosis

PloS one, 2012-12, Vol.7 (12), p.e51950-e51950

2012

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A genome-wide identification analysis of small regulatory RNAs in Mycobacterium tuberculosis by RNA-Seq and conservation analysis

PloS one, 2012-03, Vol.7 (3), p.e32723-e32723

2012

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Preclinical Evaluation of a Novel Lentiviral Vector Driving Lineage-Specific BCL11A Knockdown for Sickle Cell Gene Therapy

Molecular therapy. Methods & clinical development, 2020-06, Vol.17, p.589-600

2020

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Integration profile of retroviral vector in gene therapy treated patients is cell‐specific according to gene expression and chromatin conformation of target cell

EMBO molecular medicine, 2011-02, Vol.3 (2), p.89-101

2011

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237 Epitope engineered hematopoietic stem cells to enable multi-specificity CAR-T cells for acute myeloid leukemia

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A273-A273

2023

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Deletion of the LTR enhancer/promoter has no impact on the integration profile of MLV vectors in human hematopoietic progenitors

PloS one, 2013-01, Vol.8 (1), p.e55721

2013

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Penalized inference of the hematopoietic cell differentiation network via high-dimensional clonal tracking

Applied network science, 2019-12, Vol.4 (1), p.1-26, Article 115

2019

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High-definition mapping of retroviral integration sites defines the fate of allogeneic T cells after donor lymphocyte infusion

PloS one, 2010-12, Vol.5 (12), p.e15688-e15688

2010

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Epitope editing enables targeted immunotherapy of acute myeloid leukaemia

Nature (London), 2023-09, Vol.621 (7978), p.404-414

2023

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Estimated comparative integration hotspots identify different behaviors of retroviral gene transfer vectors

PLoS computational biology, 2011-12, Vol.7 (12), p.e1002292

2011

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Scalable inference of cell differentiation networks in gene therapy clonal tracking studies of haematopoiesis

Bioinformatics (Oxford, England), 2023-10, Vol.39 (10)

2023

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Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome

Science (American Association for the Advancement of Science), 2013-08, Vol.341 (6148), p.865-865

2013

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Chromatin organization at the nuclear pore favours HIV replication

Nature communications, 2015-03, Vol.6 (1), p.6483-6483, Article 6483

2015

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Tracking hematopoietic stem cell evolution in a Wiskott–Aldrich clinical trial

The annals of applied statistics, 2023-09, Vol.17 (3)

2023

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Epitope Edited Hematopoietic Stem Cells to Enable Synergistic Immunotherapy Combinations for Acute Myeloid Leukemia

Blood, 2023-11, Vol.142 (Supplement 1), p.7130-7130

2023

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A comprehensive single cell transcriptional landscape of human hematopoietic progenitors

Dynamics of genetically engineered hematopoietic stem and progenitor cells after autologous transplantation in humans

A mixed-effects stochastic model reveals clonal dominance in gene therapy safety studies

In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases

Adaptation of Pseudomonas aeruginosa in Cystic Fibrosis airways influences virulence of Staphylococcus aureus in vitro and murine models of co-infection

Therapeutic efficacy of intracerebral hematopoietic stem cell gene therapy in an Alzheimer's disease mouse model

Gene Expression Profiling of Lymph Node Sub-Capsular Sinus Macrophages in Cancer

Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans

Prostaglandin E2 as transduction enhancer affects competitive engraftment of human hematopoietic stem and progenitor cells

Meeting FDA Guidance recommendations for replication-competent virus and insertional oncogenesis testing

Genome-wide discovery of small RNAs in Mycobacterium tuberculosis

A genome-wide identification analysis of small regulatory RNAs in Mycobacterium tuberculosis by RNA-Seq and conservation analysis

Preclinical Evaluation of a Novel Lentiviral Vector Driving Lineage-Specific BCL11A Knockdown for Sickle Cell Gene Therapy

Integration profile of retroviral vector in gene therapy treated patients is cell‐specific according to gene expression and chromatin conformation of target cell

237 Epitope engineered hematopoietic stem cells to enable multi-specificity CAR-T cells for acute myeloid leukemia

Deletion of the LTR enhancer/promoter has no impact on the integration profile of MLV vectors in human hematopoietic progenitors

Penalized inference of the hematopoietic cell differentiation network via high-dimensional clonal tracking

High-definition mapping of retroviral integration sites defines the fate of allogeneic T cells after donor lymphocyte infusion

Epitope editing enables targeted immunotherapy of acute myeloid leukaemia

Estimated comparative integration hotspots identify different behaviors of retroviral gene transfer vectors

Scalable inference of cell differentiation networks in gene therapy clonal tracking studies of haematopoiesis

Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome

Chromatin organization at the nuclear pore favours HIV replication

Tracking hematopoietic stem cell evolution in a Wiskott–Aldrich clinical trial

Epitope Edited Hematopoietic Stem Cells to Enable Synergistic Immunotherapy Combinations for Acute Myeloid Leukemia

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