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Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models

Molecular cancer therapeutics, 2020-05, Vol.19 (5), p.1091-1101

2020

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A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies

Molecular cancer therapeutics, 2022-06, Vol.21 (6), p.859-870

2022

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EMD 1214063 and EMD 1204831 Constitute a New Class of Potent and Highly Selective c-Met Inhibitors

Clinical cancer research, 2013-06, Vol.19 (11), p.2941-2951

2013

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brain-specific double-stranded RNA-binding protein Staufen2 is required for dendritic spine morphogenesis

The Journal of cell biology, 2006-01, Vol.172 (2), p.221-231

2006

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Electrophysiological characterization of ATPases in native synaptic vesicles and synaptic plasma membranes

Biochemical journal, 2010-03, Vol.427 (1), p.151-159

2010

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Illuminating a Dark Kinase: Structure-Guided Design, Synthesis, and Evaluation of a Potent Nek1 Inhibitor and Its Effects on the Embryonic Zebrafish Pronephros

Journal of medicinal chemistry, 2022-01, Vol.65 (2), p.1265-1282

2022

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Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors

Bioorganic & medicinal chemistry letters, 2015-04, Vol.25 (7), p.1597-1602

2015

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Abstract 2588: M1774, a novel potent and selective ATR inhibitor, shows antitumor effects as monotherapy and in combination

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.2588-2588

2022

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Abstract 1658: M3814, a novel investigational DNA-PK inhibitor: enhancing the effect of fractionated radiotherapy leading to complete regression of tumors in mice

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1658-1658

2016

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Integration of an In Situ MALDI-Based High-Throughput Screening Process: A Case Study with Receptor Tyrosine Kinase c-MET

SLAS discovery, 2017-12, Vol.22 (10), p.1203-1210

2017

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A Novel Fluorescence Assay for Voltage-Gated Ion Channels Based upon Light Induced Voltage Clamp

Biophysical journal, 2010-01, Vol.98 (3), p.709a-710a

2010

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Molecular Biology of Thermoregulation: Selected Contribution: Role of IL-6 in LPS-induced nuclear STAT3 translocation in sensory circumventricular organs during fever in rats

Journal of applied physiology (1985), 2002-06, Vol.92 (6), p.2657

2002

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Olfactory receptor expressed in ganglia of the autonomic nervous system

Journal of neuroscience research, 2002-04, Vol.68 (2), p.176-184

2002

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A Novel Screening Tool for Voltage-Gated Ion Channels: Light Induced Voltage Clamp

Biophysical journal, 2009-02, Vol.96 (3), p.176a-177a

2009

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Cholinergic signal transduction in the mouse sphenopalatine ganglion

Brain research, 2008-11, Vol.1241, p.42-55

2008

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Influence of systemic treatment with cyclooxygenase inhibitors on lipopolysaccharide-induced fever and circulating levels of cytokines and cortisol in guinea-pigs

Pflügers Archiv, 2002-01, Vol.443 (3), p.411-417

2002

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Automated Higher-Throughput Compound Screening on Ion Channel Targets Based on the Xenopus laevis Oocyte Expression System

Assay and drug development technologies, 2004-10, Vol.2 (5), p.515-524

2004

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Automated higher-throughput compound screening on ion channel targets based on the Xenopus laevis oocyte expression system

Assay and drug development technologies, 2004-10, Vol.2 (5), p.515-524

2004

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Fever induction by localized subcutaneous inflammation in guinea pigs: the role of cytokines and prostaglandins

Journal of applied physiology (1985), 2003-04, Vol.94 (4), p.1395-1402

2003

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Role of IL-6 in LPS-induced nuclear STAT3 translocation in sensory circumventricular organs during fever in rats. Commentary : Molecular biology of thermoregulation

Journal of applied physiology (1985), 2002, Vol.92 (6), p.2656-2666

2002

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Endogenous NO‐Synthase Is Effective as a Modulator of Spinal Thermosensitive Neuronsa

Annals of the New York Academy of Sciences, 1997-03, Vol.813 (1), p.166-175

1997

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Regional specific effects of nitric oxide donors and cGMP on the electrical activity of neurons in the rat spinal cord

Journal of chemical neuroanatomy, 1996-06, Vol.10 (3), p.197-201

1996

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Endogenous NO-Synthase Is Effective as a Modulator of Spinal Thermosensitive Neurons

Annals of the New York Academy of Sciences, 1997-03, Vol.813 (1), p.166-175

1997

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The central pyrogenic action of interleukin-6 is related to nuclear translocation of STAT3 in the anteroventral preoptic area of the rat brain

Journal of thermal biology, 2001-09, Vol.26 (4), p.299-305

2001

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Chapter 3 Spinal neuronal thermosensitivity in vivo and in vitro in relation to hypothalamic neuronal thermosensitivity

Progress in Brain Research, 1998, Vol.115, p.25-47

1998

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Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models

A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies

EMD 1214063 and EMD 1204831 Constitute a New Class of Potent and Highly Selective c-Met Inhibitors

brain-specific double-stranded RNA-binding protein Staufen2 is required for dendritic spine morphogenesis

Electrophysiological characterization of ATPases in native synaptic vesicles and synaptic plasma membranes

Illuminating a Dark Kinase: Structure-Guided Design, Synthesis, and Evaluation of a Potent Nek1 Inhibitor and Its Effects on the Embryonic Zebrafish Pronephros

Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors

Abstract 2588: M1774, a novel potent and selective ATR inhibitor, shows antitumor effects as monotherapy and in combination

Abstract 1658: M3814, a novel investigational DNA-PK inhibitor: enhancing the effect of fractionated radiotherapy leading to complete regression of tumors in mice

Integration of an In Situ MALDI-Based High-Throughput Screening Process: A Case Study with Receptor Tyrosine Kinase c-MET

A Novel Fluorescence Assay for Voltage-Gated Ion Channels Based upon Light Induced Voltage Clamp

Molecular Biology of Thermoregulation: Selected Contribution: Role of IL-6 in LPS-induced nuclear STAT3 translocation in sensory circumventricular organs during fever in rats

Olfactory receptor expressed in ganglia of the autonomic nervous system

A Novel Screening Tool for Voltage-Gated Ion Channels: Light Induced Voltage Clamp

Cholinergic signal transduction in the mouse sphenopalatine ganglion

Influence of systemic treatment with cyclooxygenase inhibitors on lipopolysaccharide-induced fever and circulating levels of cytokines and cortisol in guinea-pigs

Automated Higher-Throughput Compound Screening on Ion Channel Targets Based on the Xenopus laevis Oocyte Expression System

Automated higher-throughput compound screening on ion channel targets based on the Xenopus laevis oocyte expression system

Fever induction by localized subcutaneous inflammation in guinea pigs: the role of cytokines and prostaglandins

Role of IL-6 in LPS-induced nuclear STAT3 translocation in sensory circumventricular organs during fever in rats. Commentary : Molecular biology of thermoregulation

Endogenous NO‐Synthase Is Effective as a Modulator of Spinal Thermosensitive Neuronsa

Regional specific effects of nitric oxide donors and cGMP on the electrical activity of neurons in the rat spinal cord

Endogenous NO-Synthase Is Effective as a Modulator of Spinal Thermosensitive Neurons

The central pyrogenic action of interleukin-6 is related to nuclear translocation of STAT3 in the anteroventral preoptic area of the rat brain

Chapter 3 Spinal neuronal thermosensitivity in vivo and in vitro in relation to hypothalamic neuronal thermosensitivity

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