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Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide

Amino acids, 2007-08, Vol.33 (2), p.231-240

2007

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New SMS mutation leads to a striking reduction in spermine synthase protein function and a severe form of Snyder–Robinson X-linked recessive mental retardation syndrome

Journal of medical genetics, 2008-08, Vol.45 (8), p.539-543

2008

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A missense mutation, p.V132G, in the X-linked spermine synthase gene (SMS) causes Snyder-Robinson syndrome

American journal of medical genetics. Part A, 2009-03, Vol.149A (3), p.328-335

2009

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The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor

Nature structural & molecular biology, 2002-01, Vol.9 (1), p.27-31

2002

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Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy

Cancer research (Chicago, Ill.), 1988-02, Vol.48 (4), p.759-774

PEGG, A. E

1988

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Recent advances in the biochemistry of polyamines in eukaryotes

Biochemical journal, 1986-03, Vol.234 (2), p.249-262

Pegg, A E

1986

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Spermidine/spermine N1‐acetyltransferase — the turning point in polyamine metabolism

The FASEB journal, 1993-05, Vol.7 (8), p.653-661

1993

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Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells

Cancer research (Chicago, Ill.), 2000-09, Vol.60 (18), p.5187-5195

2000

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Polyamines and neoplastic growth

Biochemical Society transactions, 2007-04, Vol.35 (Pt 2), p.295-299

2007

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Transgenic mouse models for studies of the role of polyamines in normal, hypertrophic and neoplastic growth

Biochemical Society transactions, 2003-04, Vol.31 (2), p.356-360

2003

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Induction of apoptosis by excessive polyamine accumulation in ornithine decarboxylase-overproducing L1210 cells

Biochemical journal, 1995-11, Vol.311 ( Pt 3) (3), p.723-727

1995

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Overproduction of ornithine decarboxylase caused by relief of translational repression is associated with neoplastic transformation

Cancer research (Chicago, Ill.), 1994-05, Vol.54 (9), p.2313-2316

1994

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Effect of spermine synthase deficiency on polyamine biosynthesis and content in mice and embryonic fibroblasts, and the sensitivity of fibroblasts to 1,3-bis-(2-chloroethyl)-N-nitrosourea

Biochemical journal, 2000-10, Vol.351 Pt 2 (2), p.439-447

2000

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Repair of DNA containing O6‐alkylguanine

The FASEB journal, 1992-03, Vol.6 (6), p.2302-2310

1992

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Structure of a Human S-Adenosylmethionine Decarboxylase Self-Processing Ester Intermediate and Mechanism of Putrescine Stimulation of Processing As Revealed by the H243A Mutant

Biochemistry (Easton), 2001-08, Vol.40 (32), p.9495-9504

2001

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Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by alpha-difluoromethylornithine. Characterization of sequences at the inhibitor and coenzyme binding sites

The Journal of biological chemistry, 1992-01, Vol.267 (1), p.150-158

1992

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S-adenosylmethionine decarboxylase: structure, function and regulation by polyamines

Biochemical Society transactions, 1998-11, Vol.26 (4), p.580-586

1998

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The Structural Basis for Substrate Specificity and Inhibition of Human S-Adenosylmethionine Decarboxylase

Biochemistry (Easton), 2001-08, Vol.40 (32), p.9484-9494

2001

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Ornithine decarboxylase as an enzyme target for therapy

Pharmacology & therapeutics (Oxford), 1992, Vol.54 (2), p.195-215

1992

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Activity of temozolomide in the treatment of central nervous system tumor xenografts

Cancer research (Chicago, Ill.), 1995-07, Vol.55 (13), p.2853-2857

1995

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Polyamine metabolism and function

American Journal of Physiology: Cell Physiology, 1982-11, Vol.243 (5), p.C212-C221

1982

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Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy

Biochemical journal, 2001-08, Vol.358 (Pt 1), p.25-32

2001

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Ornithine decarboxylase induction in transformation by H-Ras and RhoA

Cancer research (Chicago, Ill.), 1998-07, Vol.58 (13), p.2748-2753

1998

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Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents

Cancer research (Chicago, Ill.), 1991-07, Vol.51 (13), p.3367-3372

1991

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Rapid exchange of subunits of mammalian ornithine decarboxylase

The Journal of biological chemistry, 1994-02, Vol.269 (5), p.3155-3158

1994

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Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide

New SMS mutation leads to a striking reduction in spermine synthase protein function and a severe form of Snyder–Robinson X-linked recessive mental retardation syndrome

A missense mutation, p.V132G, in the X-linked spermine synthase gene (SMS) causes Snyder-Robinson syndrome

The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor

Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy

Recent advances in the biochemistry of polyamines in eukaryotes

Spermidine/spermine N1‐acetyltransferase — the turning point in polyamine metabolism

Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells

Polyamines and neoplastic growth

Transgenic mouse models for studies of the role of polyamines in normal, hypertrophic and neoplastic growth

Induction of apoptosis by excessive polyamine accumulation in ornithine decarboxylase-overproducing L1210 cells

Overproduction of ornithine decarboxylase caused by relief of translational repression is associated with neoplastic transformation

Effect of spermine synthase deficiency on polyamine biosynthesis and content in mice and embryonic fibroblasts, and the sensitivity of fibroblasts to 1,3-bis-(2-chloroethyl)-N-nitrosourea

Repair of DNA containing O6‐alkylguanine

Structure of a Human S-Adenosylmethionine Decarboxylase Self-Processing Ester Intermediate and Mechanism of Putrescine Stimulation of Processing As Revealed by the H243A Mutant

Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by alpha-difluoromethylornithine. Characterization of sequences at the inhibitor and coenzyme binding sites

S-adenosylmethionine decarboxylase: structure, function and regulation by polyamines

The Structural Basis for Substrate Specificity and Inhibition of Human S-Adenosylmethionine Decarboxylase

Ornithine decarboxylase as an enzyme target for therapy

Activity of temozolomide in the treatment of central nervous system tumor xenografts

Polyamine metabolism and function

Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy

Ornithine decarboxylase induction in transformation by H-Ras and RhoA

Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents

Rapid exchange of subunits of mammalian ornithine decarboxylase

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