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ATR Inhibition Potentiates the Radiation-induced Inflammatory Tumor Microenvironment

Clinical cancer research, 2019-06, Vol.25 (11), p.3392-3403

2019

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Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma

Cancer discovery, 2016-03, Vol.6 (3), p.286-299

2016

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Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma

Cancer discovery, 2013-02, Vol.3 (2), p.158-167

2013

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Radiosensitization by the ATR Inhibitor AZD6738 through Generation of Acentric Micronuclei

Molecular cancer therapeutics, 2017-01, Vol.16 (1), p.25-34

2017

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Enhancing anti-tumour innate immunity by targeting the DNA damage response and pattern recognition receptors in combination with radiotherapy

Frontiers in oncology, 2022-08, Vol.12, p.971959-971959

2022

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The D816V Mutation of c-Kit Circumvents a Requirement for Src Family Kinases in c-Kit Signal Transduction

The Journal of biological chemistry, 2009-04, Vol.284 (17), p.11039-11047

2009

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Harnessing radiotherapy-induced NK-cell activity by combining DNA damage–response inhibition and immune checkpoint blockade

Journal for immunotherapy of cancer, 2022-03, Vol.10 (3), p.e004306

2022

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Combined ATR and DNA-PK Inhibition Radiosensitizes Tumor Cells Independently of Their p53 Status

Frontiers in oncology, 2018-07, Vol.8, p.245-245

2018

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Gab2 Is Involved in Differential Phosphoinositide 3-Kinase Signaling by Two Splice Forms of c-Kit

The Journal of biological chemistry, 2008-10, Vol.283 (41), p.27444-27451

2008

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The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism

Molecular therapy. Oncolytics, 2020-03, Vol.16, p.238-249

2020

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Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mutant thyroid cancer

Journal for immunotherapy of cancer, 2020-08, Vol.8 (2), p.e000698

2020

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Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes

Cancer discovery, 2013-04, Vol.3 (4), p.458-469

2013

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CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma

Journal for immunotherapy of cancer, 2022-03, Vol.10 (3), p.e004410

2022

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Grb2 mediates negative regulation of stem cell factor receptor/c-Kit signaling by recruitment of Cbl

Experimental cell research, 2007-11, Vol.313 (18), p.3935-3942

2007

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Inflammatory microenvironment remodelling by tumour cells after radiotherapy

Nature reviews. Cancer, 2020-04, Vol.20 (4), p.203

2020

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The challenge of rehabilitating relocated listed heritage Buildings: Requirements and opportunities

Energy and buildings, 2024-01, Vol.303, p.113577, Article 113577

2024

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Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53

Nature (London), 2014-07, Vol.511 (7510), p.478-482

2014

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SF3B1 mutations are associated with alternative splicing in uveal melanoma

Cancer discovery, 2013-10, Vol.3 (10), p.1122-1129

2013

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BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling

Science signaling, 2014-03, Vol.7 (318), p.ra30

2014

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Abstract 3415: Mutant BRAF small molecule inhibition enhances oncolytic herpes virus immunotherapy through increased immune cell recruitment and activation in melanoma

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.3415-3415

2020

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Abstract B11: Mouse models of melanoma driven by oncogenic NRAS

Molecular cancer research, 2014-12, Vol.12 (12_Supplement), p.B11-B11

2014

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Combination therapy with oncolytic viruses and immune checkpoint inhibitors

Expert opinion on biological therapy, 2020-06, Vol.20 (6), p.635-652

2020

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A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activity

Nature communications, 2015-08, Vol.6 (1), p.8093-8093, Article 8093

2015

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ATR Inhibition Potentiates the Radiation-induced Inflammatory Tumor Microenvironment

Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma

Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma

Radiosensitization by the ATR Inhibitor AZD6738 through Generation of Acentric Micronuclei

Enhancing anti-tumour innate immunity by targeting the DNA damage response and pattern recognition receptors in combination with radiotherapy

The D816V Mutation of c-Kit Circumvents a Requirement for Src Family Kinases in c-Kit Signal Transduction

Harnessing radiotherapy-induced NK-cell activity by combining DNA damage–response inhibition and immune checkpoint blockade

Combined ATR and DNA-PK Inhibition Radiosensitizes Tumor Cells Independently of Their p53 Status

Gab2 Is Involved in Differential Phosphoinositide 3-Kinase Signaling by Two Splice Forms of c-Kit

The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism

Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mutant thyroid cancer

Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes

CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma

Grb2 mediates negative regulation of stem cell factor receptor/c-Kit signaling by recruitment of Cbl

Inflammatory microenvironment remodelling by tumour cells after radiotherapy

The challenge of rehabilitating relocated listed heritage Buildings: Requirements and opportunities

Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53

SF3B1 mutations are associated with alternative splicing in uveal melanoma

BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling

Abstract 3415: Mutant BRAF small molecule inhibition enhances oncolytic herpes virus immunotherapy through increased immune cell recruitment and activation in melanoma

Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma

Abstract B11: Mouse models of melanoma driven by oncogenic NRAS

Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma

Combination therapy with oncolytic viruses and immune checkpoint inhibitors

A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activity

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