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A Selective Transforming Growth Factor-β Ligand Trap Attenuates Pulmonary Hypertension

American journal of respiratory and critical care medicine, 2016-11, Vol.194 (9), p.1140-1151

2016

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Sotatercept analog suppresses inflammation to reverse experimental pulmonary arterial hypertension

Scientific reports, 2022-05, Vol.12 (1), p.7803-7803, Article 7803

2022

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Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis

Nature medicine, 2014-04, Vol.20 (4), p.408

2014

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Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth

The Journal of biological chemistry, 2011-08, Vol.286 (34), p.30034-30046

2011

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Functionally diverse heteromeric traps for ligands of the transforming growth factor-β superfamily

Scientific reports, 2021-09, Vol.11 (1), p.18341-18341, Article 18341

2021

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Endothelial ALK1 Is a Therapeutic Target to Block Metastatic Dissemination of Breast Cancer

Cancer research (Chicago, Ill.), 2015-06, Vol.75 (12), p.2445-2456

2015

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Abstract 14397: Sotatercept Analog RAP-011 Inhibits Right Ventricular Remodeling and Restores Function in a Mouse Model of Pressure Overload

Circulation (New York, N.Y.), 2020-11, Vol.142 (Suppl_3 Suppl 3), p.A14397-A14397

2020

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Administration of a soluble activin type IIB receptor promotes skeletal muscle growth independent of fiber type

Journal of applied physiology (1985), 2010-09, Vol.109 (3), p.635-642

2010

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Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia

Blood, 2014-06, Vol.123 (25), p.3864-3872

2014

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Functional hydraulic sectoring in grapevines as evidenced by sap flow, dye infusion, leaf removal and micro-computed tomography

AoB plants, 2021-04, Vol.13 (2), p.plab003-plab003

2021

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Soluble activin receptor type IIB decoy receptor differentially impacts murine osteogenesis imperfecta muscle function

Muscle & nerve, 2018-02, Vol.57 (2), p.294-304

2018

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Smad2/3‐pathway ligand trap luspatercept enhances erythroid differentiation in murine β‐thalassaemia by increasing GATA‐1 availability

Journal of cellular and molecular medicine, 2020-06, Vol.24 (11), p.6162-6177

2020

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A Soluble Activin Type IIA Receptor Induces Bone Formation and Improves Skeletal Integrity

Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (19), p.7082-7087

2008

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ALK1-Fc inhibits multiple mediators of angiogenesis and suppresses tumor growth

Molecular cancer therapeutics, 2010-02, Vol.9 (2), p.379-388

2010

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A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys

Bone (New York, N.Y.), 2010-04, Vol.46 (4), p.1082-1088

2010

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Skeletal Response to Soluble Activin Receptor Type IIB in Mouse Models of Osteogenesis Imperfecta

Journal of bone and mineral research, 2018-10, Vol.33 (10), p.1760-1772

2018

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Characterization of the Ligand Binding Functionality of the Extracellular Domain of Activin Receptor Type IIB

The Journal of biological chemistry, 2010-07, Vol.285 (27), p.21037-21048

2010

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Designing coastal conservation to deliver ecosystem and human well-being benefits

PloS one, 2017-02, Vol.12 (2), p.e0172458-e0172458

2017

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Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease

Scientific reports, 2019-08, Vol.9 (1), p.11392-14, Article 11392

2019

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Use Of Ankle Immobilization In Evaluating Treatments To Promote Longitudinal Muscle Growth In Mice

Muscle & nerve, 2018-11, Vol.58 (5), p.718-725

2018

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The perceived ecological and human well‐being benefits of ecosystem restoration

People and nature (Hoboken, N.J.), 2024-02, Vol.6 (1), p.4-19

2024

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ActRIIB:ALK4-Fc alleviates muscle dysfunction and comorbidities in murine models of neuromuscular disorders

The Journal of clinical investigation, 2021-02, Vol.131 (4), p.1-16

2021

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Azoxymethane Is a Genetic Background-Dependent Colorectal Tumor Initiator and Promoter in Mice: Effects of Dose, Route, and Diet

Toxicological sciences, 2005-12, Vol.88 (2), p.340-345

2005

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A New Polygenic Model for Nonfamilial Colorectal Cancer Inheritance Based on the Genetic Architecture of the Azoxymethane-Induced Mouse Model

Genetics (Austin), 2020-03, Vol.214 (3), p.691-702

2020

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Epiregulin Is Not Essential for Development of Intestinal Tumors but Is Required for Protection from Intestinal Damage

Molecular and Cellular Biology, 2004-10, Vol.24 (20), p.8907-8916

2004

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A Selective Transforming Growth Factor-β Ligand Trap Attenuates Pulmonary Hypertension

Sotatercept analog suppresses inflammation to reverse experimental pulmonary arterial hypertension

Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis

Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth

Functionally diverse heteromeric traps for ligands of the transforming growth factor-β superfamily

Endothelial ALK1 Is a Therapeutic Target to Block Metastatic Dissemination of Breast Cancer

Abstract 14397: Sotatercept Analog RAP-011 Inhibits Right Ventricular Remodeling and Restores Function in a Mouse Model of Pressure Overload

Administration of a soluble activin type IIB receptor promotes skeletal muscle growth independent of fiber type

Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia

Functional hydraulic sectoring in grapevines as evidenced by sap flow, dye infusion, leaf removal and micro-computed tomography

Soluble activin receptor type IIB decoy receptor differentially impacts murine osteogenesis imperfecta muscle function

Smad2/3‐pathway ligand trap luspatercept enhances erythroid differentiation in murine β‐thalassaemia by increasing GATA‐1 availability

A Soluble Activin Type IIA Receptor Induces Bone Formation and Improves Skeletal Integrity

ALK1-Fc inhibits multiple mediators of angiogenesis and suppresses tumor growth

A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys

Skeletal Response to Soluble Activin Receptor Type IIB in Mouse Models of Osteogenesis Imperfecta

Characterization of the Ligand Binding Functionality of the Extracellular Domain of Activin Receptor Type IIB

Designing coastal conservation to deliver ecosystem and human well-being benefits

Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease

Use Of Ankle Immobilization In Evaluating Treatments To Promote Longitudinal Muscle Growth In Mice

The perceived ecological and human well‐being benefits of ecosystem restoration

ActRIIB:ALK4-Fc alleviates muscle dysfunction and comorbidities in murine models of neuromuscular disorders

Azoxymethane Is a Genetic Background-Dependent Colorectal Tumor Initiator and Promoter in Mice: Effects of Dose, Route, and Diet

A New Polygenic Model for Nonfamilial Colorectal Cancer Inheritance Based on the Genetic Architecture of the Azoxymethane-Induced Mouse Model

Epiregulin Is Not Essential for Development of Intestinal Tumors but Is Required for Protection from Intestinal Damage

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