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Expression, Localisation and Activity of ATP Binding Cassette (ABC) Family of Drug Transporters in Human Amnion Membranes

Placenta (Eastbourne), 2007-08, Vol.28 (8), p.868-877

2007

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The Xenobiotic Transporter ABCG2 Plays a Novel Role in Differentiation of Trophoblast-like BeWo Cells

Placenta (Eastbourne), 2007-04, Vol.28, p.S116-S120

2007

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Pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (AS1404), a novel vascular disrupting agent, in phase I clinical trial

Cancer chemotherapy and pharmacology, 2007-04, Vol.59 (5), p.681-687

2007

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Drug transfer and metabolism by the human placenta

Clinical pharmacokinetics, 2004-01, Vol.43 (8), p.487-514

2004

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Reversible binding of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid to plasma proteins and its distribution into blood cells in various species

Journal of pharmacy and pharmacology, 2001-04, Vol.53 (4), p.463-471

2001

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Interactions of Herbs with Cytochrome P450

Drug metabolism reviews, 2003-01, Vol.35 (1), p.35-98

2003

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Species differences in the metabolism of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in vitro : implications for prediction of metabolic interactions in vivo

Xenobiotica, 2002-02, Vol.32 (2), p.87-107

2002

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Inter-species variation in the metabolism and inhibition of N-[(2′-dimethylamino)ethyl]acridine-4-carboxamide (DACA) by aldehyde oxidase

Biochemical pharmacology, 2000-01, Vol.59 (2), p.161-165

2000

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Identification and reactivity of the major metabolite (ß-1-glucuronide) of the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in humans

Xenobiotica, 2001-05, Vol.31 (5), p.277-293

2001

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Modulation of the pharmacokinetics of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice by thalidomide

Cancer chemotherapy and pharmacology, 2000, Vol.46 (2), p.135-141

2000

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Melphalan penetration of the blood-brain barrier via the neutral amino acid transporter in tumor-bearing brain

Cancer research (Chicago, Ill.), 1992, Vol.52 (1), p.138-143

1992

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Identification of the human liver cytochrome P450 isoenzyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid

Drug metabolism and disposition, 2000-12, Vol.28 (12), p.1449

2000

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Metabolism of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide in cancer patients undergoing a phase I clinical trial

Cancer chemotherapy and pharmacology, 1999, Vol.44 (1), p.51-58

1999

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Plasma pharmacokinetics of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide in a phase I trial

Cancer chemotherapy and pharmacology, 1999, Vol.44 (1), p.45-50

1999

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Metabolism of the experimental antitumor agent acridine carboxamide in the mouse

Drug metabolism and disposition, 1993-05, Vol.21 (3), p.530

1993

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Plasma disposition, metabolism and excretion of the experimental antitumour agent 5,6-dimethylxanthenone-4-acetic acid in the mouse, rat and rabbit

Cancer chemotherapy and pharmacology, 1999, Vol.43 (4), p.323-330

1999

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Pharmacokinetic and toxicity scaling of the antitumor agents amsacrine and CI-921, a new analogue, in mice, rats, rabbits, dogs, and humans

Cancer research (Chicago, Ill.), 1990-05, Vol.50 (9), p.2692-2697

1990

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Effects of Phenytoin on Cognitive‐Motor Performance in Children as a Function of Drug Concentration, Seizure Type, and Time of Medication

Epilepsia (Copenhagen), 1994-01, Vol.35 (1), p.172-180

1994

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Blood‐Brain Barrier Penetration of Felbamate

Epilepsia (Copenhagen), 1992-09, Vol.33 (5), p.944-954

1992

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ABC drug transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast

American journal of physiology. Regulatory, integrative and comparative physiology, 2006-05, Vol.290 (5), p.R1357-R1365

2006

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Effects of Carbamazepine on Psychomotor Performance in Children as a Function of Drug Concentration, Seizure Type, and Time of Medication

Epilepsia (Copenhagen), 1990-01, Vol.31 (1), p.51-60

1990

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Comparison of the blood-brain barrier and liver penetration of acridine antitumor drugs

Cancer chemotherapy and pharmacology, 1992, Vol.29 (6), p.439-444

1992

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Effect of Sodium Valproate on Psychomotor Performance in Children as a Function of Dose, Fluctuations in Concentration, and Diagnosis

Epilepsia (Copenhagen), 1987-03, Vol.28 (2), p.115-124

1987

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Rat hepatocyte-mediated metabolism of the experimental anti-tumour agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide

Xenobiotica, 1993, Vol.23 (4), p.361-371

1993

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Quantitative determination of platinum complexes in human plasma generated from the oral antitumour drug JM216 using directly coupled high-performance liquid chromatography-inductively coupled plasma mass spectrometry without desolvation

Journal of analytical atomic spectrometry, 1999, Vol.14 (6), p.953-956

1999

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Expression, Localisation and Activity of ATP Binding Cassette (ABC) Family of Drug Transporters in Human Amnion Membranes

The Xenobiotic Transporter ABCG2 Plays a Novel Role in Differentiation of Trophoblast-like BeWo Cells

Pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (AS1404), a novel vascular disrupting agent, in phase I clinical trial

Drug transfer and metabolism by the human placenta

Reversible binding of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid to plasma proteins and its distribution into blood cells in various species

Interactions of Herbs with Cytochrome P450

Species differences in the metabolism of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in vitro : implications for prediction of metabolic interactions in vivo

Inter-species variation in the metabolism and inhibition of N-[(2′-dimethylamino)ethyl]acridine-4-carboxamide (DACA) by aldehyde oxidase

Identification and reactivity of the major metabolite (ß-1-glucuronide) of the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in humans

Modulation of the pharmacokinetics of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice by thalidomide

Melphalan penetration of the blood-brain barrier via the neutral amino acid transporter in tumor-bearing brain

Identification of the human liver cytochrome P450 isoenzyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid

Metabolism of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide in cancer patients undergoing a phase I clinical trial

Plasma pharmacokinetics of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide in a phase I trial

Metabolism of the experimental antitumor agent acridine carboxamide in the mouse

Plasma disposition, metabolism and excretion of the experimental antitumour agent 5,6-dimethylxanthenone-4-acetic acid in the mouse, rat and rabbit

Pharmacokinetic and toxicity scaling of the antitumor agents amsacrine and CI-921, a new analogue, in mice, rats, rabbits, dogs, and humans

Effects of Phenytoin on Cognitive‐Motor Performance in Children as a Function of Drug Concentration, Seizure Type, and Time of Medication

Blood‐Brain Barrier Penetration of Felbamate

ABC drug transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast

Effects of Carbamazepine on Psychomotor Performance in Children as a Function of Drug Concentration, Seizure Type, and Time of Medication

Comparison of the blood-brain barrier and liver penetration of acridine antitumor drugs

Effect of Sodium Valproate on Psychomotor Performance in Children as a Function of Dose, Fluctuations in Concentration, and Diagnosis

Rat hepatocyte-mediated metabolism of the experimental anti-tumour agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide

Quantitative determination of platinum complexes in human plasma generated from the oral antitumour drug JM216 using directly coupled high-performance liquid chromatography-inductively coupled plasma mass spectrometry without desolvation

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