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Protein Synthesis Initiation in Eukaryotic Cells

Cold Spring Harbor perspectives in biology, 2018-12, Vol.10 (12), p.a033092

2018

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Regulation of translation initiation factor eIF2B at the hub of the integrated stress response

Wiley interdisciplinary reviews. RNA, 2018-11, Vol.9 (6), p.e1491-n/a

Pavitt, Graham D.

2018

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Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae

Genetics (Austin), 2016-05, Vol.203 (1), p.65-107

2016

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Translational regulation in response to stress in Saccharomyces cerevisiae

Yeast (Chichester, England), 2019-01, Vol.36 (1), p.5-21

2019

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The structural basis of translational control by eIF2 phosphorylation

Nature communications, 2019-05, Vol.10 (1), p.2136-2136, Article 2136

2019

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Interaction of the La-related protein Slf1 with colliding ribosomes maintains translation of oxidative-stress responsive mRNAs

Nucleic acids research, 2023-06, Vol.51 (11), p.5755-5773

2023

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New insights into translational regulation in the endoplasmic reticulum unfolded protein response

Cold Spring Harbor perspectives in biology, 2012-06, Vol.4 (6), p.a012278-a012278

2012

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Global mRNA selection mechanisms for translation initiation

Genome Biology, 2015-01, Vol.16 (1), p.10-10, Article 10

2015

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Enhanced translation initiation factor 4G levels correlate with production levels of monoclonal antibodies in recombinant CHO cell lines

Biochemical journal, 2016-03, Vol.473 (6), p.e11-e13

Pavitt, Graham D

2016

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A new function and complexity for protein translation initiation factor eIF2B

Cell cycle (Georgetown, Tex.), 2014-09, Vol.13 (17), p.2660-2665

2014

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eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation

Nature (London), 2010-05, Vol.465 (7296), p.378-381

2010

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Quantifying the Binding of Fluorescently Labeled Guanine Nucleotides and Initiator tRNA to Eukaryotic Translation Initiation Factor 2

Methods in molecular biology (Clifton, N.J.), 2022, Vol.2428, p.89

2022

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Cytosolic aspartate aminotransferase moonlights as a ribosome-binding modulator of Gcn2 activity during oxidative stress

eLife, 2022-05, Vol.11

2022

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Fail-safe control of translation initiation by dissociation of eIF2α phosphorylated ternary complexes

eLife, 2017-03, Vol.6

2017

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Global Translational Responses to Oxidative Stress Impact upon Multiple Levels of Protein Synthesis

The Journal of biological chemistry, 2006-09, Vol.281 (39), p.29011-29021

2006

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The yeast La related protein Slf1p is a key activator of translation during the oxidative stress response

PLoS genetics, 2015-01, Vol.11 (1), p.e1004903

2015

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Dynamic changes in eIF4F-mRNA interactions revealed by global analyses of environmental stress responses

Genome Biology, 2017-10, Vol.18 (1), p.201-18, Article 201

2017

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Upstream sequence elements direct post-transcriptional regulation of gene expression under stress conditions in yeast

BMC genomics, 2009-01, Vol.10 (1), p.7-7, Article 7

2009

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Overlapping regions of Caf20 mediate its interactions with the mRNA-5′cap-binding protein eIF4E and with ribosomes

Scientific reports, 2021-06, Vol.11 (1), p.1-14, Article 13467

2021

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The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of Translation

PLoS genetics, 2015-05, Vol.11 (5), p.e1005233-e1005233

2015

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Translation factor and RNA binding protein mRNA interactomes support broader RNA regulons for posttranscriptional control

The Journal of biological chemistry, 2023-10, Vol.299 (10), p.105195-105195, Article 105195

2023

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Mutations in SNORD118 cause the cerebral microangiopathy leukoencephalopathy with calcifications and cysts

Nature genetics, 2016-10, Vol.48 (10), p.1185-1192

2016

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Protein synthesis and its control in neuronal cells with a focus on vanishing white matter disease

Biochemical Society transactions, 2009-12, Vol.37 (Pt 6), p.1298-1310

2009

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GTP binding to translation factor eIF2B stimulates its guanine nucleotide exchange activity

iScience, 2021-12, Vol.24 (12), p.103454-103454, Article 103454

2021

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Integrated multi-omics analyses reveal the pleiotropic nature of the control of gene expression by Puf3p

Scientific reports, 2015-10, Vol.5 (1), p.15518-15518, Article 15518

2015

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Protein Synthesis Initiation in Eukaryotic Cells

Regulation of translation initiation factor eIF2B at the hub of the integrated stress response

Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae

Translational regulation in response to stress in Saccharomyces cerevisiae

The structural basis of translational control by eIF2 phosphorylation

Interaction of the La-related protein Slf1 with colliding ribosomes maintains translation of oxidative-stress responsive mRNAs

New insights into translational regulation in the endoplasmic reticulum unfolded protein response

Global mRNA selection mechanisms for translation initiation

Enhanced translation initiation factor 4G levels correlate with production levels of monoclonal antibodies in recombinant CHO cell lines

A new function and complexity for protein translation initiation factor eIF2B

eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation

Quantifying the Binding of Fluorescently Labeled Guanine Nucleotides and Initiator tRNA to Eukaryotic Translation Initiation Factor 2

Cytosolic aspartate aminotransferase moonlights as a ribosome-binding modulator of Gcn2 activity during oxidative stress

Fail-safe control of translation initiation by dissociation of eIF2α phosphorylated ternary complexes

Global Translational Responses to Oxidative Stress Impact upon Multiple Levels of Protein Synthesis

The yeast La related protein Slf1p is a key activator of translation during the oxidative stress response

Dynamic changes in eIF4F-mRNA interactions revealed by global analyses of environmental stress responses

Upstream sequence elements direct post-transcriptional regulation of gene expression under stress conditions in yeast

Overlapping regions of Caf20 mediate its interactions with the mRNA-5′cap-binding protein eIF4E and with ribosomes

The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of Translation

Translation factor and RNA binding protein mRNA interactomes support broader RNA regulons for posttranscriptional control

Mutations in SNORD118 cause the cerebral microangiopathy leukoencephalopathy with calcifications and cysts

Protein synthesis and its control in neuronal cells with a focus on vanishing white matter disease

GTP binding to translation factor eIF2B stimulates its guanine nucleotide exchange activity

Integrated multi-omics analyses reveal the pleiotropic nature of the control of gene expression by Puf3p

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