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Liver-directed gene therapy results in long-term correction of progressive familial intrahepatic cholestasis type 3 in mice

Journal of hepatology, 2019-07, Vol.71 (1), p.153-162

2019

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Therapeutic base editing in the adult liver

Nature reviews. Gastroenterology & hepatology, 2021-09, Vol.18 (9), p.597-598

2021

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A biliary HCO3− umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes

Hepatology (Baltimore, Md.), 2012-01, Vol.55 (1), p.173-183

2012

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Sodium taurocholate cotransporting polypeptide (SLC10A1) deficiency: Conjugated hypercholanemia without a clear clinical phenotype

Hepatology (Baltimore, Md.), 2015-01, Vol.61 (1), p.260-267

2015

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CDC50A is required for aminophospholipid transport and cell fusion in mouse C2C12 myoblasts

Journal of cell science, 2022-03, Vol.135 (5)

2022

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P4 ATPases: flippases in health and disease

International Journal of Molecular Sciences, 2013-04, Vol.14 (4), p.7897-7922

2013

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Bile salt signaling and bile salt-based therapies in cardiometabolic disease

Clinical science (1979), 2024-01, Vol.138 (1), p.1-21

2024

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The P4-ATPase ATP9A is a novel determinant of exosome release

PloS one, 2019-04, Vol.14 (4), p.e0213069-e0213069

2019

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Soluble Adenylyl Cyclase Regulates Bile Salt‐Induced Apoptosis in Human Cholangiocytes

Hepatology (Baltimore, Md.), 2016-08, Vol.64 (2), p.522-534

2016

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Function and pathophysiological importance of ABCB4 (MDR3 P-glycoprotein)

Pflügers Archiv, 2007-02, Vol.453 (5), p.601-610

2007

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Vps33b is crucial for structural and functional hepatocyte polarity

Journal of hepatology, 2017-05, Vol.66 (5), p.1001-1011

2017

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Complementary Functions of the Flippase ATP8B1 and the Floppase ABCB4 in Maintaining Canalicular Membrane Integrity

Gastroenterology (New York, N.Y. 1943), 2011-11, Vol.141 (5), p.1927-1937.e4

2011

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Hepatocanalicular Transport Defects: Pathophysiologic Mechanisms of Rare Diseases

Gastroenterology (New York, N.Y. 1943), 2006-03, Vol.130 (3), p.908-925

2006

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ATP8B1 Deficiency Results in Elevated Mitochondrial Phosphatidylethanolamine Levels and Increased Mitochondrial Oxidative Phosphorylation in Human Hepatoma Cells

International journal of molecular sciences, 2022-10, Vol.23 (20), p.12344

2022

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A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin‐Johnson syndrome

Hepatology (Baltimore, Md.), 1997-06, Vol.25 (6), p.1539-1542

1997

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Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4

Cellular and molecular life sciences : CMLS, 2017-02, Vol.74 (4), p.715-730

2017

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Rescue of defective ATP8B1 trafficking by CFTR correctors as a therapeutic strategy for familial intrahepatic cholestasis

Journal of hepatology, 2016-06, Vol.64 (6), p.1339-1347

2016

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Glycochenodeoxycholate Promotes Liver Fibrosis in Mice with Hepatocellular Cholestasis

Cells (Basel, Switzerland), 2020-01, Vol.9 (2), p.281

2020

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P4 ATPases – The physiological relevance of lipid flipping transporters

FEBS letters, 2010-07, Vol.584 (13), p.2708-2716

2010

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ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes

Hepatology (Baltimore, Md.), 2016-07, Vol.64 (1), p.161-174

2016

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The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease

Biochimica et biophysica acta, 2005-06, Vol.1741 (1), p.11-24

2005

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Activity of the Bile Salt Export Pump (ABCB11) Is Critically Dependent on Canalicular Membrane Cholesterol Content

The Journal of biological chemistry, 2009-04, Vol.284 (15), p.9947-9954

2009

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Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

The Journal of clinical investigation, 1998-04, Vol.101 (7), p.1310-1319

1998

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Amino acid metabolism, transport and signalling in the liver revisited

Biochemical pharmacology, 2022-07, Vol.201, p.115074-115074, Article 115074

2022

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Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport

Hepatology (Baltimore, Md.), 2006-07, Vol.44 (1), p.195-204

2006

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Liver-directed gene therapy results in long-term correction of progressive familial intrahepatic cholestasis type 3 in mice

Therapeutic base editing in the adult liver

A biliary HCO3− umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes

Sodium taurocholate cotransporting polypeptide (SLC10A1) deficiency: Conjugated hypercholanemia without a clear clinical phenotype

CDC50A is required for aminophospholipid transport and cell fusion in mouse C2C12 myoblasts

P4 ATPases: flippases in health and disease

Bile salt signaling and bile salt-based therapies in cardiometabolic disease

The P4-ATPase ATP9A is a novel determinant of exosome release

Soluble Adenylyl Cyclase Regulates Bile Salt‐Induced Apoptosis in Human Cholangiocytes

Function and pathophysiological importance of ABCB4 (MDR3 P-glycoprotein)

Vps33b is crucial for structural and functional hepatocyte polarity

Complementary Functions of the Flippase ATP8B1 and the Floppase ABCB4 in Maintaining Canalicular Membrane Integrity

Hepatocanalicular Transport Defects: Pathophysiologic Mechanisms of Rare Diseases

ATP8B1 Deficiency Results in Elevated Mitochondrial Phosphatidylethanolamine Levels and Increased Mitochondrial Oxidative Phosphorylation in Human Hepatoma Cells

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin‐Johnson syndrome

Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4

Rescue of defective ATP8B1 trafficking by CFTR correctors as a therapeutic strategy for familial intrahepatic cholestasis

Glycochenodeoxycholate Promotes Liver Fibrosis in Mice with Hepatocellular Cholestasis

P4 ATPases – The physiological relevance of lipid flipping transporters

ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes

The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease

Activity of the Bile Salt Export Pump (ABCB11) Is Critically Dependent on Canalicular Membrane Cholesterol Content

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

Amino acid metabolism, transport and signalling in the liver revisited

Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport

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