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Inhibition of HIV Replication by Cyclic and Hairpin PNAs Targeting the HIV-1 TAR RNA Loop

Journal of Nucleic Acids, 2012-01, Vol.2012, p.591025-9

2012

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Thermodynamic studies of a series of homologous HIV-1 TAR RNA ligands reveal that loose binders are stronger Tat competitors than tight ones

Nucleic acids research, 2013-06, Vol.41 (11), p.5851

2013

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Exploring the impact of the side-chain length on peptide/RNA binding eventsElectronic supplementary information (ESI) available: Chemistry: abbreviations, materials and equipment, synthetic procedures for new compounds and their characterization (1H and 13C NMR, HPLC and MS or HRMS). Six figures. See DOI: 10.1039/c7cp03726k

2017-07

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Synthesis and Antiviral Activity of Ethidium−Arginine Conjugates Directed Against the TAR RNA of HIV-1

Journal of medicinal chemistry, 1999-10, Vol.42 (20), p.4042-4053

1999

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Exploring the impact of the side-chain length on peptide/RNA binding events

Physical chemistry chemical physics : PCCP, 2017-07, Vol.19 (28), p.18452-18460

2017

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Deciphering structure-activity relationships in a series of Tat/TAR inhibitors

Journal of biomolecular structure & dynamics, 2016-11, Vol.34 (11), p.2327-2338

2016

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Polyamide Amino Acids trimers as TAR RNA ligands and anti-HIV agents

Bioorganic & medicinal chemistry, 2010-11, Vol.18 (21), p.7432-7438

2010

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Polyamide amino acids: a new class of RNA ligands

Chemical communications (Cambridge, England), 2009-01 (17), p.2302-2304

2009

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Solid-phase synthesis and thermal denaturation study of cyclic PNAs targeting the HIV-1 TAR RNA loop

Bioorganic & medicinal chemistry letters, 2007-11, Vol.17 (21), p.6026-6030

2007

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Cyclic PNA hexamer-based compound: modelling, synthesis and inhibition of the HIV-1 RNA dimerization process

Tetrahedron, 2002-07, Vol.58 (28), p.5675-5687

2002

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Cyclic PNA-based compound directed against HIV-1 TAR RNA: modelling, liquid-phase synthesis and TAR binding

Organic & biomolecular chemistry, 2004-01, Vol.2 (1), p.74-79

2004

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A cyclic PNA-based compound targeting domain IV of HCV IRES RNA inhibits in vitro IRES-dependent translation

Bioorganic & medicinal chemistry, 2005-10, Vol.13 (20), p.5700-5709

2005

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A “Ready-To-Use” fluorescent-labelled-cysteine-TBTP (4-thiobutyltriphenylphosphonium) synthon to investigate the delivery of non-permeable PNA (peptide nucleic acids)-based compounds to cells

Bioorganic chemistry, 2007-08, Vol.35 (4), p.313-326

2007

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The ‘fully protected backbone’ approach as a versatile tool for a new solid-phase PNA synthesis strategy

Tetrahedron letters, 2005-06, Vol.46 (23), p.4081-4085

2005

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Synthesis and cellular uptake of a fluorescently labeled cyclic PNA-based compound

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (17), p.4435-4438

2004

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Liquid-phase synthesis of a cyclic hexameric peptide nucleic acid

Tetrahedron letters, 2001-11, Vol.42 (47), p.8303-8306

2001

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Cyclic PNA-based compound directed against HIV-1 TAR RNA: modelling, liquid-phase synthesis and TAR bindingElectronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/ob/b3/b311775h

Organic & biomolecular chemistry, 2004-12, Vol.2 (1), p.74

2004

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Liquid-phase combinatorial synthesis of diPNA-arginine conjugates

Tetrahedron letters, 2002-02, Vol.43 (9), p.1641-1644

2002

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Creación de un Sistema de Vigilancia para las prácticas odontológicas de la Facultad de Odontología de la UEES

Crea ciencia, 2019-07 (11), p.11-19

2019

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Modelling, synthesis and biological evaluation of an ethidium–arginine conjugate linked to a ribonuclease mimic directed against TAR RNA of HIV-1

European journal of medicinal chemistry, 2002-07, Vol.37 (7), p.573-584

2002

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Liquid-phase synthesis of polyamide nucleic acids (PNA)

Tetrahedron, 1999-02, Vol.55 (7), p.1937-1958

1999

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Liquid phase synthesis of a peptidic nucleic acid dimer

Tetrahedron letters, 1996-02, Vol.37 (9), p.1413-1416

1996

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AZT and AZT-monophosphate Prodrugs Incorporating HIV-protease Substrate Fragment: Synthesis and Evaluation as Specific Drug Delivery Systems

Antiviral chemistry & chemotherapy, 2006, Vol.17 (4), p.193-213

2006

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Fluorinated peptides incorporating a 4-fluoroproline residue as potential inhibitors of HIV protease

Journal of fluorine chemistry, 1997-05, Vol.82 (2), p.125-130

1997

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Synthesis and Biological Activities of New Carbaacyclonucleosides and 1′-Oxaacyclonucleosides Related to Clitocine

Nucleosides, nucleotides & nucleic acids, 2000-03, Vol.19 (3), p.567-584

2000

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Inhibition of HIV Replication by Cyclic and Hairpin PNAs Targeting the HIV-1 TAR RNA Loop

Thermodynamic studies of a series of homologous HIV-1 TAR RNA ligands reveal that loose binders are stronger Tat competitors than tight ones

Synthesis and Antiviral Activity of Ethidium−Arginine Conjugates Directed Against the TAR RNA of HIV-1

Exploring the impact of the side-chain length on peptide/RNA binding events

Deciphering structure-activity relationships in a series of Tat/TAR inhibitors

Polyamide Amino Acids trimers as TAR RNA ligands and anti-HIV agents

Polyamide amino acids: a new class of RNA ligands

Solid-phase synthesis and thermal denaturation study of cyclic PNAs targeting the HIV-1 TAR RNA loop

Cyclic PNA hexamer-based compound: modelling, synthesis and inhibition of the HIV-1 RNA dimerization process

Cyclic PNA-based compound directed against HIV-1 TAR RNA: modelling, liquid-phase synthesis and TAR binding

A cyclic PNA-based compound targeting domain IV of HCV IRES RNA inhibits in vitro IRES-dependent translation

A “Ready-To-Use” fluorescent-labelled-cysteine-TBTP (4-thiobutyltriphenylphosphonium) synthon to investigate the delivery of non-permeable PNA (peptide nucleic acids)-based compounds to cells

The ‘fully protected backbone’ approach as a versatile tool for a new solid-phase PNA synthesis strategy

Synthesis and cellular uptake of a fluorescently labeled cyclic PNA-based compound

Liquid-phase synthesis of a cyclic hexameric peptide nucleic acid

Cyclic PNA-based compound directed against HIV-1 TAR RNA: modelling, liquid-phase synthesis and TAR bindingElectronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/ob/b3/b311775h

Liquid-phase combinatorial synthesis of diPNA-arginine conjugates

Creación de un Sistema de Vigilancia para las prácticas odontológicas de la Facultad de Odontología de la UEES

Modelling, synthesis and biological evaluation of an ethidium–arginine conjugate linked to a ribonuclease mimic directed against TAR RNA of HIV-1

Liquid-phase synthesis of polyamide nucleic acids (PNA)

Liquid phase synthesis of a peptidic nucleic acid dimer

AZT and AZT-monophosphate Prodrugs Incorporating HIV-protease Substrate Fragment: Synthesis and Evaluation as Specific Drug Delivery Systems

Fluorinated peptides incorporating a 4-fluoroproline residue as potential inhibitors of HIV protease

Synthesis and Biological Activities of New Carbaacyclonucleosides and 1′-Oxaacyclonucleosides Related to Clitocine

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