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Biocatalysis for synthesis of pharmaceuticals

Bioorganic & medicinal chemistry, 2018-04, Vol.26 (7), p.1252-1274

Patel, Ramesh N.

2018

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Green Biocatalysis

Patel, Ramesh N

1, 2016

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Biocatalytic synthesis of chiral alcohols and amino acids for development of pharmaceuticals

Biomolecules, 2013-10, Vol.3 (4), p.741-777

Patel, Ramesh N

2013

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Synthesis of chiral pharmaceutical intermediates by biocatalysis

Coordination chemistry reviews, 2008-03, Vol.252 (5), p.659-701

Patel, Ramesh N.

2008

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Biocatalysis: Synthesis of Key Intermediates for Development of Pharmaceuticals

ACS catalysis, 2011-09, Vol.1 (9), p.1056-1074

Patel, Ramesh N

2011

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Microbial/enzymatic synthesis of chiral intermediates for pharmaceuticals

Enzyme and microbial technology, 2002-11, Vol.31 (6), p.804-826

Patel, Ramesh N

2002

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Preparation of (R)-Amines from Racemic Amines with an (S)-Amine Transaminase from Bacillus megaterium

Advanced synthesis & catalysis, 2008-06, Vol.350 (9), p.1367-1375

2008

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Biocatalytic synthesis of intermediates for the synthesis of chiral drug substances

Current Opinion in Biotechnology, 2001-12, Vol.12 (6), p.587-604

Patel, Ramesh N

2001

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Enzymatic Synthesis of Chiral Intermediates for Drug Development

Advanced synthesis & catalysis, 2001-08, Vol.343 (6-7), p.527-546

Patel, Ramesh N.

2001

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Preparation of an Amino Acid Intermediate for the Dipeptidyl Peptidase IV Inhibitor, Saxagliptin, using a Modified Phenylalanine Dehydrogenase

Advanced synthesis & catalysis, 2007-06, Vol.349 (8-9), p.1369-1378

2007

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Biocatalytic Synthesis of Chiral Pharmaceutical Intermediates

Food technology and biotechnology, 2004-10, Vol.42 (4), p.305-325

Patel, R N

2004

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Hydroxylation of l-proline to cis-3-hydroxy- l-proline by recombinant Escherichia coli expressing a synthetic l-proline-3-hydroxylase gene

Enzyme and microbial technology, 2009-12, Vol.45 (6), p.484-490

2009

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TOUR DE PACLITAXEL: Biocatalysis for Semisynthesis

Annual review of microbiology, 1998-01, Vol.52 (1), p.361-395

Patel, Ramesh N

1998

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Enantioselective microbial reduction of substituted acetophenones

Tetrahedron: asymmetry, 2004-04, Vol.15 (8), p.1247-1258

2004

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Chemo-enzymatic synthesis of pharmaceutical intermediates

Expert opinion on drug discovery, 2008-02, Vol.3 (2), p.187-245

Patel, Ramesh N

2008

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Synthesis of ethyl-(3 R,5 S)-dihydroxy-6-benzyloxyhexanoates via diastereo- and enantioselective microbial reduction: Cloning and expression of ketoreductase III from Acinetobacter sp. SC 13874

Enzyme and microbial technology, 2008-12, Vol.43 (7), p.544-549

2008

Volltextzugriff (PDF)

Enzymes for the removal of N-carbobenzyloxy protecting groups from N-carbobenzyloxy-d- and l-amino acids

Journal of molecular catalysis. B, Enzymatic, 2013-01, Vol.85-86, p.56-60

2013

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Enzymatic Reduction of Adamantanones to Chiral Adamantanol Intermediates for the Synthesis of 11-β-Hydroxysteroid Dehydrogenase Inhibitors

Organic process research & development, 2014-08, Vol.18 (8), p.960-968

2014

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Enzymatic Preparation of an (S)-Amino Acid from a Racemic Amino Acid

Organic process research & development, 2011-01, Vol.15 (1), p.241-248

2011

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Purification and Cloning of a Ketoreductase used for the Preparation of Chiral Alcohols

Advanced synthesis & catalysis, 2005-06, Vol.347 (7-8), p.1073-1080

2005

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Microbial transformation of 2-amino-4-methyl-3-nitropyridine

Journal of industrial microbiology & biotechnology, 2012-12, Vol.39 (12), p.1789-1799

2012

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Enzymatic Preparation of a d-Amino Acid from a Racemic Amino Acid or Keto Acid

Organic process research & development, 2008-11, Vol.12 (6), p.1119-1129

2008

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Diastereoselective microbial reduction of ( S)-[3-chloro-2-oxo-1-(phenylmethyl)propyl]carbamic acid, 1,1-dimethylethyl ester

Tetrahedron: asymmetry, 2003-10, Vol.14 (20), p.3105-3109

2003

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Enantioselective microbial reduction of 6-oxo-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione: Cloning and expression of reductases

Enzyme and microbial technology, 2006-11, Vol.39 (7), p.1441-1450

2006

Volltextzugriff (PDF)

Green Processes for the Synthesis of Chiral Intermediates for the Development of Drugs

Green Biocatalysis, 2016, p.1-1

Patel, Ramesh N

2016

Volltextzugriff (PDF)

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Biocatalysis for synthesis of pharmaceuticals

Green Biocatalysis

Biocatalytic synthesis of chiral alcohols and amino acids for development of pharmaceuticals

Synthesis of chiral pharmaceutical intermediates by biocatalysis

Biocatalysis: Synthesis of Key Intermediates for Development of Pharmaceuticals

Microbial/enzymatic synthesis of chiral intermediates for pharmaceuticals

Preparation of (R)-Amines from Racemic Amines with an (S)-Amine Transaminase from Bacillus megaterium

Biocatalytic synthesis of intermediates for the synthesis of chiral drug substances

Enzymatic Synthesis of Chiral Intermediates for Drug Development

Preparation of an Amino Acid Intermediate for the Dipeptidyl Peptidase IV Inhibitor, Saxagliptin, using a Modified Phenylalanine Dehydrogenase

Biocatalytic Synthesis of Chiral Pharmaceutical Intermediates

Hydroxylation of l-proline to cis-3-hydroxy- l-proline by recombinant Escherichia coli expressing a synthetic l-proline-3-hydroxylase gene

TOUR DE PACLITAXEL: Biocatalysis for Semisynthesis

Enantioselective microbial reduction of substituted acetophenones

Chemo-enzymatic synthesis of pharmaceutical intermediates

Synthesis of ethyl-(3 R,5 S)-dihydroxy-6-benzyloxyhexanoates via diastereo- and enantioselective microbial reduction: Cloning and expression of ketoreductase III from Acinetobacter sp. SC 13874

Enzymes for the removal of N-carbobenzyloxy protecting groups from N-carbobenzyloxy-d- and l-amino acids

Enzymatic Reduction of Adamantanones to Chiral Adamantanol Intermediates for the Synthesis of 11-β-Hydroxysteroid Dehydrogenase Inhibitors

Enzymatic Preparation of an (S)-Amino Acid from a Racemic Amino Acid

Purification and Cloning of a Ketoreductase used for the Preparation of Chiral Alcohols

Microbial transformation of 2-amino-4-methyl-3-nitropyridine

Enzymatic Preparation of a d-Amino Acid from a Racemic Amino Acid or Keto Acid

Diastereoselective microbial reduction of ( S)-[3-chloro-2-oxo-1-(phenylmethyl)propyl]carbamic acid, 1,1-dimethylethyl ester

Enantioselective microbial reduction of 6-oxo-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione: Cloning and expression of reductases

Green Processes for the Synthesis of Chiral Intermediates for the Development of Drugs

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