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Intratumoral Heterogeneity in EGFR-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition

Cancer research (Chicago, Ill.), 2015-10, Vol.75 (20), p.4372-4383

2015

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Hypoxia inducible factors regulate the transcription of the sprouty2 gene and expression of the sprouty2 protein

PloS one, 2017-02, Vol.12 (2), p.e0171616-e0171616

2017

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Intermolecular Interactions of Sprouty Proteins and Their Implications in Development and Disease

Molecular pharmacology, 2009-10, Vol.76 (4), p.679-691

2009

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HECT Domain-containing E3 Ubiquitin Ligase Nedd4 Interacts with and Ubiquitinates Sprouty2

The Journal of biological chemistry, 2010-01, Vol.285 (1), p.255-264

2010

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Single transmembrane spanning heterotrimeric g protein-coupled receptors and their signaling cascades

Pharmacological reviews, 2004-09, Vol.56 (3), p.371

Patel, Tarun B

2004

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Regulation of Cellular Levels of Sprouty2 Protein by Prolyl Hydroxylase Domain and von Hippel-Lindau Proteins

The Journal of biological chemistry, 2011-12, Vol.286 (49), p.42027-42036

2011

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Sprouty2 downregulates angiogenesis during mouse skin wound healing

American journal of physiology. Heart and circulatory physiology, 2011-02, Vol.300 (2), p.H459-H467

2011

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A Novel Role of Sprouty 2 in Regulating Cellular Apoptosis

The Journal of biological chemistry, 2008-02, Vol.283 (6), p.3181-3190

2008

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The role of Rak in the regulation of stability and function of BRCA1

Oncotarget, 2017-10, Vol.8 (49), p.86799-86815

2017

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The Tumor Suppressor PTEN Is Necessary for Human Sprouty 2-mediated Inhibition of Cell Proliferation

The Journal of biological chemistry, 2006-02, Vol.281 (8), p.4816-4822

2006

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Regulation of Protein Kinase A Activity by p90 Ribosomal S6 Kinase 1

The Journal of biological chemistry, 2009-11, Vol.284 (48), p.33070-33078

2009

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Sprouty2 in the dorsal hippocampus regulates neurogenesis and stress responsiveness in rats

PloS one, 2015-03, Vol.10 (3), p.e0120693-e0120693

2015

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Sprouty2 Protein Regulates Hypoxia-inducible Factor-α (HIFα) Protein Levels and Transcription of HIFα-responsive Genes

The Journal of biological chemistry, 2016-08, Vol.291 (32), p.16787-16801

2016

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Electroconvulsive Seizures Stimulate Glial Proliferation and Reduce Expression of Sprouty2 within the Prefrontal Cortex of Rats

Biological psychiatry (1969), 2007-09, Vol.62 (5), p.505-512

2007

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Subcellular Localization and Biological Actions of Activated RSK1 Are Determined by Its Interactions with Subunits of Cyclic AMP-Dependent Protein Kinase

Molecular and Cellular Biology, 2006-06, Vol.26 (12), p.4586-4600

2006

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Localization and retention of p90 ribosomal S6 kinase 1 in the nucleus: implications for its function

Molecular biology of the cell, 2012-02, Vol.23 (3), p.503-515

2012

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Anacardic acid inhibits gelatinases through the regulation of Spry2, MMP-14, EMMPRIN and RECK

Experimental cell research, 2016-11, Vol.349 (1), p.139-151

2016

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Sprouty2 protein regulates hypoxia-inducible factor-α (HIFα) protein levels and transcription of HIFα-responsive genes

The Journal of biological chemistry, 2017-02, Vol.292 (7), p.3060-3060

2017

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Regulation of vascular smooth muscle cell proliferation and migration by human sprouty 2

Arteriosclerosis, thrombosis, and vascular biology, 2005-03, Vol.25 (3), p.533

2005

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Sprouty regulates cell migration by inhibiting the activation of Rac1 GTPase

Biochemical and biophysical research communications, 2004-10, Vol.323 (1), p.98-103

2004

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Interactions between the regulatory subunit of type I protein kinase A and p90 ribosomal S6 kinase1 regulate cardiomyocyte apoptosis

Molecular pharmacology, 2014-02, Vol.85 (2), p.357-367

2014

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Protein-tyrosine Phosphatase-1B (PTP1B) Mediates the Anti-migratory Actions of Sprouty

The Journal of biological chemistry, 2003-01, Vol.278 (1), p.284-288

2003

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p90 Ribosomal S6 Kinase 1 (RSK1) and the Catalytic Subunit of Protein Kinase A (PKA) Compete for Binding the Pseudosubstrate Region of PKAR1α: ROLE IN THE REGULATION OF PKA AND RSK1 ACTIVITIES

The Journal of biological chemistry, 2010-03, Vol.285 (10), p.6970-6979

2010

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Histidine Residues 912 and 913 in Protein Associated with Myc Are Necessary for the Inhibition of Adenylyl Cyclase Activity

Molecular pharmacology, 2005-01, Vol.67 (1), p.42-49

2005

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Conditional Stimulation of Type V and VI Adenylyl Cyclases by G Protein βγ Subunits

The Journal of biological chemistry, 2007-01, Vol.282 (1), p.294-302

2007

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Intratumoral Heterogeneity in EGFR-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition

Hypoxia inducible factors regulate the transcription of the sprouty2 gene and expression of the sprouty2 protein

Intermolecular Interactions of Sprouty Proteins and Their Implications in Development and Disease

HECT Domain-containing E3 Ubiquitin Ligase Nedd4 Interacts with and Ubiquitinates Sprouty2

Single transmembrane spanning heterotrimeric g protein-coupled receptors and their signaling cascades

Regulation of Cellular Levels of Sprouty2 Protein by Prolyl Hydroxylase Domain and von Hippel-Lindau Proteins

Sprouty2 downregulates angiogenesis during mouse skin wound healing

A Novel Role of Sprouty 2 in Regulating Cellular Apoptosis

The role of Rak in the regulation of stability and function of BRCA1

The Tumor Suppressor PTEN Is Necessary for Human Sprouty 2-mediated Inhibition of Cell Proliferation

Regulation of Protein Kinase A Activity by p90 Ribosomal S6 Kinase 1

Sprouty2 in the dorsal hippocampus regulates neurogenesis and stress responsiveness in rats

Sprouty2 Protein Regulates Hypoxia-inducible Factor-α (HIFα) Protein Levels and Transcription of HIFα-responsive Genes

Electroconvulsive Seizures Stimulate Glial Proliferation and Reduce Expression of Sprouty2 within the Prefrontal Cortex of Rats

Subcellular Localization and Biological Actions of Activated RSK1 Are Determined by Its Interactions with Subunits of Cyclic AMP-Dependent Protein Kinase

Localization and retention of p90 ribosomal S6 kinase 1 in the nucleus: implications for its function

Anacardic acid inhibits gelatinases through the regulation of Spry2, MMP-14, EMMPRIN and RECK

Sprouty2 protein regulates hypoxia-inducible factor-α (HIFα) protein levels and transcription of HIFα-responsive genes

Regulation of vascular smooth muscle cell proliferation and migration by human sprouty 2

Sprouty regulates cell migration by inhibiting the activation of Rac1 GTPase

Interactions between the regulatory subunit of type I protein kinase A and p90 ribosomal S6 kinase1 regulate cardiomyocyte apoptosis

Protein-tyrosine Phosphatase-1B (PTP1B) Mediates the Anti-migratory Actions of Sprouty

p90 Ribosomal S6 Kinase 1 (RSK1) and the Catalytic Subunit of Protein Kinase A (PKA) Compete for Binding the Pseudosubstrate Region of PKAR1α: ROLE IN THE REGULATION OF PKA AND RSK1 ACTIVITIES

Histidine Residues 912 and 913 in Protein Associated with Myc Are Necessary for the Inhibition of Adenylyl Cyclase Activity

Conditional Stimulation of Type V and VI Adenylyl Cyclases by G Protein βγ Subunits

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