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Genetic drug target validation using Mendelian randomisation

Nature communications, 2020-06, Vol.11 (1), p.3255-12, Article 3255

2020

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Adjustment for index event bias in genome-wide association studies of subsequent events

Nature communications, 2019-04, Vol.10 (1), p.1561-1561, Article 1561

2019

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Sex, Age, and Socioeconomic Differences in Nonfatal Stroke Incidence and Subsequent Major Adverse Outcomes

Stroke (1970), 2021-02, Vol.52 (2), p.396-405

2021

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Sex disparity in subsequent outcomes in survivors of coronary heart disease

Heart (British Cardiac Society), 2022-01, Vol.108 (1), p.37

2022

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Coronary angiographic scoring systems: An evaluation of their equivalence and validity

The American heart journal, 2012-10, Vol.164 (4), p.547-552.e1

2012

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Reproducible disease phenotyping at scale: Example of coronary artery disease in UK Biobank

PloS one, 2022-04, Vol.17 (4), p.e0264828-e0264828

2022

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Defining disease phenotypes using national linked electronic health records: a case study of atrial fibrillation

PloS one, 2014-11, Vol.9 (11), p.e110900-e110900

2014

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Aggregate Risk Score Based on Markers of Inflammation, Cell Stress, and Coagulation Is an Independent Predictor of Adverse Cardiovascular Outcomes

Journal of the American College of Cardiology, 2013-07, Vol.62 (4), p.329-337

2013

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Elevated plasma triglyceride concentration and risk of adverse clinical outcomes in 1.5 million people: a CALIBER linked electronic health record study

Cardiovascular diabetology, 2022-06, Vol.21 (1), p.102-102, Article 102

2022

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Genetic Variants at Chromosome 9p21 and Risk of First Versus Subsequent Coronary Heart Disease Events

Journal of the American College of Cardiology, 2014-06, Vol.63 (21), p.2234-2245

2014

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Soluble Urokinase Plasminogen Activator Receptor Level Is an Independent Predictor of the Presence and Severity of Coronary Artery Disease and of Future Adverse Events

Journal of the American Heart Association, 2014-10, Vol.3 (5), p.e001118-n/a

2014

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Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models

BMJ open, 2020-07, Vol.10 (7), p.e034564-e034564

2020

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Phenogrouping heart failure with preserved or mildly reduced ejection fraction using electronic health record data

BMC cardiovascular disorders, 2024-07, Vol.24 (1), p.1-10, Article 343

2024

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Bleeding in cardiac patients prescribed antithrombotic drugs: electronic health record phenotyping algorithms, incidence, trends and prognosis

BMC medicine, 2019-11, Vol.17 (1), p.206-14, Article 206

2019

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Understanding the role of genetics in hypertension

European heart journal, 2017-08, Vol.38 (29), p.2309-2312

2017

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Routinely measured hematological parameters and prediction of recurrent vascular events in patients with clinically manifest vascular disease

PloS one, 2018-09, Vol.13 (9), p.e0202682-e0202682

2018

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Prognostic Significance of Ventricular Arrhythmias in 13 444 Patients With Acute Coronary Syndrome: A Retrospective Cohort Study Based on Routine Clinical Data (NIHR Health Informatics Collaborative VA-ACS Study)

Journal of the American Heart Association, 2022-03, Vol.11 (6), p.e024260

2022

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Prognostic significance of troponin level in 3121 patients presenting with atrial fibrillation (The NIHR Health Informatics Collaborative TROP-AF study)

Journal of the American Heart Association, 2020-04, Vol.9 (7), p.e013684-e013684

2020

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Genetic Variation at the ADAMTS7 Locus is Associated With Reduced Severity of Coronary Artery Disease

Journal of the American Heart Association, 2017-11, Vol.6 (11), p.n/a

2017

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Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention

Journal of the American College of Cardiology, 2018-10, Vol.72 (16), p.1883-1893

2018

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Will you take the opportunity to assess and manage cardiovascular risk?

Trends in urology & men's health, 2024-05, Vol.15 (3), p.9-13

Patel, Riyaz S

2024

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Prognostic significance of troponin in patients with malignancy (NIHR Health Informatics Collaborative TROP-MALIGNANCY study)

Cardio-oncology (London, England), 2024-07, Vol.10 (1), p.1-8, Article 41

2024

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MicroRNA Expression Profile in CAD Patients and the Impact of ACEI/ARB

Cardiology research and practice, 2011-01, Vol.2011, p.532915-5

2011

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UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER

Journal of the American Medical Informatics Association : JAMIA, 2019-12, Vol.26 (12), p.1545-1559

2019

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Genetic drug target validation using Mendelian randomisation

Adjustment for index event bias in genome-wide association studies of subsequent events

Sex, Age, and Socioeconomic Differences in Nonfatal Stroke Incidence and Subsequent Major Adverse Outcomes

Sex disparity in subsequent outcomes in survivors of coronary heart disease

Coronary angiographic scoring systems: An evaluation of their equivalence and validity

Reproducible disease phenotyping at scale: Example of coronary artery disease in UK Biobank

Defining disease phenotypes using national linked electronic health records: a case study of atrial fibrillation

Aggregate Risk Score Based on Markers of Inflammation, Cell Stress, and Coagulation Is an Independent Predictor of Adverse Cardiovascular Outcomes

Elevated plasma triglyceride concentration and risk of adverse clinical outcomes in 1.5 million people: a CALIBER linked electronic health record study

Genetic Variants at Chromosome 9p21 and Risk of First Versus Subsequent Coronary Heart Disease Events

Soluble Urokinase Plasminogen Activator Receptor Level Is an Independent Predictor of the Presence and Severity of Coronary Artery Disease and of Future Adverse Events

Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models

Phenogrouping heart failure with preserved or mildly reduced ejection fraction using electronic health record data

Bleeding in cardiac patients prescribed antithrombotic drugs: electronic health record phenotyping algorithms, incidence, trends and prognosis

Understanding the role of genetics in hypertension

Routinely measured hematological parameters and prediction of recurrent vascular events in patients with clinically manifest vascular disease

Prognostic Significance of Ventricular Arrhythmias in 13 444 Patients With Acute Coronary Syndrome: A Retrospective Cohort Study Based on Routine Clinical Data (NIHR Health Informatics Collaborative VA-ACS Study)

Prognostic significance of troponin level in 3121 patients presenting with atrial fibrillation (The NIHR Health Informatics Collaborative TROP-AF study)

Genetic Variation at the ADAMTS7 Locus is Associated With Reduced Severity of Coronary Artery Disease

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention

Will you take the opportunity to assess and manage cardiovascular risk?

Prognostic significance of troponin in patients with malignancy (NIHR Health Informatics Collaborative TROP-MALIGNANCY study)

Changes in the investigation and management of suspected myocardial infarction and injury during COVID-19: a multi-centre study using routinely collected healthcare data

MicroRNA Expression Profile in CAD Patients and the Impact of ACEI/ARB

UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER

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