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Selective targeting of the stress chaperome as a therapeutic strategy

Trends in pharmacological sciences (Regular ed.), 2014-11, Vol.35 (11), p.592-603

2014

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Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2

Nature chemical biology, 2013-11, Vol.9 (11), p.677-684

2013

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Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series

Journal of medicinal chemistry, 2013-09, Vol.56 (17), p.6803-6818

2013

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Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer

ACS chemical biology, 2014-08, Vol.9 (8), p.1698-1705

2014

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Structure–Activity Relationship in a Purine-Scaffold Compound Series with Selectivity for the Endoplasmic Reticulum Hsp90 Paralog Grp94

Journal of medicinal chemistry, 2015-05, Vol.58 (9), p.3922-3943

2015

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Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5‑(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1188-1207

2014

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3D QSAR and Molecular Docking Studies of Benzimidazole Derivatives as Hepatitis C Virus NS5B Polymerase Inhibitors

Journal of chemical information and modeling, 2008-01, Vol.48 (1), p.42-55

2008

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Heat Shock Protein 70 Inhibitors. 2. 2,5′-Thiodipyrimidines, 5‑(Phenylthio)pyrimidines, 2‑(Pyridin-3-ylthio)pyrimidines, and 3‑(Phenylthio)pyridines as Reversible Binders to an Allosteric Site on Heat Shock Protein 70

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1208-1224

2014

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About the reaction of aryl fluorides with sodium sulfide: investigation into the selectivity of substitution of fluorobenzonitriles to yield mercaptobenzonitriles via SNAr displacement of fluorine

Tetrahedron letters, 2012-05, Vol.53 (20), p.2548-2551

2012

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Design, synthesis, and evaluation of small molecule Hsp90 probes

Bioorganic & medicinal chemistry, 2011-04, Vol.19 (8), p.2603-2614

2011

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An Efficient Copper-Catalyzed Microwave-Assisted S-Arylation towards the Synthesis of 8-Arylsulfanyl Adenines

Synlett, 2011-12, Vol.2011 (20), p.3008-3012

2011

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Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein

Chemistry & biology, 2013-12, Vol.20 (12), p.1469-1480

2013

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Design, synthesis and determination of antifungal activity of 5(6)-substituted benzotriazoles

European journal of medicinal chemistry, 2010-06, Vol.45 (6), p.2214-2222

2010

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CoMSIA Study on Substituted Aryl Alkanoic Acid Analogs as GPR40 Agonists

Chemical biology & drug design, 2011-05, Vol.77 (5), p.361-372

2011

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Abstract 3895: Rational design of small molecule inhibitors that bind to an allosteric pocket on human heat shock protein 70 (Hsp70)

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.3895-3895

2012

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ChemInform Abstract: Reaction of Aryl Fluorides with Sodium Sulfide: Investigation into the Selectivity of Substitution of Fluorobenzonitriles to Yield Mercaptobenzonitriles via SNAr Displacement of Fluorine

ChemInform, 2012-09, Vol.43 (36), p.no-no

2012

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ChemInform Abstract: An Efficient Copper-Catalyzed Microwave-Assisted S-Arylation Towards the Synthesis of 8-Arylsulfanyl Adenines

ChemInform, 2012-04, Vol.43 (17), p.no-no

2012

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Synthesis and Crystallographic Characterization of 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole: A Crucial Intermediate for the Synthesis of Azole Antifungal Drugs

Journal of chemical crystallography, 2009-12, Vol.39 (12), p.923-926

2009

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Structure based deisgn, synthesis and evaluation of purine scaffold Grp94, ER Hsp90, inhibitors

Patel, Pallav D

2013

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An Unusual Presentation From a Sporadic Partially Acid-Fast Aerobic Actinomycete Resistant to Common Antibiotics

JIM - high impact case reports, 2020-01, Vol.8, p.2324709619899598-2324709619899598

2020

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Calciphylaxis in a Patient on Home Hemodialysis

JIM - high impact case reports, 2020, Vol.8, p.2324709620922718-2324709620922718

2020

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ChemInform Abstract: Reaction of Aryl Fluorides with Sodium Sulfide: Investigation into the Selectivity of Substitution of Fluorobenzonitriles to Yield Mercaptobenzonitriles via S N Ar Displacement of Fluorine

ChemInform, 2012-09, Vol.43 (36)

2012

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ChemInform Abstract: Design, Synthesis and Determination of Antifungal Activity of 5(6)-Substituted Benzotriazoles

ChemInform, 2010-10, Vol.41 (41), p.no-no

2010

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ChemInform Abstract: 3D QSAR and Molecular Docking Studies of Benzimidazole Derivatives as Hepatitis C Virus NS5B Polymerase Inhibitors

ChemInform, 2008-04, Vol.39 (18), p.no-no

2008

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Novel carbazole-stilbene hybrids as multifunctional anti-Alzheimer agents

Bioorganic chemistry, 2020-08, Vol.101, p.103977, Article 103977

2020

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Selective targeting of the stress chaperome as a therapeutic strategy

Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2

Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series

Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer

Structure–Activity Relationship in a Purine-Scaffold Compound Series with Selectivity for the Endoplasmic Reticulum Hsp90 Paralog Grp94

Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5‑(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70

3D QSAR and Molecular Docking Studies of Benzimidazole Derivatives as Hepatitis C Virus NS5B Polymerase Inhibitors

Heat Shock Protein 70 Inhibitors. 2. 2,5′-Thiodipyrimidines, 5‑(Phenylthio)pyrimidines, 2‑(Pyridin-3-ylthio)pyrimidines, and 3‑(Phenylthio)pyridines as Reversible Binders to an Allosteric Site on Heat Shock Protein 70

About the reaction of aryl fluorides with sodium sulfide: investigation into the selectivity of substitution of fluorobenzonitriles to yield mercaptobenzonitriles via SNAr displacement of fluorine

Design, synthesis, and evaluation of small molecule Hsp90 probes

An Efficient Copper-Catalyzed Microwave-Assisted S-Arylation towards the Synthesis of 8-Arylsulfanyl Adenines

Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein

Design, synthesis and determination of antifungal activity of 5(6)-substituted benzotriazoles

CoMSIA Study on Substituted Aryl Alkanoic Acid Analogs as GPR40 Agonists

Abstract 3895: Rational design of small molecule inhibitors that bind to an allosteric pocket on human heat shock protein 70 (Hsp70)

ChemInform Abstract: Reaction of Aryl Fluorides with Sodium Sulfide: Investigation into the Selectivity of Substitution of Fluorobenzonitriles to Yield Mercaptobenzonitriles via SNAr Displacement of Fluorine

ChemInform Abstract: An Efficient Copper-Catalyzed Microwave-Assisted S-Arylation Towards the Synthesis of 8-Arylsulfanyl Adenines

Synthesis and Crystallographic Characterization of 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole: A Crucial Intermediate for the Synthesis of Azole Antifungal Drugs

Structure based deisgn, synthesis and evaluation of purine scaffold Grp94, ER Hsp90, inhibitors

An Unusual Presentation From a Sporadic Partially Acid-Fast Aerobic Actinomycete Resistant to Common Antibiotics

Calciphylaxis in a Patient on Home Hemodialysis

ChemInform Abstract: Reaction of Aryl Fluorides with Sodium Sulfide: Investigation into the Selectivity of Substitution of Fluorobenzonitriles to Yield Mercaptobenzonitriles via S N Ar Displacement of Fluorine

ChemInform Abstract: Design, Synthesis and Determination of Antifungal Activity of 5(6)-Substituted Benzotriazoles

ChemInform Abstract: 3D QSAR and Molecular Docking Studies of Benzimidazole Derivatives as Hepatitis C Virus NS5B Polymerase Inhibitors

Novel carbazole-stilbene hybrids as multifunctional anti-Alzheimer agents

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