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Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation

PloS one, 2016-11, Vol.11 (11), p.e0165909-e0165909

2016

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Inhibitory affinity modulation of FcγRIIA ligand binding by glycosphingolipids by inside-out signaling

Cell reports (Cambridge), 2021-05, Vol.35 (7), p.109142-109142, Article 109142

2021

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SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents

American Journal of Physiology: Cell Physiology, 2004-11, Vol.287 (5), p.C1173-C1183

2004

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A randomized, controlled trial evaluating the efficacy and safety of BTH1677 in combination with bevacizumab, carboplatin, and paclitaxel in first-line treatment of advanced non-small cell lung cancer

Journal for immunotherapy of cancer, 2018-02, Vol.6 (1), p.16-16, Article 16

2018

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Binding of Soluble Yeast β-Glucan to Human Neutrophils and Monocytes is Complement-Dependent

Frontiers in immunology, 2013, Vol.4, p.230-230

2013

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A Phase II Efficacy and Safety, Open-Label, Multicenter Study of Imprime PGG Injection in Combination With Cetuximab in Patients With Stage IV KRAS-Mutant Colorectal Cancer

Clinical colorectal cancer, 2016-09, Vol.15 (3), p.222-227

2016

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Differential regulation of oxidative burst by distinct β-glucan-binding receptors and signaling pathways in human peripheral blood mononuclear cells

Glycobiology (Oxford), 2014-04, Vol.24 (4), p.379-391

2014

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A Phase 2 Efficacy and Safety, Open-label, Multicenter Study of Imprime PGG Injection in Combination with Cetuximab in Patients with Stage IV KRAS-Mutant Colorectal Cancer

Clinical colorectal cancer, 2016-02, Vol.15 (3), p.222-227

2016

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BTH1677 in combination with cetuximab with and without irinotecan in patients with advanced metastatic colorectal cancer

Colorectal cancer, 2016-11, Vol.5 (3), p.95-108

2016

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Kinetics of cellular and cytokine responses in a chimeric mouse model for the study of staphylococcal enterotoxin B pathogenesis

Immunology letters, 2000-01, Vol.71 (1), p.19-26

2000

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Imprime PGG, a yeast β-glucan immunomodulator, has the potential to repolarize human monocyte-derived M2 macrophages to M1 phenotype

Journal for immunotherapy of cancer, 2014-11, Vol.2 (Suppl 3), p.P191-P191

2014

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Therapeutic administration of recombinant human granulocyte colony-stimulating factor accelerates hemopoietic regeneration and enhances survival in a murine model of radiation-induced myelosuppression

International journal of cell cloning, 1990, Vol.8 (2), p.107

1990

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Phase III efficacy and safety of RU-0211, a novel chloride channel activator, for the treatment of constipation

Gastroenterology (New York, N.Y. 1943), 2003-04, Vol.124 (4), p.A48-A48

2003

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SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents

American Journal of Physiology: Cell Physiology, 2004-11, Vol.56 (5), p.C1173-C1183

2004

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Enhanced clearance of a multiple antibiotic resistant Staphylococcus aureus in rats treated with PGG-glucan is associated with increased leukocyte counts and increased neutrophil oxidative burst activity

International journal of immunopharmacology, 1998-11, Vol.20 (11), p.595-614

1998

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Therapeutic efficacy of recombinant interleukin-6 (IL-6) alone and combined with recombinant human IL-3 in a nonhuman primate model of high-dose, sublethal radiation-induced marrow aplasia

Blood, 1994-10, Vol.84 (8), p.2515-2522

1994

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Combined modality radioprotection: The use of glucan and selenium with WR-2721

International journal of radiation oncology, biology, physics, 1990-05, Vol.18 (5), p.1069-1075

1990

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Comparison of interleukin-1 alpha gene expression and protein levels in the murine spleen after lethal and sublethal total-body irradiation

Radiation research, 1995-09, Vol.143 (3), p.320

1995

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Sublethal Gamma Irradiation Increases IL-lα, IL-6, and TNF-α mRNA Levels in Murine Hematopoietic Tissues

Journal of interferon & cytokine research, 1997-09, Vol.17 (9), p.567-572

1997

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Histopathologic Effects of Soluble Glucan and WR-2721, Independently and Combined in C3H/HeN Mice

Proceedings of the Society for Experimental Biology and Medicine, 1992-11, Vol.201 (2), p.180-191

1992

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Immunomodulators and hemopoiesis

Survey of immunologic research, 1983-09, Vol.2 (3), p.237

Patchen, M L

1983

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Radioprotection of mice with interleukin-1: relationship to the number of erythroid and granulocyte-macrophage colony-forming cells

Radiation research, 1990-02, Vol.121 (2), p.220

1990

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Leukotriene-induced radioprotection of hematopoietic stem cells in mice

Radiation research, 1988-02, Vol.113 (2), p.388

1988

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Effects of particulate and soluble (1–3)-β-glucans on Ca2+ influx in NR8383 alveolar macrophages

Immunopharmacology, 1998-07, Vol.40 (1), p.77-89

1998

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Survey of newer biological response modifiers for possible use in radioprotection

Pharmacology & therapeutics (Oxford), 1988, Vol.39 (1), p.243-246

1988

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Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation

Inhibitory affinity modulation of FcγRIIA ligand binding by glycosphingolipids by inside-out signaling

SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents

A randomized, controlled trial evaluating the efficacy and safety of BTH1677 in combination with bevacizumab, carboplatin, and paclitaxel in first-line treatment of advanced non-small cell lung cancer

Binding of Soluble Yeast β-Glucan to Human Neutrophils and Monocytes is Complement-Dependent

A Phase II Efficacy and Safety, Open-Label, Multicenter Study of Imprime PGG Injection in Combination With Cetuximab in Patients With Stage IV KRAS-Mutant Colorectal Cancer

Differential regulation of oxidative burst by distinct β-glucan-binding receptors and signaling pathways in human peripheral blood mononuclear cells

A Phase 2 Efficacy and Safety, Open-label, Multicenter Study of Imprime PGG Injection in Combination with Cetuximab in Patients with Stage IV KRAS-Mutant Colorectal Cancer

BTH1677 in combination with cetuximab with and without irinotecan in patients with advanced metastatic colorectal cancer

Kinetics of cellular and cytokine responses in a chimeric mouse model for the study of staphylococcal enterotoxin B pathogenesis

Imprime PGG, a yeast β-glucan immunomodulator, has the potential to repolarize human monocyte-derived M2 macrophages to M1 phenotype

Therapeutic administration of recombinant human granulocyte colony-stimulating factor accelerates hemopoietic regeneration and enhances survival in a murine model of radiation-induced myelosuppression

Phase III efficacy and safety of RU-0211, a novel chloride channel activator, for the treatment of constipation

SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents

Enhanced clearance of a multiple antibiotic resistant Staphylococcus aureus in rats treated with PGG-glucan is associated with increased leukocyte counts and increased neutrophil oxidative burst activity

Therapeutic efficacy of recombinant interleukin-6 (IL-6) alone and combined with recombinant human IL-3 in a nonhuman primate model of high-dose, sublethal radiation-induced marrow aplasia

Combined modality radioprotection: The use of glucan and selenium with WR-2721

Comparison of interleukin-1 alpha gene expression and protein levels in the murine spleen after lethal and sublethal total-body irradiation

Sublethal Gamma Irradiation Increases IL-lα, IL-6, and TNF-α mRNA Levels in Murine Hematopoietic Tissues

Histopathologic Effects of Soluble Glucan and WR-2721, Independently and Combined in C3H/HeN Mice

Immunomodulators and hemopoiesis

Radioprotection of mice with interleukin-1: relationship to the number of erythroid and granulocyte-macrophage colony-forming cells

Leukotriene-induced radioprotection of hematopoietic stem cells in mice

Effects of particulate and soluble (1–3)-β-glucans on Ca2+ influx in NR8383 alveolar macrophages

Survey of newer biological response modifiers for possible use in radioprotection

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