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Eph-Ephrin Bidirectional Signaling in Physiology and Disease

Cell, 2008-04, Vol.133 (1), p.38-52

Pasquale, Elena B.

2008

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Eph Receptors and Ephrins: Therapeutic Opportunities

Annual review of pharmacology and toxicology, 2015-01, Vol.55 (1), p.465-487

2015

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Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex

Developmental cell, 2020-08, Vol.54 (3), p.302-316.e7

2020

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Eph receptors and ephrins in cancer: bidirectional signalling and beyond

Nature reviews. Cancer, 2010-03, Vol.10 (3), p.165

Pasquale, Elena B

2010

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The EphA2 Receptor Drives Self-Renewal and Tumorigenicity in Stem-like Tumor-Propagating Cells from Human Glioblastomas

Cancer cell, 2012-12, Vol.22 (6), p.765-780

2012

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Eph receptors and ephrins in cancer progression

Nature reviews. Cancer, 2024-01, Vol.24 (1), p.5

Pasquale, Elena B

2024

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Protein kinase A can block EphA2 receptor-mediated cell repulsion by increasing EphA2 S897 phosphorylation

Molecular biology of the cell, 2016-09, Vol.27 (17), p.2757-2770

2016

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Eph receptors and ephrins in neuron-astrocyte communication at synapses

Glia, 2011-11, Vol.59 (11), p.1567-1578

2011

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The SAM domain inhibits EphA2 interactions in the plasma membrane

Biochimica et biophysica acta. Molecular cell research, 2017-01, Vol.1864 (1), p.31-38

2017

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Noncanonical EphA2 Signaling Is a Driver of Tumor-Endothelial Cell Interactions and Metastatic Dissemination in BRAF Inhibitor‒Resistant Melanoma

Journal of investigative dermatology, 2021-04, Vol.141 (4), p.840-851.e4

2021

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Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker

Nature communications, 2021-12, Vol.12 (1), p.7047-7047, Article 7047

2021

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Attenuation of eph receptor kinase activation in cancer cells by coexpressed ephrin ligands

PloS one, 2013-11, Vol.8 (11), p.e81445-e81445

2013

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Targeting the Eph System with Peptides and Peptide Conjugates

Current drug targets, 2015-01, Vol.16 (10), p.1031

2015

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Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport

Proceedings of the National Academy of Sciences - PNAS, 2009-07, Vol.106 (30), p.12524-12529

2009

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The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway

Nature cell biology, 2006-08, Vol.8 (8), p.815-825

2006

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Paradoxes of the EphB4 receptor in cancer

Cancer research (Chicago, Ill.), 2007-05, Vol.67 (9), p.3994-3997

2007

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Cancer Somatic Mutations Disrupt Functions of the EphA3 Receptor Tyrosine Kinase through Multiple Mechanisms

Biochemistry (Easton), 2012-02, Vol.51 (7), p.1464-1475

2012

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'Eph'ective signaling: forward, reverse and crosstalk

Journal of cell science, 2003-07, Vol.116 (Pt 14), p.2823-2832

2003

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EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomers

PloS one, 2014-03, Vol.9 (3), p.e92309-e92309

2014

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EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment

Nature communications, 2022-06, Vol.13 (1), p.3535-3535, Article 3535

2022

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EphA4 receptor regulates dendritic spine remodeling by affecting β1-integrin signaling pathways

The Journal of cell biology, 2007-09, Vol.178 (7), p.1295-1307

2007

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Eph receptor signalling casts a wide net on cell behaviour

Nature reviews. Molecular cell biology, 2005-06, Vol.6 (6), p.462-475

Pasquale, Elena B

2005

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Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor

Biochemical journal, 2012-07, Vol.445 (1), p.47-56

2012

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Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK

Nature communications, 2013, Vol.4 (1), p.1681-1681, Article 1681

2013

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The EphA2 receptor is activated through induction of distinct, ligand-dependent oligomeric structures

Communications biology, 2018-01, Vol.1 (1), p.15-15, Article 15

2018

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Eph-Ephrin Bidirectional Signaling in Physiology and Disease

Eph Receptors and Ephrins: Therapeutic Opportunities

Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex

Eph receptors and ephrins in cancer: bidirectional signalling and beyond

The EphA2 Receptor Drives Self-Renewal and Tumorigenicity in Stem-like Tumor-Propagating Cells from Human Glioblastomas

Eph receptors and ephrins in cancer progression

Protein kinase A can block EphA2 receptor-mediated cell repulsion by increasing EphA2 S897 phosphorylation

Eph receptors and ephrins in neuron-astrocyte communication at synapses

The SAM domain inhibits EphA2 interactions in the plasma membrane

Noncanonical EphA2 Signaling Is a Driver of Tumor-Endothelial Cell Interactions and Metastatic Dissemination in BRAF Inhibitor‒Resistant Melanoma

Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker

Attenuation of eph receptor kinase activation in cancer cells by coexpressed ephrin ligands

Targeting the Eph System with Peptides and Peptide Conjugates

Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport

The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway

Paradoxes of the EphB4 receptor in cancer

Cancer Somatic Mutations Disrupt Functions of the EphA3 Receptor Tyrosine Kinase through Multiple Mechanisms

'Eph'ective signaling: forward, reverse and crosstalk

EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomers

EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment

EphA4 receptor regulates dendritic spine remodeling by affecting β1-integrin signaling pathways

Eph receptor signalling casts a wide net on cell behaviour

Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor

Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK

The EphA2 receptor is activated through induction of distinct, ligand-dependent oligomeric structures

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