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Orexins/Hypocretins and Cancer: A Neuropeptide as Emerging Target

Molecules (Basel, Switzerland), 2021-08, Vol.26 (16), p.4849

2021

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Acinar-to-Ductal Metaplasia (ADM): On the Road to Pancreatic Intraepithelial Neoplasia (PanIN) and Pancreatic Cancer

International journal of molecular sciences, 2023-06, Vol.24 (12), p.9946

2023

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The Orexin receptors: Structural and anti-tumoral properties

Frontiers in endocrinology (Lausanne), 2022-07, Vol.13, p.931970-931970

2022

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Orexins as Novel Therapeutic Targets in Inflammatory and Neurodegenerative Diseases

Frontiers in endocrinology (Lausanne), 2019-10, Vol.10, p.709-709

2019

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The Anti-tumoral Properties of Orexin/Hypocretin Hypothalamic Neuropeptides: An Unexpected Therapeutic Role

Frontiers in endocrinology (Lausanne), 2018-09, Vol.9, p.573-573

2018

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Orexins: A promising target to digestive cancers, inflammation, obesity and metabolism dysfunctions

World journal of gastroenterology : WJG, 2021-11, Vol.27 (44), p.7582-7596

2021

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Acinar-to-Ductal Metaplasia and Pancreatic Cancer

International journal of molecular sciences, 2023-06, Vol.24 (12)

2023

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Crucial role of the orexin‐B C‐terminus in the induction of OX1 receptor‐mediated apoptosis: analysis by alanine scanning, molecular modelling and site‐directed mutagenesis

British journal of pharmacology, 2015-11, Vol.172 (21), p.5211-5223

2015

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Design, characterization and preclinical efficacy of a cationic lipid adjuvant for influenza split vaccine

Vaccine, 2001-02, Vol.19 (13), p.1794-1805

2001

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Crucial role of the orexin‐B C‐terminus in the induction of OX 1 receptor‐mediated apoptosis: analysis by alanine scanning, molecular modelling and site‐directed mutagenesis

British journal of pharmacology, 2015-11, Vol.172 (21), p.5211-5223

2015

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Serine 447 in the Carboxyl Tail of Human VPAC1 Receptor Is Crucial for Agonist-Induced Desensitization but Not Internalization of the Receptor

Molecular pharmacology, 2003-12, Vol.64 (6), p.1565

2003

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Abstract 5299: The C-terminus of orexin plays a crucial role in the cellular apoptosis induction mediated by OX1 receptor

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.5299-5299

2014

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Abstract 4581: Combination treatment of orexin-A and NAB-paclitaxel in pancreas cancer: in vitro and in vivo studies

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4581-4581

2016

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Kallikrein-related peptidase 7 (KLK7) is a proliferative factor that is aberrantly expressed in human colon cancer

Biological chemistry, 2014-09, Vol.395 (9), p.1075

2014

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Sa2023 Importance of the Orexin-B C-Terminal End in the Cellular Apoptosis Induction Mediated by Ox1 Receptor

Gastroenterology (New York, N.Y. 1943), 2013-05, Vol.144 (5), p.S-361-S-362

2013

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Site-directed mutagenesis of human vasoactive intestinal peptide receptor subtypes VIP1 and VIP2: evidence for difference in the structure-function relationship

The Journal of pharmacology and experimental therapeutics, 1998-02, Vol.284 (2), p.744

1998

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Microvasculature alters the dispersion properties of shear waves - a multi-frequency MR elastography study

NMR in biomedicine, 2015-12, Vol.28 (12), p.1763-1771

2015

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Human VPAC1 Receptor Selectivity Filter

The Journal of biological chemistry, 2002-10, Vol.277 (40), p.37016-37022

2002

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Identification of Cytoplasmic Domains of hVPAC1 Receptor Required for Activation of Adenylyl Cyclase

The Journal of biological chemistry, 2003-07, Vol.278 (27), p.24759-24766

2003

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Mo1684 Anti-Inflammatory Properties of the Neuropeptide Orexins in Ulcerative Colitis: A New Promising Therapeutical Molecule

Gastroenterology (New York, N.Y. 1943), 2015-04, Vol.148 (4), p.S-685-S-685

2015

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Microvasculature alters the dispersion properties of shear waves - a multi-frequency MR elastography study: Microvasculature Alters the Dispersion Properties of Shear Waves

NMR in biomedicine, 2015-12, Vol.28 (12), p.1763-1771

2015

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Intestinal cell targeting of a stable recombinant Cu–Zn SOD from Cucumis melo fused to a gliadin peptide

Journal of biotechnology, 2012-05, Vol.159 (1-2), p.99-107

2012

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The Human VPAC1 Receptor

The Journal of biological chemistry, 2001-03, Vol.276 (13), p.10153-10160

2001

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Identification of key residues for interaction of vasoactive intestinal peptide with human VPAC1 and VPAC2 receptors and development of a highly selective VPAC1 receptor agonist. Alanine scanning and molecular modeling of the peptide

The Journal of biological chemistry, 2000-08, Vol.275 (31), p.24003

2000

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The N-Terminal Parts of VIP and Antagonist PG97–269 Physically Interact with Different Regions of the Human VPAC1 Receptor

Journal of molecular neuroscience, 2008-11, Vol.36 (1-3), p.245-248

2008

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Orexins/Hypocretins and Cancer: A Neuropeptide as Emerging Target

Acinar-to-Ductal Metaplasia (ADM): On the Road to Pancreatic Intraepithelial Neoplasia (PanIN) and Pancreatic Cancer

The Orexin receptors: Structural and anti-tumoral properties

Orexins as Novel Therapeutic Targets in Inflammatory and Neurodegenerative Diseases

The Anti-tumoral Properties of Orexin/Hypocretin Hypothalamic Neuropeptides: An Unexpected Therapeutic Role

Orexins: A promising target to digestive cancers, inflammation, obesity and metabolism dysfunctions

Acinar-to-Ductal Metaplasia and Pancreatic Cancer

Crucial role of the orexin‐B C‐terminus in the induction of OX1 receptor‐mediated apoptosis: analysis by alanine scanning, molecular modelling and site‐directed mutagenesis

Design, characterization and preclinical efficacy of a cationic lipid adjuvant for influenza split vaccine

Crucial role of the orexin‐B C‐terminus in the induction of OX 1 receptor‐mediated apoptosis: analysis by alanine scanning, molecular modelling and site‐directed mutagenesis

Serine 447 in the Carboxyl Tail of Human VPAC1 Receptor Is Crucial for Agonist-Induced Desensitization but Not Internalization of the Receptor

Abstract 5299: The C-terminus of orexin plays a crucial role in the cellular apoptosis induction mediated by OX1 receptor

Abstract 4581: Combination treatment of orexin-A and NAB-paclitaxel in pancreas cancer: in vitro and in vivo studies

Kallikrein-related peptidase 7 (KLK7) is a proliferative factor that is aberrantly expressed in human colon cancer

Sa2023 Importance of the Orexin-B C-Terminal End in the Cellular Apoptosis Induction Mediated by Ox1 Receptor

Site-directed mutagenesis of human vasoactive intestinal peptide receptor subtypes VIP1 and VIP2: evidence for difference in the structure-function relationship

Microvasculature alters the dispersion properties of shear waves - a multi-frequency MR elastography study

Human VPAC1 Receptor Selectivity Filter

Identification of Cytoplasmic Domains of hVPAC1 Receptor Required for Activation of Adenylyl Cyclase

Mo1684 Anti-Inflammatory Properties of the Neuropeptide Orexins in Ulcerative Colitis: A New Promising Therapeutical Molecule

Microvasculature alters the dispersion properties of shear waves - a multi-frequency MR elastography study: Microvasculature Alters the Dispersion Properties of Shear Waves

Intestinal cell targeting of a stable recombinant Cu–Zn SOD from Cucumis melo fused to a gliadin peptide

The Human VPAC1 Receptor

Identification of key residues for interaction of vasoactive intestinal peptide with human VPAC1 and VPAC2 receptors and development of a highly selective VPAC1 receptor agonist. Alanine scanning and molecular modeling of the peptide

The N-Terminal Parts of VIP and Antagonist PG97–269 Physically Interact with Different Regions of the Human VPAC1 Receptor

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