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Squaric acid derivatives as VLA-4 integrin antagonists

Bioorganic & medicinal chemistry letters, 2002-04, Vol.12 (7), p.1051-1054

2002

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Discovery and evaluation of N-(triazin-1,3,5-yl) phenylalanine derivatives as VLA-4 integrin antagonists

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (12), p.1591-1594

2002

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Population pharmacokinetics of total and unbound teicoplanin concentrations and dosing simulations in patients with haematological malignancy

Journal of antimicrobial chemotherapy, 2018-04, Vol.73 (4), p.995-1003

2018

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A mechanistic modelling approach for the determination of the mechanisms of inhibition by cyclosporine on the uptake and metabolism of atorvastatin in rat hepatocytes using a high throughput uptake method

Xenobiotica, 2020-04, Vol.50 (4), p.415-426

2020

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Dehydrophenylalanine derivatives as VLA-4 integrin antagonists

Bioorganic & medicinal chemistry letters, 2003-03, Vol.13 (5), p.805-808

2003

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N-(Pyrimidin-4-yl) and N-(Pyridin-2-yl) phenylalanine derivatives as VLA-4 integrin antagonists

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (12), p.1595-1598

2002

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Investigation of the in vitro metabolism profile of a phosphodiesterase-IV inhibitor, CDP-840: leading to structural optimization

Drug metabolism and disposition, 2001-03, Vol.29 (3), p.232

2001

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The PEG Moiety of Certolizumab Pegol is Rapidly Cleared from the Blood of Humans by the Kidneys Once it is Cleaved from the Fabʼ: 1195

The American journal of gastroenterology, 2009-10, Vol.104, p.S442-S443

2009

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4-(1,3-Thiazol-2-yl)morpholine derivatives as inhibitors of phosphoinositide 3-kinase

Bioorganic & medicinal chemistry, 2008-08, Vol.18 (15), p.4316-4320

2008

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Investigation of the Distribution and Elimination of the PEG Component of Certolizumab Pegol in Rats: 1105

The American journal of gastroenterology, 2008-09, Vol.103, p.S431-S432

2008

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Measurement of Urinary Excretion of 40 kDa Polyethylene Glycol (PEG) after Subcutaneous Administration of Certolizumab Pegol in Rats: 964

The American journal of gastroenterology, 2007-09, Vol.102, p.S472-S473

2007

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Discovery and evaluation of potent, tyrosine-based α4β1 integrin antagonists

Bioorganic & medicinal chemistry letters, 2000-05, Vol.10 (9), p.997-999

2000

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F(ab′) 2 molecules made from Escherichia coli produced Fab′ with hinge sequences conferring increased serum survival in an animal model

Journal of immunological methods, 1998-08, Vol.217 (1), p.1-10

1998

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Metabolism of aminotetralin analogues in vivo and by rat hepatocytes

Biochemical Society transactions, 1990-12, Vol.18 (6), p.1200

1990

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ChemInform Abstract: Discovery and Evaluation of Potent, Tyrosine-Based α4β1 Integrin Antagonists

ChemInform, 2000-09, Vol.31 (36), p.no-no

2000

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Synthesis of substituted hydroxybutadiene tricarbonyliron complexes

Journal of the American Chemical Society, 1977-06, Vol.99 (12), p.4070-4075

1977

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Chemistry of substituted hydroxybutadienetricarbonyliron complexes

Journal of the American Chemical Society, 1974-08, Vol.96 (17), p.5602-5604

1974

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Squaric acid derivatives as VLA-4 integrin antagonists

Discovery and evaluation of N-(triazin-1,3,5-yl) phenylalanine derivatives as VLA-4 integrin antagonists

Population pharmacokinetics of total and unbound teicoplanin concentrations and dosing simulations in patients with haematological malignancy

A mechanistic modelling approach for the determination of the mechanisms of inhibition by cyclosporine on the uptake and metabolism of atorvastatin in rat hepatocytes using a high throughput uptake method

Dehydrophenylalanine derivatives as VLA-4 integrin antagonists

N-(Pyrimidin-4-yl) and N-(Pyridin-2-yl) phenylalanine derivatives as VLA-4 integrin antagonists

Investigation of the in vitro metabolism profile of a phosphodiesterase-IV inhibitor, CDP-840: leading to structural optimization

The PEG Moiety of Certolizumab Pegol is Rapidly Cleared from the Blood of Humans by the Kidneys Once it is Cleaved from the Fabʼ: 1195

4-(1,3-Thiazol-2-yl)morpholine derivatives as inhibitors of phosphoinositide 3-kinase

Investigation of the Distribution and Elimination of the PEG Component of Certolizumab Pegol in Rats: 1105

Measurement of Urinary Excretion of 40 kDa Polyethylene Glycol (PEG) after Subcutaneous Administration of Certolizumab Pegol in Rats: 964

Discovery and evaluation of potent, tyrosine-based α4β1 integrin antagonists

F(ab′) 2 molecules made from Escherichia coli produced Fab′ with hinge sequences conferring increased serum survival in an animal model

Metabolism of aminotetralin analogues in vivo and by rat hepatocytes

ChemInform Abstract: Discovery and Evaluation of Potent, Tyrosine-Based α4β1 Integrin Antagonists

Synthesis of substituted hydroxybutadiene tricarbonyliron complexes

Chemistry of substituted hydroxybutadienetricarbonyliron complexes

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