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Combined androgen deprivation therapy and radiation therapy for locally advanced prostate cancer: a randomised, phase 3 trial

The Lancet (British edition), 2011-12, Vol.378 (9809), p.2104-2111

2011

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Early versus delayed treatment of relapsed ovarian cancer (MRC OV05/EORTC 55955): a randomised trial

The Lancet (British edition), 2010-10, Vol.376 (9747), p.1155-1163

2010

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Adjuvant therapy with oral sodium clodronate in locally advanced and metastatic prostate cancer: long-term overall survival results from the MRC PR04 and PR05 randomised controlled trials

The lancet oncology, 2009-09, Vol.10 (9), p.872-876

2009

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Treatment selection in multi-arm multi-stage designs: With application to a postpartum haemorrhage trial

Clinical trials (London, England), 2023-02, Vol.20 (1), p.71-80

2023

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Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial

The Lancet (British edition), 2007-07, Vol.370 (9582), p.143-152

2007

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The DURATIONS randomised trial design: Estimation targets, analysis methods and operating characteristics

Clinical trials (London, England), 2020-12, Vol.17 (6), p.644-653

2020

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Assessing the impact of efficacy stopping rules on the error rates under the multi-arm multi-stage framework

Clinical trials (London, England), 2019-04, Vol.16 (2), p.132-141

2019

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When should factorial designs be used for late-phase randomised controlled trials?

Clinical trials (London, England), 2024-04, Vol.21 (2), p.162-170

2024

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A comparison of different population-level summary measures for randomised trials with time-to-event outcomes, with a focus on non-inferiority trials

Clinical trials (London, England), 2023-12, Vol.20 (6), p.594-602

2023

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Flexible trial design in practice - stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial

Trials, 2012-09, Vol.13 (1), p.168-168, Article 168

2012

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Active symptom control with or without chemotherapy in the treatment of patients with malignant pleural mesothelioma (MS01): a multicentre randomised trial

The Lancet (British edition), 2008-05, Vol.371 (9625), p.1685-1694

2008

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Cardiovascular outcomes in patients with locally advanced and metastatic prostate cancer treated with luteinising-hormone-releasing-hormone agonists or transdermal oestrogen: the randomised, phase 2 MRC PATCH trial (PR09)

The lancet oncology, 2013-04, Vol.14 (4), p.306-316

2013

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Rethinking non-inferiority: a practical trial design for optimising treatment duration

Clinical trials (London, England), 2018-10, Vol.15 (5), p.477-488

2018

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Postoperative radiotherapy for non-small cell lung cancer

Cochrane database of systematic reviews, 2016-10, Vol.10 (10), p.CD002142-CD002142

2016

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Interferon alfa-2a versus combination therapy with interferon alfa-2a, interleukin-2, and fluorouracil in patients with untreated metastatic renal cell carcinoma (MRC RE04/EORTC GU 30012): an open-label randomised trial

The Lancet (British edition), 2010-02, Vol.375 (9715), p.641-648

2010

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The UK Lung Cancer Screening Trial: a pilot randomised controlled trial of low-dose computed tomography screening for the early detection of lung cancer

Health technology assessment (Winchester, England), 2016-05, Vol.20 (40), p.1-146

2016

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Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial

Trials, 2009-06, Vol.10 (1), p.39-39, Article 39

2009

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Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit

Trials, 2011-03, Vol.12 (1), p.81-81, Article 81

2011

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Restricted mean survival time: an alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome

BMC medical research methodology, 2013-12, Vol.13 (1), p.152-152, Article 152

2013

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Adjuvant or early salvage radiotherapy for the treatment of localised and locally advanced prostate cancer: a prospectively planned systematic review and meta-analysis of aggregate data

The Lancet (British edition), 2020-10, Vol.396 (10260), p.1422-1431

2020

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A Phase 3 Trial of Bevacizumab in Ovarian Cancer

The New England journal of medicine, 2011-12, Vol.365 (26), p.2484-2496

2011

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Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy

The New England journal of medicine, 2017-07, Vol.377 (4), p.338-351

2017

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Combined androgen deprivation therapy and radiation therapy for locally advanced prostate cancer: a randomised, phase 3 trial

Early versus delayed treatment of relapsed ovarian cancer (MRC OV05/EORTC 55955): a randomised trial

Adjuvant therapy with oral sodium clodronate in locally advanced and metastatic prostate cancer: long-term overall survival results from the MRC PR04 and PR05 randomised controlled trials

Treatment selection in multi-arm multi-stage designs: With application to a postpartum haemorrhage trial

Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial

Escalated-dose versus standard-dose conformal radiotherapy in prostate cancer: first results from the MRC RT01 randomised controlled trial

The DURATIONS randomised trial design: Estimation targets, analysis methods and operating characteristics

Assessing the impact of efficacy stopping rules on the error rates under the multi-arm multi-stage framework

When should factorial designs be used for late-phase randomised controlled trials?

A comparison of different population-level summary measures for randomised trials with time-to-event outcomes, with a focus on non-inferiority trials

Flexible trial design in practice - stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial

Active symptom control with or without chemotherapy in the treatment of patients with malignant pleural mesothelioma (MS01): a multicentre randomised trial

Celecoxib plus hormone therapy versus hormone therapy alone for hormone-sensitive prostate cancer: first results from the STAMPEDE multiarm, multistage, randomised controlled trial

Cardiovascular outcomes in patients with locally advanced and metastatic prostate cancer treated with luteinising-hormone-releasing-hormone agonists or transdermal oestrogen: the randomised, phase 2 MRC PATCH trial (PR09)

Rethinking non-inferiority: a practical trial design for optimising treatment duration

Postoperative radiotherapy for non-small cell lung cancer

Interferon alfa-2a versus combination therapy with interferon alfa-2a, interleukin-2, and fluorouracil in patients with untreated metastatic renal cell carcinoma (MRC RE04/EORTC GU 30012): an open-label randomised trial

The UK Lung Cancer Screening Trial: a pilot randomised controlled trial of low-dose computed tomography screening for the early detection of lung cancer

Design and implementation of an international, multi-arm, multi-stage platform master protocol for trials of novel SARS-CoV-2 antiviral agents: Therapeutics for Inpatients with COVID-19 (TICO/ACTIV-3)

Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial

Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit

Restricted mean survival time: an alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome

Adjuvant or early salvage radiotherapy for the treatment of localised and locally advanced prostate cancer: a prospectively planned systematic review and meta-analysis of aggregate data

A Phase 3 Trial of Bevacizumab in Ovarian Cancer

Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy

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