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Gel-forming mucins form distinct morphologic structures in airways

Proceedings of the National Academy of Sciences - PNAS, 2017-06, Vol.114 (26), p.6842-6847

2017

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Relationships among CFTR expression, HCO3- secretion, and host defense may inform gene- and cell-based cystic fibrosis therapies

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (19), p.5382-5387

2016

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Identification of potent and selective MTH1 inhibitors

Bioorganic & medicinal chemistry letters, 2016-03, Vol.26 (6), p.1503-1507

2016

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Discovery of 6‑[(3S,4S)‑4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methyl-3,4-dihydropyrimidin-4-one (IACS-15414), a Potent and Orally Bioavailable SHP2 Inhibitor

Journal of medicinal chemistry, 2021-10, Vol.64 (20), p.15141-15169

2021

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Multisite Verification of a Targeted CFTR Polymerase Chain Reaction/Capillary Electrophoresis Assay That Evaluates Pathogenic Variants Across Diverse Ethnic and Ancestral Groups

Archives of pathology & laboratory medicine (1976), 2024-01

2024

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Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme

Journal of medicinal chemistry, 2021-08, Vol.64 (15), p.11302-11329

2021

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Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.9888-9911

2020

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P514: High-resolution analysis of pathogenic trinucleotide and hexanucleotide repeats, copy number changes, SNVs and INDELs using flexible, easy-to-use fragment sizing instrumentation

Genetics in Medicine Open, 2023, Vol.1 (1), p.100561, Article 100561

2023

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One-pot synthesis of iron oxide mesoporous silica core/shell nanocomposites

Microporous and mesoporous materials, 2015-03, Vol.204, p.173-179

2015

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Combined Turmeric, Vitamin C, and Vitamin D Ready-to-Drink Supplements Reduce Upper Respiratory Illness Symptoms and Gastrointestinal Discomfort in Elite Male Football Players

Nutrients, 2024-01, Vol.16 (2), p.243

2024

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Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib

Cancer research (Chicago, Ill.), 2020-11, Vol.80 (21), p.4840-4853

2020

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P620: A PCR/nanopore assay for accurate variant detection in hard-to-decipher carrier screening genes with automated analysis software

Genetics in Medicine Open, 2024, Vol.2, p.101526, Article 101526

2024

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Uranium Attenuated by a Wetland 50 Years after Release into a Stream

ACS earth and space chemistry, 2020-08, Vol.4 (8), p.1360-1366

2020

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Analysis of neptunium oxides produced through modified direct denitration

Journal of nuclear materials, 2023-12, Vol.587 (C), p.154704, Article 154704

2023

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Analysis of neptunium oxides produced through modified direct denitration

Journal of nuclear materials, 2023-08, Vol.587

2023

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Uranium partitioning from contaminated wetland soil to aqueous and suspended iron-floc phases: Implications of dynamic hydrologic conditions on contaminant release

Geochimica et cosmochimica acta, 2022-02, Vol.318, p.292-304

2022

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Comparing the Accuracy of Mini-BAL to Bronchoscopic BAL in the Diagnosis of Pneumonia Among Ventilated Patients: A Systematic Literature Review

Journal of Intensive Care Medicine, 2023-12, Vol.38 (12), p.8850666231193379-1107

2023

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HIV‐1 Matrix Protein Interactions with Cellular tRNAs

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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EFFECT OF HIGH- VS LOW-DOSE OF DEXAMETHASONE ON INCIDENCE OF HOSPITAL-ACQUIRED INFECTIONS IN ACUTE HYPOXEMIC RESPIRATORY FAILURE IN SARS COV-2 PNEUMONIA

Chest, 2022-10, Vol.162 (4), p.A674-A675

2022

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Natural attenuation of uranium in a fluvial Wetland: Importance of hydrology and speciation

Applied geochemistry, 2023-08, Vol.155, p.105718, Article 105718

2023

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Relationships among CFTR expression, HCO 3 − secretion, and host defense may inform gene- and cell-based cystic fibrosis therapies

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (19), p.5382-5387

2016

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Abstract 3277: IACS-9779, a development candidate that inhibits 2,3-dioxygenase (IDO) activity by blocking heme incorporation into IDO apoenzyme

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3277-3277

2019

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Allosteric SHP2 inhibitor IACS-13909 overcomes EGFR-dependent and EGFR-independent resistance mechanisms towards osimertinib

Cancer research (Chicago, Ill.), 2020-09, Vol.80 (21), p.4840-4853

2020

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Abstract LB-071: Discovery of an imidazopyridine series of potent human IDO1 inhibitors with robust target engagement in a preclinical tumor model

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.LB-071-LB-071

2018

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Abstract C036: Discovery of IACS-13909, an allosteric SHP2 inhibitor that overcomes multiple mechanisms underlying osimertinib resistance

Molecular cancer therapeutics, 2019-12, Vol.18 (12_Supplement), p.C036-C036

2019

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Gel-forming mucins form distinct morphologic structures in airways

Relationships among CFTR expression, HCO3- secretion, and host defense may inform gene- and cell-based cystic fibrosis therapies

Identification of potent and selective MTH1 inhibitors

Discovery of 6‑[(3S,4S)‑4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methyl-3,4-dihydropyrimidin-4-one (IACS-15414), a Potent and Orally Bioavailable SHP2 Inhibitor

Multisite Verification of a Targeted CFTR Polymerase Chain Reaction/Capillary Electrophoresis Assay That Evaluates Pathogenic Variants Across Diverse Ethnic and Ancestral Groups

Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme

Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R

P514: High-resolution analysis of pathogenic trinucleotide and hexanucleotide repeats, copy number changes, SNVs and INDELs using flexible, easy-to-use fragment sizing instrumentation

One-pot synthesis of iron oxide mesoporous silica core/shell nanocomposites

Combined Turmeric, Vitamin C, and Vitamin D Ready-to-Drink Supplements Reduce Upper Respiratory Illness Symptoms and Gastrointestinal Discomfort in Elite Male Football Players

Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib

P620: A PCR/nanopore assay for accurate variant detection in hard-to-decipher carrier screening genes with automated analysis software

Uranium Attenuated by a Wetland 50 Years after Release into a Stream

Analysis of neptunium oxides produced through modified direct denitration

Analysis of neptunium oxides produced through modified direct denitration

Uranium partitioning from contaminated wetland soil to aqueous and suspended iron-floc phases: Implications of dynamic hydrologic conditions on contaminant release

Comparing the Accuracy of Mini-BAL to Bronchoscopic BAL in the Diagnosis of Pneumonia Among Ventilated Patients: A Systematic Literature Review

HIV‐1 Matrix Protein Interactions with Cellular tRNAs

EFFECT OF HIGH- VS LOW-DOSE OF DEXAMETHASONE ON INCIDENCE OF HOSPITAL-ACQUIRED INFECTIONS IN ACUTE HYPOXEMIC RESPIRATORY FAILURE IN SARS COV-2 PNEUMONIA

Natural attenuation of uranium in a fluvial Wetland: Importance of hydrology and speciation

Relationships among CFTR expression, HCO 3 − secretion, and host defense may inform gene- and cell-based cystic fibrosis therapies

Abstract 3277: IACS-9779, a development candidate that inhibits 2,3-dioxygenase (IDO) activity by blocking heme incorporation into IDO apoenzyme

Allosteric SHP2 inhibitor IACS-13909 overcomes EGFR-dependent and EGFR-independent resistance mechanisms towards osimertinib

Abstract LB-071: Discovery of an imidazopyridine series of potent human IDO1 inhibitors with robust target engagement in a preclinical tumor model

Abstract C036: Discovery of IACS-13909, an allosteric SHP2 inhibitor that overcomes multiple mechanisms underlying osimertinib resistance

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