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Label-free target identification using in-gel fluorescence difference via thermal stability shift

Chemical science (Cambridge), 2017-02, Vol.8 (2), p.1127-1133

2017

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Spatial snapshots of amyloid precursor protein intramembrane processing via early endosome proteomics

Nature communications, 2022-10, Vol.13 (1), p.6112-6112, Article 6112

2022

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Recent advances in identifying protein targets in drug discovery

Cell chemical biology, 2021-03, Vol.28 (3), p.394-423

2021

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Label-free target identification reveals oxidative DNA damage as the mechanism of a selective cytotoxic agent

Chemical science (Cambridge), 2019-03, Vol.10 (12), p.3449-3458

2019

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Label-free target identification in drug discovery via phenotypic screening

Current opinion in chemical biology, 2019-06, Vol.50, p.66-72

2019

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Label-free target identification reveals oxidative DNA damage as the mechanism of a selective cytotoxic agentElectronic supplementary information (ESI) available. See DOI: 10.1039/c8sc05465g

2019-03

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Label-free target identification reveals oxidative DNA damage as the mechanism of a selective cytotoxic agent† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc05465g

Chemical science (Cambridge), 2019-02, Vol.10 (12), p.3449-3458

2019

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Discovery of a Small-Molecule Inhibitor of Protein–MicroRNA Interaction Using Binding Assay with a Site-Specifically Labeled Lin28

Journal of the American Chemical Society, 2016-10, Vol.138 (41), p.13630-13638

2016

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Systematic analysis of nonprogrammed frameshift suppression in E. coli via translational tiling proteomics

Proceedings of the National Academy of Sciences - PNAS, 2024-02, Vol.121 (6), p.e2317453121

2024

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Phenotype-based screening rediscovered benzopyran-embedded microtubule inhibitors as anti-neuroinflammatory agents by modulating the tubulin-p65 interaction

Experimental & molecular medicine, 2022-12, Vol.54 (12), p.2200-2209

2022

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Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cells

Chemical communications (Cambridge, England), 2016-04, Vol.52 (34), p.5828-5831

2016

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Phenotype-based discovery of a HeLa-specific cytotoxic molecule that downregulates HPV-mediated signaling pathways via oxidative damage

Organic & biomolecular chemistry, 2019-08, Vol.17 (31), p.7388-7397

2019

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Phenotype-based discovery of a HeLa-specific cytotoxic molecule that downregulates HPV-mediated signaling pathways oxidative damage

Organic & biomolecular chemistry, 2019-08, Vol.17 (31), p.7388-7397

2019

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Label-free target identification using in-gel fluorescence difference via thermal stability shiftElectronic supplementary information (ESI) available: Experimental details, NMR spectra, and other materials. See DOI: 10.1039/c6sc03238a

2017-01

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Label-free target identification using in-gel fluorescence difference via thermal stability shift† †Electronic supplementary information (ESI) available: Experimental details, NMR spectra, and other materials. See DOI: 10.1039/c6sc03238a Click here for additional data file

Chemical science (Cambridge), 2016-09, Vol.8 (2), p.1127-1133

2016

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Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cellsElectronic supplementary information (ESI) available: Synthetic procedures, spectroscopic data of all new compounds, and procedures for biological experiment. See DOI: 10.1039/c6cc01426g

2016-04

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Phenotypic Discovery of an Antivirulence Agent against Vibrio vulnificus via Modulation of Quorum-Sensing Regulator SmcR

ACS infectious diseases, 2020-11, Vol.6 (11), p.3076-3082

2020

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Label-free target identification using in-gel fluorescence difference via thermal stability shift

Spatial snapshots of amyloid precursor protein intramembrane processing via early endosome proteomics

Recent advances in identifying protein targets in drug discovery

Label-free target identification reveals oxidative DNA damage as the mechanism of a selective cytotoxic agent

Label-free target identification in drug discovery via phenotypic screening

Label-free target identification reveals oxidative DNA damage as the mechanism of a selective cytotoxic agentElectronic supplementary information (ESI) available. See DOI: 10.1039/c8sc05465g

Label-free target identification reveals oxidative DNA damage as the mechanism of a selective cytotoxic agent† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc05465g

Discovery of a Small-Molecule Inhibitor of Protein–MicroRNA Interaction Using Binding Assay with a Site-Specifically Labeled Lin28

Systematic analysis of nonprogrammed frameshift suppression in E. coli via translational tiling proteomics

Phenotype-based screening rediscovered benzopyran-embedded microtubule inhibitors as anti-neuroinflammatory agents by modulating the tubulin-p65 interaction

Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cells

Phenotype-based discovery of a HeLa-specific cytotoxic molecule that downregulates HPV-mediated signaling pathways via oxidative damage

Phenotype-based discovery of a HeLa-specific cytotoxic molecule that downregulates HPV-mediated signaling pathways oxidative damage

Label-free target identification using in-gel fluorescence difference via thermal stability shiftElectronic supplementary information (ESI) available: Experimental details, NMR spectra, and other materials. See DOI: 10.1039/c6sc03238a

Label-free target identification using in-gel fluorescence difference via thermal stability shift† †Electronic supplementary information (ESI) available: Experimental details, NMR spectra, and other materials. See DOI: 10.1039/c6sc03238a Click here for additional data file

Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cellsElectronic supplementary information (ESI) available: Synthetic procedures, spectroscopic data of all new compounds, and procedures for biological experiment. See DOI: 10.1039/c6cc01426g

Phenotypic Discovery of an Antivirulence Agent against Vibrio vulnificus via Modulation of Quorum-Sensing Regulator SmcR

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