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Novel and flexible parameter estimation methods for data-consistent inversion in mechanistic modelling

Royal Society open science, 2023-11, Vol.10 (11), p.230668-230668

2023

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Model order reduction for left ventricular mechanics via congruency training

PloS one, 2020-01, Vol.15 (1), p.e0219876-e0219876

2020

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Novel Two-Step Classifier for Torsades de Pointes Risk Stratification from Direct Features

Frontiers in pharmacology, 2017-11, Vol.8, p.816-816

2017

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Global Sensitivity Analysis of Ventricular Myocyte Model-Derived Metrics for Proarrhythmic Risk Assessment

Frontiers in pharmacology, 2019-10, Vol.10, p.1054

2019

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Generative adversarial networks for construction of virtual populations of mechanistic models: simulations to study Omecamtiv Mecarbil action

Journal of pharmacokinetics and pharmacodynamics, 2022-02, Vol.49 (1), p.51-64

2022

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Neuronal population models reveal specific linear conductance controllers sufficient to rescue preclinical disease phenotypes

iScience, 2021-11, Vol.24 (11), p.103279-103279, Article 103279

2021

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Two heads are better than one: current landscape of integrating QSP and machine learning

Journal of pharmacokinetics and pharmacodynamics, 2022-02, Vol.49 (1), p.5-18

2022

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Model versus scientist: Cardiac toxicity predictions—safety pharmacologists correlate with the CiPA model

Journal of pharmacological and toxicological methods, 2021-09, Vol.111, p.107049, Article 107049

2021

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Effect of Spatial Heterogeneity and Colocalization of eNOS and Capacitative Calcium Entry Channels on Shear Stress-Induced NO Production by Endothelial Cells: A Modeling Approach

Cellular and molecular bioengineering, 2018-04, Vol.11 (2), p.143-155

2018

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Can endothelial hemoglobin-a regulate nitric oxide vasodilatory signaling?

American journal of physiology. Heart and circulatory physiology, 2017-04, Vol.312 (4), p.H854-H854

2017

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Can endothelial hemoglobin-α regulate nitric oxide vasodilatory signaling?

American journal of physiology. Heart and circulatory physiology, 2017-04, Vol.312 (4), p.H854-H866

2017

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Modeling Ca2+ signaling in the microcirculation: intercellular communication and vasoreactivity

Critical reviews in biomedical engineering, 2011, Vol.39 (5), p.435-460

2011

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Two heads are better than one: current landscape of integrating QSP and machine learning: An ISoP QSP SIG white paper by the working group on the integration of quantitative systems pharmacology and machine learning

Journal of pharmacokinetics and pharmacodynamics, 2022-02, Vol.49 (1), p.5-18

2022

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Stochastic Model of Endothelial TRPV4 Calcium Sparklets: Effect of Bursting and Cooperativity on EDH

Biophysical journal, 2015-03, Vol.108 (6), p.1566-1576

2015

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Multiscale computational models of microvascular reactivity from ion channels to intercellular signaling

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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Role of localized calcium events in regulation of vascular tone: A theoretical investigation

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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Role of electrical current and diffusion of second messengers in Ca2+ synchronization during vasomotion in microcirculation: Theoretical models

The FASEB journal, 2011-04, Vol.25, p.816.14-816.14

2011

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Multiple Factors Influence Calcium Synchronization in Arterial Vasomotion

Biophysical journal, 2012-01, Vol.102 (2), p.211-220

2012

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Mathematical model for shear stress dependent NO and adenine nucleotide production from endothelial cells

Nitric oxide, 2016-01, Vol.52, p.1-15

2016

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Theoretical investigation of intra- and inter-cellular spatiotemporal calcium patterns in microcirculation

Parikh, Jaimit

2015

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Comparing Model Simulation and Experimental Results to Study the Dependence on Shear Stress of NO, ATP and ADP Production from Endothelial Cells

XIV Mediterranean Conference on Medical and Biological Engineering and Computing 2016, 2016, Vol.57, p.524-524

2016

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Multi-scale modeling of microvascular reactivity

2014 IEEE 4th International Conference on Computational Advances in Bio and Medical Sciences (ICCABS), 2014, p.1-2

2014

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Neuronal Population Models Reveal Specific Linear Conductance Controllers Sufficient to Rescue Preclinical Disease Phenotypes

SSRN Electronic Journal

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Novel and flexible parameter estimation methods for data-consistent inversion in mechanistic modelling

Model order reduction for left ventricular mechanics via congruency training

Novel Two-Step Classifier for Torsades de Pointes Risk Stratification from Direct Features

Global Sensitivity Analysis of Ventricular Myocyte Model-Derived Metrics for Proarrhythmic Risk Assessment

Generative adversarial networks for construction of virtual populations of mechanistic models: simulations to study Omecamtiv Mecarbil action

Neuronal population models reveal specific linear conductance controllers sufficient to rescue preclinical disease phenotypes

Two heads are better than one: current landscape of integrating QSP and machine learning

Model versus scientist: Cardiac toxicity predictions—safety pharmacologists correlate with the CiPA model

Effect of Spatial Heterogeneity and Colocalization of eNOS and Capacitative Calcium Entry Channels on Shear Stress-Induced NO Production by Endothelial Cells: A Modeling Approach

Can endothelial hemoglobin-a regulate nitric oxide vasodilatory signaling?

Can endothelial hemoglobin-α regulate nitric oxide vasodilatory signaling?

Modeling Ca2+ signaling in the microcirculation: intercellular communication and vasoreactivity

Two heads are better than one: current landscape of integrating QSP and machine learning: An ISoP QSP SIG white paper by the working group on the integration of quantitative systems pharmacology and machine learning

Stochastic Model of Endothelial TRPV4 Calcium Sparklets: Effect of Bursting and Cooperativity on EDH

Multiscale computational models of microvascular reactivity from ion channels to intercellular signaling

Role of localized calcium events in regulation of vascular tone: A theoretical investigation

Role of electrical current and diffusion of second messengers in Ca2+ synchronization during vasomotion in microcirculation: Theoretical models

Multiple Factors Influence Calcium Synchronization in Arterial Vasomotion

Mathematical model for shear stress dependent NO and adenine nucleotide production from endothelial cells

Theoretical investigation of intra- and inter-cellular spatiotemporal calcium patterns in microcirculation

Comparing Model Simulation and Experimental Results to Study the Dependence on Shear Stress of NO, ATP and ADP Production from Endothelial Cells

Multi-scale modeling of microvascular reactivity

Neuronal Population Models Reveal Specific Linear Conductance Controllers Sufficient to Rescue Preclinical Disease Phenotypes

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