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APP Receptor? To Be or Not To Be

Trends in pharmacological sciences (Regular ed.), 2016-05, Vol.37 (5), p.390-411

2016

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A Function for EHD Family Proteins in Unidirectional Retrograde Dendritic Transport of BACE1 and Alzheimer’s Disease Aβ Production

Cell reports (Cambridge), 2013-12, Vol.5 (6), p.1552-1563

2013

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Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice

Molecular neurodegeneration, 2011-12, Vol.6 (1), p.87-87, Article 87

2011

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Modeling Presenilin-Dependent Familial Alzheimer's Disease : Emphasis on Presenilin Substrate-Mediated Signaling and Synaptic Function

International journal of alzheimer's disease, 2010, Vol.2010 (2010), p.1-11

2010

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Steady-state increase of cAMP-response element binding protein, Rac, and PAK signaling in presenilin-deficient neurons

Journal of neurochemistry, 2008-03, Vol.104 (6), p.1637-1648

2008

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Novel GαS-protein signaling associated with membrane-tethered amyloid precursor protein intracellular domain

The Journal of neuroscience, 2012-02, Vol.32 (5), p.1714-1729

2012

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Loss of presenilin function is associated with a selective gain of APP function

eLife, 2016-05, Vol.5

2016

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Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer’s disease

Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (45), p.E9665-E9674

2017

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APP-Mediated Signaling Prevents Memory Decline in Alzheimer’s Disease Mouse Model

Cell reports (Cambridge), 2019-04, Vol.27 (5), p.1345-1355.e6

2019

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Mutation Analysis of the Presenilin 1 N-terminal Domain Reveals a Broad Spectrum of γ-Secretase Activity toward Amyloid Precursor Protein and Other Substrates

The Journal of biological chemistry, 2010-12, Vol.285 (49), p.38042-38052

2010

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Spatial segregation of gamma-secretase and substrates in distinct membrane domains

The Journal of biological chemistry, 2005-07, Vol.280 (27), p.25892-25900

2005

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Identification of the role of presenilins beyond Alzheimer’s disease

Pharmacological research, 2004-10, Vol.50 (4), p.411-418

2004

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D-Serine Is an Endogenous Ligand for the Glycine Site of the N-Methyl-D-Aspartate Receptor

Proceedings of the National Academy of Sciences - PNAS, 2000-04, Vol.97 (9), p.4926-4931

2000

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Reduced Alzheimer's Disease β-Amyloid Deposition in Transgenic Mice Expressing S -Palmitoylation-Deficient APH1aL and Nicastrin

The Journal of neuroscience, 2010-12, Vol.30 (48), p.16160-16169

2010

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Evidence That CD147 Modulation of β-Amyloid (Aβ) Levels Is Mediated by Extracellular Degradation of Secreted Aβ

The Journal of biological chemistry, 2008-07, Vol.283 (28), p.19489-19498

2008

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Localization and regional distribution of p23/TMP21 in the brain

Neurobiology of disease, 2008-10, Vol.32 (1), p.37-49

2008

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Presenilin Attenuates Receptor-Mediated Signaling and Synaptic Function

The Journal of neuroscience, 2005-02, Vol.25 (6), p.1540-1549

2005

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Stringently regulated p23 expression is critical for coordinated movement in mice: implications for Alzheimer’s disease

Molecular neurodegeneration, 2012-02, Vol.7 (Suppl 1), p.L2-L2

2012

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Regulation of dynamic BACE1 trafficking in neurons

Molecular neurodegeneration, 2013-09, Vol.8 (S1), p.O8-O8, Article O8

2013

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Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta

The Journal of biological chemistry, 2008-07, Vol.283 (28), p.19489-19498

2008

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A Novel Function for EHD Family Proteins in Unidirectional Retrograde Dendritic Transport of BACE1 and Alzheimer's disease Aβ production

Cell reports (Cambridge), 2013-12, Vol.5 (6), p.1552-1563

2013

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P4-304 Abrogation of presenilin function increases cAMP-dependent synaptic transmission: influence of presenilin-dependent proteolysis of DCC receptor

Neurobiology of aging, 2004-07, Vol.25, p.S561-S562

2004

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Spatial Segregation of γ-Secretase and Substrates in DistinctMembraneDomains

The Journal of biological chemistry, 2005-07, Vol.280 (27), p.25892-25900

2005

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Reduced Alzheimer's disease ß-amyloid deposition in transgenic mice expressing S-palmitoylation-deficient APH1aL and nicastrin

The Journal of neuroscience, 2010-12, Vol.30 (48), p.16160-16169

2010

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Inositol hexakisphosphate-mediated regulation of glutamate receptors in rat brain sections

Hippocampus, 2001, Vol.11 (6), p.673-682

2001

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APP Receptor? To Be or Not To Be

A Function for EHD Family Proteins in Unidirectional Retrograde Dendritic Transport of BACE1 and Alzheimer’s Disease Aβ Production

Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice

Modeling Presenilin-Dependent Familial Alzheimer's Disease : Emphasis on Presenilin Substrate-Mediated Signaling and Synaptic Function

Steady-state increase of cAMP-response element binding protein, Rac, and PAK signaling in presenilin-deficient neurons

Novel GαS-protein signaling associated with membrane-tethered amyloid precursor protein intracellular domain

Loss of presenilin function is associated with a selective gain of APP function

Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer’s disease

APP-Mediated Signaling Prevents Memory Decline in Alzheimer’s Disease Mouse Model

Mutation Analysis of the Presenilin 1 N-terminal Domain Reveals a Broad Spectrum of γ-Secretase Activity toward Amyloid Precursor Protein and Other Substrates

Spatial segregation of gamma-secretase and substrates in distinct membrane domains

Identification of the role of presenilins beyond Alzheimer’s disease

D-Serine Is an Endogenous Ligand for the Glycine Site of the N-Methyl-D-Aspartate Receptor

Reduced Alzheimer's Disease β-Amyloid Deposition in Transgenic Mice Expressing S -Palmitoylation-Deficient APH1aL and Nicastrin

Evidence That CD147 Modulation of β-Amyloid (Aβ) Levels Is Mediated by Extracellular Degradation of Secreted Aβ

Localization and regional distribution of p23/TMP21 in the brain

Presenilin Attenuates Receptor-Mediated Signaling and Synaptic Function

Stringently regulated p23 expression is critical for coordinated movement in mice: implications for Alzheimer’s disease

Regulation of dynamic BACE1 trafficking in neurons

Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta

A Novel Function for EHD Family Proteins in Unidirectional Retrograde Dendritic Transport of BACE1 and Alzheimer's disease Aβ production

P4-304 Abrogation of presenilin function increases cAMP-dependent synaptic transmission: influence of presenilin-dependent proteolysis of DCC receptor

Spatial Segregation of γ-Secretase and Substrates in DistinctMembraneDomains

Reduced Alzheimer's disease ß-amyloid deposition in transgenic mice expressing S-palmitoylation-deficient APH1aL and nicastrin

Inositol hexakisphosphate-mediated regulation of glutamate receptors in rat brain sections

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