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From Bradykinin B2 Receptor Antagonists to Orally Active and Selective Bradykinin B1 Receptor Antagonists

Journal of medicinal chemistry, 2012-03, Vol.55 (6), p.2574-2584

2012

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Cloning and characterization of guinea pig interleukin-8 receptor

Biochemical pharmacology, 2003-10, Vol.66 (7), p.1171-1180

2003

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Characterization of the molecular interactions of interleukin-8 (CXCL8), growth related oncogen α (CXCL1) and a non-peptide antagonist (SB 225002) with the human CXCR2

Biochemical pharmacology, 2003-03, Vol.65 (5), p.813-821

2003

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Identification of a Key Region of Kinin B1 Receptor for High Affinity Binding of Peptide Antagonists

The Journal of biological chemistry, 2000-03, Vol.275 (9), p.6107-6113

2000

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LF 16.0335, a novel potent and selective nonpeptide antagonist of the human bradykinin B2 receptor

British journal of pharmacology, 1998-09, Vol.125 (2), p.365-372

1998

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Design and Synthesis of Potent Bradykinin Agonists Containing a Benzothiazepine Moiety

Journal of medicinal chemistry, 1999-10, Vol.42 (20), p.4185-4192

1999

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In vitro and in vivo effects of the new nonpeptide bradykinin B2 receptor antagonist, LF 16-0335C, on guinea-pig and rat kinin receptors

Fundamental & clinical pharmacology, 1999-01, Vol.13 (1), p.75-83

1999

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Angiotensin II-induced proliferation of aortic myocytes in spontaneously hypertensive rats

Journal of hypertension, 1990-06, Vol.8 (6), p.565-572

1990

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A Rational Approach to the Design and Synthesis of a New Bradykinin B1 Receptor Antagonist

Journal of medicinal chemistry, 2000-06, Vol.43 (12), p.2387-2394

2000

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Synthesis and Characterization of Bradykinin B2 Receptor Agonists Containing Constrained Dipeptide Mimics

Journal of medicinal chemistry, 1999-10, Vol.42 (20), p.4193-4201

1999

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Human substance P receptor (NK-1): organization of the gene, chromosome localization and functional expression of cDNA clones

Biochemistry (Easton), 1991-11, Vol.30 (44), p.10640-10646

1991

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Synthesis and Biological Evaluation of Bradykinin B1/B2 and Selective B1 Receptor Antagonists

Journal of medicinal chemistry, 2000-06, Vol.43 (12), p.2382-2386

2000

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Control of Conformational Equilibria in the Human B2 Bradykinin Receptor

The Journal of biological chemistry, 2001-11, Vol.276 (44), p.41100-41111

2001

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LF 16.0335, a novel potent and selective nonpeptide antagonist of the human bradykinin B 2 receptor

British journal of pharmacology, 2009-02, Vol.125 (2), p.365-372

2009

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Characterisation of bradykinin receptors from juvenile pig coronary artery

European journal of pharmacology, 1996-02, Vol.297 (1), p.53-60

1996

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Enhanced Proliferating Activity of Cultured Smooth Muscle Cells From SHR

American journal of hypertension, 1989-02, Vol.2 (2-Pt-1), p.108-110

1989

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Enhanced response to growth factors and to angiotensin II of spontaneously hypertensive rat skin fibroblasts in culture

Journal of hypertension, 1991-01, Vol.9 (1), p.23-28

1991

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Control of conformational equilibria in the human B2 bradykinin receptor. Modeling of nonpeptidic ligand action and comparison to the rhodopsin structure

The Journal of biological chemistry, 2001-11, Vol.276 (44), p.41100

2001

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Role of nuclear proto-oncogenes in the proliferation of aortic smooth muscle cells in spontaneously hypertensive rats

Journal of hypertension, 1989-12, Vol.7 Suppl 6 (6), p.S114-115

1989

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Hyperactivation of Phospholipase C Does not Support the Enhanced Proliferation of Aortic Smooth Muscle Cells From Spontaneously Hypertensive Rats

American journal of hypertension, 1991-08, Vol.4 (8), p.651-660

1991

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Growth rate and phospholipase C activity in cardiac and aortic spontaneously hypertensive rat cells

Journal of hypertension, 1988-12, Vol.6 (4), p.S369-371

1988

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Constitutive activation of the human bradykinin B2 receptor induced by mutations in transmembrane helices III and VI

Molecular pharmacology, 1999-01, Vol.55 (1), p.92

1999

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Constitutive Activation of the Human Bradykinin B 2 Receptor Induced by Mutations in Transmembrane Helices III and VI

Molecular pharmacology, 1999-01, Vol.55 (1), p.92-101

1999

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Role of acidic amino acids in the allosteric modulation by gallamine of antagonist binding at the m2 muscarinic acetylcholine receptor

Molecular pharmacology, 1994-05, Vol.45 (5), p.983-990

1994

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A Rational Approach to the Design and Synthesis of a New Bradykinin B 1 Receptor Antagonist

Journal of medicinal chemistry, 2000-06, Vol.43 (12), p.2387-2394

2000

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From Bradykinin B2 Receptor Antagonists to Orally Active and Selective Bradykinin B1 Receptor Antagonists

Cloning and characterization of guinea pig interleukin-8 receptor

Characterization of the molecular interactions of interleukin-8 (CXCL8), growth related oncogen α (CXCL1) and a non-peptide antagonist (SB 225002) with the human CXCR2

Identification of a Key Region of Kinin B1 Receptor for High Affinity Binding of Peptide Antagonists

LF 16.0335, a novel potent and selective nonpeptide antagonist of the human bradykinin B2 receptor

Design and Synthesis of Potent Bradykinin Agonists Containing a Benzothiazepine Moiety

In vitro and in vivo effects of the new nonpeptide bradykinin B2 receptor antagonist, LF 16-0335C, on guinea-pig and rat kinin receptors

Angiotensin II-induced proliferation of aortic myocytes in spontaneously hypertensive rats

A Rational Approach to the Design and Synthesis of a New Bradykinin B1 Receptor Antagonist

Synthesis and Characterization of Bradykinin B2 Receptor Agonists Containing Constrained Dipeptide Mimics

Human substance P receptor (NK-1): organization of the gene, chromosome localization and functional expression of cDNA clones

Synthesis and Biological Evaluation of Bradykinin B1/B2 and Selective B1 Receptor Antagonists

Control of Conformational Equilibria in the Human B2 Bradykinin Receptor

LF 16.0335, a novel potent and selective nonpeptide antagonist of the human bradykinin B 2 receptor

Characterisation of bradykinin receptors from juvenile pig coronary artery

Enhanced Proliferating Activity of Cultured Smooth Muscle Cells From SHR

Enhanced response to growth factors and to angiotensin II of spontaneously hypertensive rat skin fibroblasts in culture

Control of conformational equilibria in the human B2 bradykinin receptor. Modeling of nonpeptidic ligand action and comparison to the rhodopsin structure

Role of nuclear proto-oncogenes in the proliferation of aortic smooth muscle cells in spontaneously hypertensive rats

Hyperactivation of Phospholipase C Does not Support the Enhanced Proliferation of Aortic Smooth Muscle Cells From Spontaneously Hypertensive Rats

Growth rate and phospholipase C activity in cardiac and aortic spontaneously hypertensive rat cells

Constitutive activation of the human bradykinin B2 receptor induced by mutations in transmembrane helices III and VI

Constitutive Activation of the Human Bradykinin B 2 Receptor Induced by Mutations in Transmembrane Helices III and VI

Role of acidic amino acids in the allosteric modulation by gallamine of antagonist binding at the m2 muscarinic acetylcholine receptor

A Rational Approach to the Design and Synthesis of a New Bradykinin B 1 Receptor Antagonist

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