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Implications of Promiscuous Pim-1 Kinase Fragment Inhibitor Hydrophobic Interactions for Fragment-Based Drug Design

Journal of medicinal chemistry, 2012-03, Vol.55 (6), p.2641-2648

2012

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GT160-246, a toxin binding polymer for treatment of Clostridium difficile colitis

Antimicrobial agents and chemotherapy, 2001-08, Vol.45 (8), p.2340-2347

2001

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Structure-Based Design of Selective Inhibitors of Dihydrofolate Reductase: Synthesis and Antiparasitic Activity of 2,4-Diaminopteridine Analogues with a Bridged Diarylamine Side Chain

Journal of medicinal chemistry, 1999-11, Vol.42 (23), p.4853-4860

1999

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Synthesis and Antiparasitic and Antitumor Activity of 2,4-Diamino-6-(arylmethyl)-5,6,7,8-tetrahydroquinazoline Analogues of Piritrexim

Journal of medicinal chemistry, 1999-03, Vol.42 (6), p.1007-1017

1999

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2,4-Diaminothieno[2,3-d]pyrimidine Lipophilic Antifolates as Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

Journal of medicinal chemistry, 1997-10, Vol.40 (22), p.3694-3699

1997

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2,4-Diaminothieno[2,3-d]pyrimidine Lipophilic Antifolates as Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

Journal of medicinal chemistry, 2003-07, Vol.46 (15), p.3424-3424

2003

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2,4-Diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidine Analogues of Trimethoprim as Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

Journal of medicinal chemistry, 1998-03, Vol.41 (6), p.913-918

1998

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The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (10), p.3050-3056

2011

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2,4-Diaminothieno[2,3-d]pyrimidine Lipophilic Antifolates as Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

Journal of medicinal chemistry, 2002-04, Vol.45 (9), p.1957-1957

2002

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Abstract 2790: Discovery of novel Pim-1 inhibitors

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.2790-2790

2011

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Identification of N2-(1-Carboxyethyl)guanine (CEG) as a Guanine Advanced Glycosylation End Product

Biochemistry (Easton), 1995-01, Vol.34 (2), p.648-655

1995

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GT160-246, a Toxin Binding Polymer for Treatment ofClostridium difficile Colitis

Antimicrobial Agents and Chemotherapy, 2001-08, Vol.45 (8), p.2340-2347

2001

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2,4-Diamino-6,7-dihydro-5 H -cyclopenta[ d ]pyrimidine Analogues of Trimethoprim as Inhibitors of Pneumocystis c arinii and Toxoplasma g ondii Dihydrofolate Reductase

Journal of medicinal chemistry, 2002-04, Vol.45 (9), p.1957-1957

2002

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2,4-Diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidine Analogues of Trimethoprim as Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

Journal of medicinal chemistry, 2002-04, Vol.45 (9), p.1957-1957

2002

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Synthesis and Antiparasitic and Antitumor Activity of 2,4-Diamino-6-(arylmethyl)-5,6,7,8-tetrahydroquinazoline Analogues of Piritrexim

Journal of medicinal chemistry, 2002-04, Vol.45 (9), p.1957-1958

2002

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Ion-Selective Hydrazone-Azine Tautomerism of a 14-Membered Macrocylic Ligand

Angewandte Chemie (International ed.), 1992-06, Vol.31 (6), p.749-751

1992

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2,4-Diamino-6,7-dihydro-5 H -cyclopenta[ d ]pyrimidine Analogues of Trimethoprim as Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

Journal of medicinal chemistry, 1998-03, Vol.41 (6), p.913-918

1998

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One-step synthesis of novel 2,4-diaminopyrimidine antifolates from bridged alicyclic ketones and cyanoguanidine

Journal of heterocyclic chemistry, 1999-05, Vol.36 (3), p.723-728

1999

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Identification of N 2-(1-carboxymethyl)guanine (CMG) as a guanine advanced glycation end product

Bioorganic & medicinal chemistry letters, 1998-08, Vol.8 (16), p.2109-2110

1998

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Synthesis of new torands and new uses for old torands

Pure and applied chemistry, 1993-01, Vol.65 (3), p.361-366

1993

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Identification of N2-(1-carboxymethyl)guanine (CMB) as a guanine advanced glycation end product

Bioorganic & medicinal chemistry letters, 1998-08, Vol.8 (16), p.2109-2110

1998

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2,4-Diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidine Analogues of Trimethoprim as Inhibitors of Pneumocystis c arinii and Toxoplasma g ondii Dihydrofolate Reductase

Journal of medicinal chemistry, 2002-04, Vol.45 (9), p.1957-1957

2002

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The synthesis and complexation of porphyrin analogs and pyrrole-containing receptors

Papoulis, Andrew

1992

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ProQuest

Ionenselektive Hydrazon-Azin-Tautomerisierung eines 14gliedrigen makrocyclischen Liganden

Angewandte Chemie, 1992-06, Vol.104 (6), p.792-794

1992

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Ionenselektive Hydrazon‐Azin‐Tautomerisierung eines 14gliedrigen makrocyclischen Liganden

Angewandte Chemie, 1992-06, Vol.104 (6), p.792-794

1992

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Implications of Promiscuous Pim-1 Kinase Fragment Inhibitor Hydrophobic Interactions for Fragment-Based Drug Design

GT160-246, a toxin binding polymer for treatment of Clostridium difficile colitis

Structure-Based Design of Selective Inhibitors of Dihydrofolate Reductase: Synthesis and Antiparasitic Activity of 2,4-Diaminopteridine Analogues with a Bridged Diarylamine Side Chain

Synthesis and Antiparasitic and Antitumor Activity of 2,4-Diamino-6-(arylmethyl)-5,6,7,8-tetrahydroquinazoline Analogues of Piritrexim

2,4-Diaminothieno[2,3-d]pyrimidine Lipophilic Antifolates as Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

2,4-Diaminothieno[2,3-d]pyrimidine Lipophilic Antifolates as Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

2,4-Diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidine Analogues of Trimethoprim as Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors

2,4-Diaminothieno[2,3-d]pyrimidine Lipophilic Antifolates as Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

Abstract 2790: Discovery of novel Pim-1 inhibitors

Identification of N2-(1-Carboxyethyl)guanine (CEG) as a Guanine Advanced Glycosylation End Product

GT160-246, a Toxin Binding Polymer for Treatment ofClostridium difficile Colitis

2,4-Diamino-6,7-dihydro-5 H -cyclopenta[ d ]pyrimidine Analogues of Trimethoprim as Inhibitors of Pneumocystis c arinii and Toxoplasma g ondii Dihydrofolate Reductase

2,4-Diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidine Analogues of Trimethoprim as Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

Synthesis and Antiparasitic and Antitumor Activity of 2,4-Diamino-6-(arylmethyl)-5,6,7,8-tetrahydroquinazoline Analogues of Piritrexim

Ion-Selective Hydrazone-Azine Tautomerism of a 14-Membered Macrocylic Ligand

2,4-Diamino-6,7-dihydro-5 H -cyclopenta[ d ]pyrimidine Analogues of Trimethoprim as Inhibitors of Pneumocystis carinii and Toxoplasma gondii Dihydrofolate Reductase

One-step synthesis of novel 2,4-diaminopyrimidine antifolates from bridged alicyclic ketones and cyanoguanidine

Identification of N 2-(1-carboxymethyl)guanine (CMG) as a guanine advanced glycation end product

Synthesis of new torands and new uses for old torands

Identification of N2-(1-carboxymethyl)guanine (CMB) as a guanine advanced glycation end product

2,4-Diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidine Analogues of Trimethoprim as Inhibitors of Pneumocystis c arinii and Toxoplasma g ondii Dihydrofolate Reductase

The synthesis and complexation of porphyrin analogs and pyrrole-containing receptors

Ionenselektive Hydrazon-Azin-Tautomerisierung eines 14gliedrigen makrocyclischen Liganden

Ionenselektive Hydrazon‐Azin‐Tautomerisierung eines 14gliedrigen makrocyclischen Liganden

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