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12 BIOLOGY OF MDS DISEASE PROGRESSION

Leukemia research, 2015-04, Vol.39, p.S4-S4

Papaemmanuil, E

2015

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Hemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts

Leukemia, 2017-03, Vol.31 (3), p.720-727

2017

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Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

Leukemia, 2015-05, Vol.29 (5), p.1092-1103

2015

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Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers

Nature communications, 2022-05, Vol.13 (1), p.2485-2485, Article 2485

2022

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Minimal morphological criteria for defining bone marrow dysplasia: a basis for clinical implementation of WHO classification of myelodysplastic syndromes

Leukemia, 2015-01, Vol.29 (1), p.66-75

2015

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RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features

Leukemia, 2016-11, Vol.30 (11), p.2160-2168

2016

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The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia

Oncogene, 2016-01, Vol.35 (3), p.279-289

2016

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The transporter ABCB7 is a mediator of the phenotype of acquired refractory anemia with ring sideroblasts

Leukemia, 2013-04, Vol.27 (4), p.889-896

2013

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EARLY TRANSFUSION PATTERNS PREDICT OUTCOMES INDEPENDENTLY OF IPSS-M SCORE IN MYELODYSPLASTIC SYNDROMES

LEUKEMIA RESEARCH, 2023-05, Vol.128, p.107119, Article 107119

2023

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RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features

Leukemia, 2016-11, Vol.30 (11), p.2282

2016

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POST-AZACITIDINE CLONE SIZE PREDICTS LONG-TERM OUTCOME OF PATIENTS WITH MYELODYSPLASTIC SYNDROMES AND RELATED MYELOID NEOPLASMS

LEUKEMIA RESEARCH, 2023-05, Vol.128, p.107124, Article 107124

2023

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Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups

Leukemia, 2017-12

2017

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Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

Leukemia, 2015-08, Vol.29 (8), p.1798-1798

2015

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National study of colorectal cancer genetics

British journal of cancer, 2007-11, Vol.97 (9), p.1305-1309

2007

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Classification and Personalized Prognosis in Myeloproliferative Neoplasms

The New England journal of medicine, 2018-10, Vol.379 (15), p.1416-1430

2018

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Identification of Aberrant Splicing Events in Myelodysplastic Syndrome Patients with Splicing Factor Gene Mutations

Leukemia research, 2017-04, Vol.55, p.S9-S9

2017

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74 CHARACTERIZATION OF THE HEMATOPOIETIC STEM AND PROGENITOR CELL HIERARCHY IN MYELODYSPLASTIC SYNDROMES PATIENTS WITH MONOSOMY 7 AS THE SOLE CYTOGENETIC ABNORMALITY

Leukemia research, 2015-04, Vol.39, p.S36-S36

2015

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407: Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia

European journal of cancer (1990), 2014-07, Vol.50, p.S97-S97

2014

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SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts

Blood, 2015-07, Vol.126 (2), p.233-241

2015

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Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes

Nature communications, 2015-01, Vol.6 (1), p.5901-5901, Article 5901

2015

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SF3B1-initiating mutations in MDS-RSs target lymphomyeloid hematopoietic stem cells

Blood, 2017-08, Vol.130 (7), p.881-890

2017

Volltextzugriff (PDF)

72 PERSONALIZED TREATMENT APPROACH FOR GFI136N HETEROZYGOUS OR HOMOZYGOUS MDS PATIENTS

Leukemia research, 2015-04, Vol.39, p.S35-S35

2015

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12 BIOLOGY OF MDS DISEASE PROGRESSION

Hemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts

Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers

Minimal morphological criteria for defining bone marrow dysplasia: a basis for clinical implementation of WHO classification of myelodysplastic syndromes

RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia

The transporter ABCB7 is a mediator of the phenotype of acquired refractory anemia with ring sideroblasts

EARLY TRANSFUSION PATTERNS PREDICT OUTCOMES INDEPENDENTLY OF IPSS-M SCORE IN MYELODYSPLASTIC SYNDROMES

RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features

POST-AZACITIDINE CLONE SIZE PREDICTS LONG-TERM OUTCOME OF PATIENTS WITH MYELODYSPLASTIC SYNDROMES AND RELATED MYELOID NEOPLASMS

Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups

Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

National study of colorectal cancer genetics

Classification and Personalized Prognosis in Myeloproliferative Neoplasms

Identification of Aberrant Splicing Events in Myelodysplastic Syndrome Patients with Splicing Factor Gene Mutations

74 CHARACTERIZATION OF THE HEMATOPOIETIC STEM AND PROGENITOR CELL HIERARCHY IN MYELODYSPLASTIC SYNDROMES PATIENTS WITH MONOSOMY 7 AS THE SOLE CYTOGENETIC ABNORMALITY

407: Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia

SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts

Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations

Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes

SF3B1-initiating mutations in MDS-RSs target lymphomyeloid hematopoietic stem cells

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome

Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms

72 PERSONALIZED TREATMENT APPROACH FOR GFI136N HETEROZYGOUS OR HOMOZYGOUS MDS PATIENTS

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