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Analysis of CD74 Occurrence in Oncogenic Fusion Proteins

International journal of molecular sciences, 2023-11, Vol.24 (21), p.15981

2023

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Protocol for purification and enzymatic characterization of members of the human macrophage migration inhibitory factor superfamily

STAR protocols, 2023-09, Vol.4 (3), p.102375-102375, Article 102375

2023

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A novel enzymatic assay for the identification of 4-hydroxyphenylpyruvate dioxygenase modulators

STAR protocols, 2023-06, Vol.4 (2), p.102300-102300, Article 102300

2023

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Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1

Amino acids, 2014-09, Vol.46 (9), p.2155-2163

2014

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Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose

Molecular medicine (Cambridge, Mass.), 2024-03, Vol.30 (1), p.43-11, Article 43

2024

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A Cysteine Variant at an Allosteric Site Alters MIF Dynamics and Biological Function in Homo- and Heterotrimeric Assemblies

Frontiers in molecular biosciences, 2022-02, Vol.9, p.783669-783669

2022

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Structural Plasticity in the C‑Terminal Region of Macrophage Migration Inhibitory Factor‑2 Is Associated with an Induced Fit Mechanism for a Selective Inhibitor

Biochemistry (Easton), 2018-07, Vol.57 (26), p.3599-3605

2018

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Hands-On Methods to Educate High School Students about Cancer Research

Journal of chemical education, 2023-06, Vol.100 (6), p.2312-2319

2023

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Antitumour agents as inhibitors of tryptophan 2,3-dioxygenase

Biochemical and biophysical research communications, 2014-01, Vol.443 (1), p.28-31

2014

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2,5-Pyridinedicarboxylic acid is a bioactive and highly selective inhibitor of D-dopachrome tautomerase

Structure (London), 2023-03, Vol.31 (3), p.355-367.e4

2023

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The N-terminus of MIF controls the flexibility of specific β-sheet residues resulting in dynamic regulation of CD74 activation

Biophysical journal, 2022-02, Vol.121 (3), p.334a-334a

2022

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The N-terminus of MIF regulates the dynamic profile of residues involved in CD74 activation

Biophysical journal, 2021-09, Vol.120 (18), p.3893-3900

2021

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2,5-Pyridinedicarboxylic acid is a bioactive and highly selective inhibitor of D-dopachrome tautomerase

Structure (London), 2023-03, Vol.31 (3)

2023

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Structural analysis reveals key residues in D-Dopachrome tautomerase functionality

Biophysical journal, 2024-02, Vol.123 (3), p.54a-54a

2024

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Underrepresented Impurities in 4‑Hydroxyphenylpyruvate Affect the Catalytic Activity of Multiple Enzymes

Analytical chemistry (Washington), 2023-03, Vol.95 (11), p.4957-4965

2023

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Ligand-induced conformational changes enable intersubunit communications in D-dopachrome tautomerase

Biophysical journal, 2023-04, Vol.122 (7), p.1268-1276

2023

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Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel

Cell chemical biology, 2020-06, Vol.27 (6), p.740-750.e5

2020

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A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity

The Journal of biological chemistry, 2019-12, Vol.294 (49), p.18522-18531

2019

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MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model

The Journal of clinical investigation, 2021-12, Vol.131 (23)

2021

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A small-molecule allele-selective transcriptional inhibitor of the MIF immune susceptibility locus

The Journal of biological chemistry, 2024-07, Vol.300 (7), p.107443, Article 107443

2024

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The C‑terminal Region of D‑DT Regulates Molecular Recognition for Protein–Ligand Complexes

Journal of medicinal chemistry, 2024-05, Vol.67 (9), p.7359-7372

2024

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Nanosecond Dynamics Regulate the MIF‐Induced Activity of CD74

Angewandte Chemie (International ed.), 2018-06, Vol.57 (24), p.7116-7119

International ed. in English, 2018

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Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4

Scientific reports, 2018-03, Vol.8 (1), p.5171-17, Article 5171

2018

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Structural basis for decreased induction of class IB PI3‐kinases expression by MIF inhibitors

Journal of cellular and molecular medicine, 2017-01, Vol.21 (1), p.142-153

2017

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The N‐terminal length and side‐chain composition of CXCL13 affect crystallization, structure and functional activity

Acta crystallographica. Section D, Biological crystallography., 2020-10, Vol.76 (10), p.1033-1049

2020

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Analysis of CD74 Occurrence in Oncogenic Fusion Proteins

Protocol for purification and enzymatic characterization of members of the human macrophage migration inhibitory factor superfamily

A novel enzymatic assay for the identification of 4-hydroxyphenylpyruvate dioxygenase modulators

Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1

Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose

A Cysteine Variant at an Allosteric Site Alters MIF Dynamics and Biological Function in Homo- and Heterotrimeric Assemblies

Structural Plasticity in the C‑Terminal Region of Macrophage Migration Inhibitory Factor‑2 Is Associated with an Induced Fit Mechanism for a Selective Inhibitor

Hands-On Methods to Educate High School Students about Cancer Research

Antitumour agents as inhibitors of tryptophan 2,3-dioxygenase

2,5-Pyridinedicarboxylic acid is a bioactive and highly selective inhibitor of D-dopachrome tautomerase

The N-terminus of MIF controls the flexibility of specific β-sheet residues resulting in dynamic regulation of CD74 activation

The N-terminus of MIF regulates the dynamic profile of residues involved in CD74 activation

2,5-Pyridinedicarboxylic acid is a bioactive and highly selective inhibitor of D-dopachrome tautomerase

Structural analysis reveals key residues in D-Dopachrome tautomerase functionality

Underrepresented Impurities in 4‑Hydroxyphenylpyruvate Affect the Catalytic Activity of Multiple Enzymes

Ligand-induced conformational changes enable intersubunit communications in D-dopachrome tautomerase

Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel

A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity

MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model

A small-molecule allele-selective transcriptional inhibitor of the MIF immune susceptibility locus

The C‑terminal Region of D‑DT Regulates Molecular Recognition for Protein–Ligand Complexes

Nanosecond Dynamics Regulate the MIF‐Induced Activity of CD74

Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4

Structural basis for decreased induction of class IB PI3‐kinases expression by MIF inhibitors

The N‐terminal length and side‐chain composition of CXCL13 affect crystallization, structure and functional activity

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