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ACE2 X-Ray Structures Reveal a Large Hinge-bending Motion Important for Inhibitor Binding and Catalysis

Journal of molecular biology, 2004-04, Vol.279 (17), p.17996-18007

2004

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Energetic Characterization of the Basic Fibroblast Growth Factor-Heparin Interaction: Identification of the Heparin Binding Domain

Biochemistry (Easton), 1994-04, Vol.33 (13), p.3831-3840

1994

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Crystallographic and thermodynamic comparison of natural and synthetic ligands bound to streptavidin

Journal of the American Chemical Society, 1992-04, Vol.114 (9), p.3197-3200

1992

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In Vivo Tumor Targeting of a Recombinant Single-Chain Antigen-Binding Protein

JNCI : Journal of the National Cancer Institute, 1990-07, Vol.82 (14), p.1191-1197

1990

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Site-Directed Mutagenesis and the Role of the Oxyanion Hole in Subtilisin

Proceedings of the National Academy of Sciences - PNAS, 1986-06, Vol.83 (11), p.3743-3745

1986

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Structure-Based Design of Synthetic Azobenzene Ligands for Streptavidin

Journal of the American Chemical Society, 1994-04, Vol.116 (7), p.2717-2724

1994

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Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding

Biochemistry (Easton), 1989-09, Vol.28 (18), p.7205-7213

1989

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Crystal structure and ligand binding studies of a screened peptide complexed with streptavidin

Biochemistry (Easton), 1992-10, Vol.31 (39), p.9350-9354

1992

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Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor Dimerization

Biochemistry (Easton), 1994-08, Vol.33 (34), p.10229-10248

1994

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Identification and concerted function of two receptor binding surfaces on basic fibroblast growth factor required for mitogenesis

The Journal of biological chemistry, 1994-10, Vol.269 (43), p.26879-26884

1994

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Immunological and structural characterization of a high affinity anti-fluorescein single-chain antibody

The Journal of biological chemistry, 1990-10, Vol.265 (30), p.18615-18620

1990

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High-density miniaturized thermal shift assays as a general strategy for drug discovery

Journal of biomolecular screening, 2001-12, Vol.6 (6), p.429

2001

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Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.909-912

2005

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Conformational stability, folding, and ligand-binding affinity of single-chain Fv immunoglobulin fragments expressed in Escherichia coli

Biochemistry (Easton), 1991-10, Vol.30 (42), p.10117-10125

1991

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Affinity chromatographic purification of angiotensin converting enzyme

Biochemistry (Easton), 1984-02, Vol.23 (5), p.1037-1042

1984

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Protein engineering of subtilisin BPN': enhanced stabilization through the introduction of two cysteines to form a disulfide bond

Biochemistry (Easton), 1987-04, Vol.26 (8), p.2077-2082

1987

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The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: subtilisin as a test case

Biochemistry (Easton), 1988-11, Vol.27 (22), p.8311-8317

1988

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PH [hydrogen-ion concentration]-dependent migration of copper(II) to the vacant zinc-binding site of zinc-free bovine erythrocyte superoxide dismutase

Proceedings of the National Academy of Sciences - PNAS, 1979-09, Vol.76 (9), p.4245-4249

1979

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Crystallographic and thermodynamic comparison of structurally diverse molecules binding to streptavidin

Acta crystallographica. Section D, Biological crystallography., 1995-07, Vol.51 (4), p.590-596

1995

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Enzymes in organic synthesis: use of subtilisin and a highly stable mutant derived from multiple site-specific mutations

Journal of the American Chemical Society, 1990, Vol.112 (3), p.945-953

1990

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Nuclear magnetic resonance and chemical modification studies of bovine erythrocyte superoxide dismutase: evidence for zinc-promoted organization of the active site structure

Biochemistry (Easton), 1977-03, Vol.16 (6), p.1136-1141

1977

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Engineering Thermostability in Subtilisin BPN' by in Vitro Mutagenesis

Critical reviews in biotechnology, 1988, Vol.8 (3), p.217-224

1988

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A pH-dependent superoxide dismutase activity for zinc-free bovine erythrocuprein. Reexamination of the role of zinc in the holoprotein

Journal of inorganic biochemistry, 1982, Vol.17 (4), p.325-341

1982

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Spectroscopic studies of copper(II) bound at the native copper site or substituted at the native zinc site of bovine erythrocuprein (superoxide dismutase)

Journal of the American Chemical Society, 1982-11, Vol.104 (23), p.6310-6317

1982

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Conformational stability, folding, and ligand-binding affinity of single-chain Fv immunoglobulin fragments expressed in Escherichia coli

Biochemistry (Easton), 1991-01, Vol.30 (4), p.10117-10125

1991

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ACE2 X-Ray Structures Reveal a Large Hinge-bending Motion Important for Inhibitor Binding and Catalysis

Energetic Characterization of the Basic Fibroblast Growth Factor-Heparin Interaction: Identification of the Heparin Binding Domain

Crystallographic and thermodynamic comparison of natural and synthetic ligands bound to streptavidin

In Vivo Tumor Targeting of a Recombinant Single-Chain Antigen-Binding Protein

Site-Directed Mutagenesis and the Role of the Oxyanion Hole in Subtilisin

Structure-Based Design of Synthetic Azobenzene Ligands for Streptavidin

Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding

Crystal structure and ligand binding studies of a screened peptide complexed with streptavidin

Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor Dimerization

Identification and concerted function of two receptor binding surfaces on basic fibroblast growth factor required for mitogenesis

Immunological and structural characterization of a high affinity anti-fluorescein single-chain antibody

High-density miniaturized thermal shift assays as a general strategy for drug discovery

Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells

Conformational stability, folding, and ligand-binding affinity of single-chain Fv immunoglobulin fragments expressed in Escherichia coli

Affinity chromatographic purification of angiotensin converting enzyme

Protein engineering of subtilisin BPN': enhanced stabilization through the introduction of two cysteines to form a disulfide bond

The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: subtilisin as a test case

PH [hydrogen-ion concentration]-dependent migration of copper(II) to the vacant zinc-binding site of zinc-free bovine erythrocyte superoxide dismutase

Crystallographic and thermodynamic comparison of structurally diverse molecules binding to streptavidin

Enzymes in organic synthesis: use of subtilisin and a highly stable mutant derived from multiple site-specific mutations

Nuclear magnetic resonance and chemical modification studies of bovine erythrocyte superoxide dismutase: evidence for zinc-promoted organization of the active site structure

Engineering Thermostability in Subtilisin BPN' by in Vitro Mutagenesis

A pH-dependent superoxide dismutase activity for zinc-free bovine erythrocuprein. Reexamination of the role of zinc in the holoprotein

Spectroscopic studies of copper(II) bound at the native copper site or substituted at the native zinc site of bovine erythrocuprein (superoxide dismutase)

Conformational stability, folding, and ligand-binding affinity of single-chain Fv immunoglobulin fragments expressed in Escherichia coli

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