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Direct evidence of phosphorylated neuronal intermediate filament proteins in neurofibrillary tangles (NFTs): phosphoproteomics of Alzheimer's NFTs

The FASEB journal, 2011-11, Vol.25 (11), p.3896-3905

2011

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Overexpression of the Cdk5 inhibitory peptide in motor neurons rescue of amyotrophic lateral sclerosis phenotype in a mouse model

Human molecular genetics, 2019-10, Vol.28 (19), p.3175-3187

2019

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Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments

Experimental cell research, 2007-06, Vol.313 (10), p.2098-2109

2007

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Achaete-scute homologue-1 (ASH1) stimulates migration of lung cancer cells through Cdk5/p35 pathway

Molecular biology of the cell, 2012-08, Vol.23 (15), p.2856-2866

2012

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The Pathobiology of Amyotrophic Lateral Sclerosis: A Proteinopathy?

Journal of neuropathology and experimental neurology, 2005-08, Vol.64 (8), p.649-664

2005

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Searching for novel Cdk5 substrates in brain by comparative phosphoproteomics of wild type and Cdk5-/- mice

PloS one, 2014-03, Vol.9 (3), p.e90363

2014

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Cdk5 inhibitory peptide (CIP) inhibits Cdk5/p25 activity induced by high glucose in pancreatic beta cells and recovers insulin secretion from p25 damage

PloS one, 2013-09, Vol.8 (9), p.e63332-e63332

2013

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Rapid, quantitative therapeutic screening for Alzheimer's enzymes enabled by optimal signal transduction with transistors

Analyst (London), 2020-04, Vol.145 (8), p.2925-2936

2020

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Quantitative phosphoproteomic analysis of neuronal intermediate filament proteins (NF-M/H) in Alzheimer's disease by iTRAQ

The FASEB journal, 2010-11, Vol.24 (11), p.4396-4407

2010

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Cyclin-dependent kinase 5 regulates E2F transcription factor through phosphorylation of Rb protein in neurons

Cell cycle (Georgetown, Tex.), 2012-04, Vol.11 (8), p.1603-1610

2012

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TFP5, a Peptide Inhibitor of Aberrant and Hyperactive Cdk5/p25, Attenuates Pathological Phenotypes and Restores Synaptic Function in CK-p25Tg Mice

Journal of Alzheimer's disease, 2017-01, Vol.56 (1), p.335

2017

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A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons

The EMBO journal, 2004-06, Vol.23 (11), p.2235-2245

2004

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Phosphorylation, Dephosphorylation, and Multiprotein Assemblies Regulate Dynamic Behavior of Neuronal Cytoskeleton: A Mini-Review

Frontiers in molecular neuroscience, 2018-10, Vol.11, p.373-373

2018

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Deregulated Cdk5 Activity Is Involved in Inducing Alzheimer’s Disease

Archives of medical research, 2012-11, Vol.43 (8), p.655-662

2012

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Peptidyl-Prolyl Isomerase 1 Regulates Protein Phosphatase 2A-Mediated Topographic Phosphorylation of Neurofilament Proteins

The Journal of neuroscience, 2009-11, Vol.29 (47), p.14869-14880

2009

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Phosphorylation-specific peptidyl-prolyl isomerization of neuronal cytoskeletal proteins by Pin1: implications for therapeutics in neurodegeneration

Journal of Alzheimer's disease, 2010-01, Vol.19 (2), p.389

2010

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Cyclin-Dependent Kinase 5 Modulates the Transcriptional Activity of the Mineralocorticoid Receptor and Regulates Expression of Brain-Derived Neurotrophic Factor

Molecular endocrinology (Baltimore, Md.), 2010-05, Vol.24 (5), p.941-952

2010

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Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1

Proceedings of the National Academy of Sciences - PNAS, 2007-01, Vol.104 (2), p.660-665

2007

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Cyclin-Dependent Kinase 5 Activity Regulates Pain Signaling

Proceedings of the National Academy of Sciences - PNAS, 2006-01, Vol.103 (3), p.791-796

2006

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Investigation of the potential off-target effects on Munc 18 (p67) involved in synaptic vesical transport due to the interaction with peptide p5

Biophysical journal, 2023-02, Vol.122 (3), p.333a-333a

2023

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Cyclin-Dependent Kinase 5 Phosphorylation of Human Septin SEPT5 (hCDCrel-1) Modulates Exocytosis

The Journal of neuroscience, 2008-04, Vol.28 (14), p.3631-3643

2008

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Investigation of the Effect of Peptide p5 Targeting CDK5-p25 Hyperactivity on Munc18–1 (P67) Regulating Neuronal Exocytosis Using Molecular Simulations

Biochemistry (Easton), 2024-07, Vol.63 (14), p.1837-1857

2024

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Targeting Cdk5 Activity in Neuronal Degeneration and Regeneration

Cellular and molecular neurobiology, 2009-12, Vol.29 (8), p.1073-1080

2009

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Cyclin-dependent Kinase-5 Is Involved in Neuregulin-dependent Activation of Phosphatidylinositol 3-Kinase and Akt Activity Mediating Neuronal Survival

The Journal of biological chemistry, 2003-09, Vol.278 (37), p.35702-35709

2003

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Cdk5 Regulates the Organization of Nestin and Its Association with p35

Molecular and Cellular Biology, 2003-07, Vol.23 (14), p.5090-5106

2003

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Direct evidence of phosphorylated neuronal intermediate filament proteins in neurofibrillary tangles (NFTs): phosphoproteomics of Alzheimer's NFTs

Overexpression of the Cdk5 inhibitory peptide in motor neurons rescue of amyotrophic lateral sclerosis phenotype in a mouse model

Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments

Achaete-scute homologue-1 (ASH1) stimulates migration of lung cancer cells through Cdk5/p35 pathway

The Pathobiology of Amyotrophic Lateral Sclerosis: A Proteinopathy?

Searching for novel Cdk5 substrates in brain by comparative phosphoproteomics of wild type and Cdk5-/- mice

Cdk5 inhibitory peptide (CIP) inhibits Cdk5/p25 activity induced by high glucose in pancreatic beta cells and recovers insulin secretion from p25 damage

Rapid, quantitative therapeutic screening for Alzheimer's enzymes enabled by optimal signal transduction with transistors

Quantitative phosphoproteomic analysis of neuronal intermediate filament proteins (NF-M/H) in Alzheimer's disease by iTRAQ

Cyclin-dependent kinase 5 regulates E2F transcription factor through phosphorylation of Rb protein in neurons

TFP5, a Peptide Inhibitor of Aberrant and Hyperactive Cdk5/p25, Attenuates Pathological Phenotypes and Restores Synaptic Function in CK-p25Tg Mice

A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons

Phosphorylation, Dephosphorylation, and Multiprotein Assemblies Regulate Dynamic Behavior of Neuronal Cytoskeleton: A Mini-Review

Deregulated Cdk5 Activity Is Involved in Inducing Alzheimer’s Disease

Peptidyl-Prolyl Isomerase 1 Regulates Protein Phosphatase 2A-Mediated Topographic Phosphorylation of Neurofilament Proteins

Phosphorylation-specific peptidyl-prolyl isomerization of neuronal cytoskeletal proteins by Pin1: implications for therapeutics in neurodegeneration

Cyclin-Dependent Kinase 5 Modulates the Transcriptional Activity of the Mineralocorticoid Receptor and Regulates Expression of Brain-Derived Neurotrophic Factor

Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1

Cyclin-Dependent Kinase 5 Activity Regulates Pain Signaling

Investigation of the potential off-target effects on Munc 18 (p67) involved in synaptic vesical transport due to the interaction with peptide p5

Cyclin-Dependent Kinase 5 Phosphorylation of Human Septin SEPT5 (hCDCrel-1) Modulates Exocytosis

Investigation of the Effect of Peptide p5 Targeting CDK5-p25 Hyperactivity on Munc18–1 (P67) Regulating Neuronal Exocytosis Using Molecular Simulations

Targeting Cdk5 Activity in Neuronal Degeneration and Regeneration

Cyclin-dependent Kinase-5 Is Involved in Neuregulin-dependent Activation of Phosphatidylinositol 3-Kinase and Akt Activity Mediating Neuronal Survival

Cdk5 Regulates the Organization of Nestin and Its Association with p35

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