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U.S. Food and Drug Administration Approval: Carfilzomib for the Treatment of Multiple Myeloma

Clinical cancer research, 2013-09, Vol.19 (17), p.4559-4563

2013

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FDA Approval of Palbociclib in Combination with Fulvestrant for the Treatment of Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer

Clinical cancer research, 2016-10, Vol.22 (20), p.4968-4972

2016

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FDA Approval Summary: Rucaparib for the Treatment of Patients with Deleterious BRCA Mutation-Associated Advanced Ovarian Cancer

Clinical cancer research, 2017-12, Vol.23 (23), p.7165-7170

2017

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U.S. Food and Drug Administration Approval: Neratinib for the Extended Adjuvant Treatment of Early-Stage HER2-Positive Breast Cancer

Clinical cancer research, 2018-08, Vol.24 (15), p.3486-3491

2018

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FDA Approval: Ribociclib for the Treatment of Postmenopausal Women with Hormone Receptor-Positive, HER2-Negative Advanced or Metastatic Breast Cancer

Clinical cancer research, 2018-07, Vol.24 (13), p.2999-3004

2018

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U.S. Food and Drug Administration Approval: Vismodegib for Recurrent, Locally Advanced, or Metastatic Basal Cell Carcinoma

Clinical cancer research, 2013-05, Vol.19 (9), p.2289-2293

2013

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essential role for Rac1 in endothelial cell function and vascular development

The FASEB journal, 2008-06, Vol.22 (6), p.1829-1838

2008

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Semaphorin 3E Initiates Antiangiogenic Signaling through Plexin D1 by Regulating Arf6 and R-Ras

Molecular and Cellular Biology, 2010-06, Vol.30 (12), p.3086-3098

2010

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Radium Ra 223 Dichloride Injection: U.S. Food and Drug Administration Drug Approval Summary

Clinical cancer research, 2014, Vol.20 (1), p.9-14

2014

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Decoding kinase-adverse event associations for small molecule kinase inhibitors

Nature communications, 2022-07, Vol.13 (1), p.4349-4349, Article 4349

2022

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FDA Approval: Uridine Triacetate for the Treatment of Patients Following Fluorouracil or Capecitabine Overdose or Exhibiting Early-Onset Severe Toxicities Following Administration of These Drugs

Clinical cancer research, 2016-09, Vol.22 (18), p.4545-4549

2016

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U.S. Food and Drug Administration Approval: Cabozantinib for the Treatment of Advanced Renal Cell Carcinoma

Clinical cancer research, 2017-01, Vol.23 (2), p.330-335

2017

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PDZ-RhoGEF and LARG Are Essential for Embryonic Development and Provide a Link between Thrombin and LPA Receptors and Rho Activation

The Journal of biological chemistry, 2013-04, Vol.288 (17), p.12232-12243

2013

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Nonclinical Evaluations of Small-Molecule Oncology Drugs: Integration into Clinical Dose Optimization and Toxicity Management

Clinical cancer research, 2016-06, Vol.22 (11), p.2618-2622

2016

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Multiple PPPS/TP motifs act in a combinatorial fashion to transduce Wnt signaling through LRP6

FEBS letters, 2008-01, Vol.582 (2), p.255-261

2008

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FDA Approval Summary: Olaparib Monotherapy in Patients with Deleterious Germline BRCA-Mutated Advanced Ovarian Cancer Treated with Three or More Lines of Chemotherapy

Clinical cancer research, 2015-10, Vol.21 (19), p.4257-4261

2015

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Cellular N-Ras Promotes Cell Survival by Downregulation of Jun N-Terminal Protein Kinase and p38

Molecular and Cellular Biology, 2002-03, Vol.22 (5), p.1589-1606

2002

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FDA Approval: Palbociclib for the Treatment of Postmenopausal Patients with Estrogen Receptor-Positive, HER2-Negative Metastatic Breast Cancer

Clinical cancer research, 2015-11, Vol.21 (21), p.4760-4766

2015

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FDA Approval Summary: Atezolizumab for the Treatment of Patients with Progressive Advanced Urothelial Carcinoma after Platinum‐Containing Chemotherapy

The oncologist (Dayton, Ohio), 2017-06, Vol.22 (6), p.743-749

2017

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21st Century Cardio-Oncology

JACC. Basic to translational science, 2016-08, Vol.1 (5), p.386-398

2016

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Critical Role of the Pleckstrin Homology and Cysteine-rich Domains in Vav Signaling and Transforming Activity

The Journal of biological chemistry, 2002-10, Vol.277 (42), p.39350-39359

2002

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Vav transformation requires activation of multiple GTPases and regulation of gene expression

Molecular cancer research, 2004-12, Vol.2 (12), p.702-711

2004

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FDA Approval: Ado-Trastuzumab Emtansine for the Treatment of Patients with HER2-Positive Metastatic Breast Cancer

Clinical cancer research, 2014-09, Vol.20 (17), p.4436-4441

2014

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Abiraterone Acetate in Combination with Prednisone for the Treatment of Patients with Metastatic Castration-Resistant Prostate Cancer: U.S. Food and Drug Administration Drug Approval Summary

Clinical cancer research, 2013-12, Vol.19 (24), p.6650-6656

2013

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U.S. Food and Drug Administration Approval: Carfilzomib for the Treatment of Multiple Myeloma

FDA Approval of Palbociclib in Combination with Fulvestrant for the Treatment of Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer

FDA Approval Summary: Rucaparib for the Treatment of Patients with Deleterious BRCA Mutation-Associated Advanced Ovarian Cancer

U.S. Food and Drug Administration Approval: Neratinib for the Extended Adjuvant Treatment of Early-Stage HER2-Positive Breast Cancer

FDA Approval Summary: Niraparib for the Maintenance Treatment of Patients with Recurrent Ovarian Cancer in Response to Platinum-Based Chemotherapy

FDA Approval: Ribociclib for the Treatment of Postmenopausal Women with Hormone Receptor-Positive, HER2-Negative Advanced or Metastatic Breast Cancer

U.S. Food and Drug Administration Approval: Vismodegib for Recurrent, Locally Advanced, or Metastatic Basal Cell Carcinoma

essential role for Rac1 in endothelial cell function and vascular development

Semaphorin 3E Initiates Antiangiogenic Signaling through Plexin D1 by Regulating Arf6 and R-Ras

Radium Ra 223 Dichloride Injection: U.S. Food and Drug Administration Drug Approval Summary

Decoding kinase-adverse event associations for small molecule kinase inhibitors

FDA Approval: Uridine Triacetate for the Treatment of Patients Following Fluorouracil or Capecitabine Overdose or Exhibiting Early-Onset Severe Toxicities Following Administration of These Drugs

U.S. Food and Drug Administration Approval: Cabozantinib for the Treatment of Advanced Renal Cell Carcinoma

PDZ-RhoGEF and LARG Are Essential for Embryonic Development and Provide a Link between Thrombin and LPA Receptors and Rho Activation

Nonclinical Evaluations of Small-Molecule Oncology Drugs: Integration into Clinical Dose Optimization and Toxicity Management

Multiple PPPS/TP motifs act in a combinatorial fashion to transduce Wnt signaling through LRP6

FDA Approval Summary: Olaparib Monotherapy in Patients with Deleterious Germline BRCA-Mutated Advanced Ovarian Cancer Treated with Three or More Lines of Chemotherapy

Cellular N-Ras Promotes Cell Survival by Downregulation of Jun N-Terminal Protein Kinase and p38

FDA Approval: Palbociclib for the Treatment of Postmenopausal Patients with Estrogen Receptor-Positive, HER2-Negative Metastatic Breast Cancer

FDA Approval Summary: Atezolizumab for the Treatment of Patients with Progressive Advanced Urothelial Carcinoma after Platinum‐Containing Chemotherapy

21st Century Cardio-Oncology

Critical Role of the Pleckstrin Homology and Cysteine-rich Domains in Vav Signaling and Transforming Activity

Vav transformation requires activation of multiple GTPases and regulation of gene expression

FDA Approval: Ado-Trastuzumab Emtansine for the Treatment of Patients with HER2-Positive Metastatic Breast Cancer

Abiraterone Acetate in Combination with Prednisone for the Treatment of Patients with Metastatic Castration-Resistant Prostate Cancer: U.S. Food and Drug Administration Drug Approval Summary

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