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A new versatile and diastereoselective synthesis of polysubstituted 2-oxopiperazines from naturally occurring amino acids

Tetrahedron: asymmetry, 2007-11, Vol.18 (22), p.2680-2688

2007

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An Optimized Scalable Fully Automated Solid-Phase Microwave-Assisted cGMP-Ready Process for the Preparation of Eptifibatide

Organic process research & development, 2021-03, Vol.25 (3), p.552-563

2021

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An Optimized Safe Process from Bench to Pilot cGMP Production of API Eptifibatide Using a Multigram-Scale Microwave-Assisted Solid-Phase Peptide Synthesizer

Organic process research & development, 2021-12, Vol.25 (12), p.2754-2771

2021

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Corrections to “An Optimized Safe Process from Bench to Pilot cGMP Production of API Eptifibatide Using a Multigram-Scale Microwave-Assisted Solid-Phase Peptide Synthesizer”

Organic process research & development, 2022-08, Vol.26 (8), p.2540-2540

2022

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Novel analogues of ketamine and phencyclidine as NMDA receptor antagonists

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (7), p.2059-2063

2011

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Stereoselective Synthesis of a Key Intermediate of Sanfetrinem by Means of a Chelated Tin(IV) Enolate

Journal of organic chemistry, 1997-03, Vol.62 (6), p.1653-1661

1997

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First synthesis of 4-chloro-2,2-difluoro[1,3]dioxole[4,5- c]pyridine

Tetrahedron letters, 2010-12, Vol.51 (51), p.6783-6785

2010

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Synthesis and Structure–Activity Relationships of α‑Amino-γ-lactone Ketolides: A Novel Class of Macrolide Antibiotics

ACS medicinal chemistry letters, 2014-10, Vol.5 (10), p.1133-1137

2014

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Synthesis of 3-azabicyclo[4.1.0]heptane-1-carboxylic acid

Tetrahedron, 2010-07, Vol.66 (29), p.5492-5497

2010

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Microwave-Assisted Aminocarbonylation of Aryl Bromides at Low Carbon Monoxide Pressure

Synlett, 2009-01, Vol.2009 (1), p.47-50

2009

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Phenylethynyl-pyrrolo[1,2- a]pyrazine: A new potent and selective tool in the mGluR5 antagonists arena

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (6), p.1804-1809

2008

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Synthesis of 5-(3,4-dichlorophenyl)-4-[(methyloxy)methyl]-2-azabicyclo[3.2.1]octane derivatives as constrained aryl-piperidines with activity as triple re-uptake inhibitors

Tetrahedron letters, 2010-10, Vol.51 (42), p.5521-5524

2010

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First synthesis of 2,6-diazabicyclo[3.2.0]heptane derivatives

Tetrahedron letters, 2009-12, Vol.50 (52), p.7280-7282

2009

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Synthesis of 5-(3,4-dichlorophenyl)-4-[(methyloxy)methyl]-2-azabicyclo[3.2.1]oc t ane derivatives as constrained aryl-piperidines with activity as triple re-uptake inhibitors

Tetrahedron letters, 2010-10, Vol.51 (42), p.5521-5524

2010

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Solid supported chiral auxiliaries in asymmetric synthesis. Part 2: Catalysis of 1,3-dipolar cycloadditions by Mg(II) cation

Tetrahedron, 2001-09, Vol.57 (39), p.8313-8322

2001

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Rapid Access to 1-Benzyl 2-Substituted Piperazines: Application to the Synthesis of 1-Benzyl-2-difluoromethyl-Piperazine

Synthetic communications, 2011-07, Vol.41 (14), p.2031-2035

2011

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Synthesis and pharmacological characterization of 5-phenyl-2-[2-(1-piperidinylcarbonyl)phenyl]-2,3-dihydro-1H-pyrrolo[1,2-c]imidazol-1-ones: A new class of Neuropeptide S antagonists

Bioorganic & medicinal chemistry letters, 2010-12, Vol.20 (24), p.7308-7311

2010

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Synthesis of new polysubstituted piperazines and dihydro-2H-pyrazines by selective reduction of 2-oxo-piperazines

Tetrahedron: asymmetry, 2010-02, Vol.21 (2), p.191-194

2010

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Synthesis of new polysubstituted piperazines and dihydro-2 H-pyrazines by selective reduction of 2-oxo-piperazines

Tetrahedron: asymmetry, 2010, Vol.21 (2), p.191-194

2010

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Deprotection of o-Nitrobenzensulfonyl (Nosyl) Derivatives of Amines Mediated by a Solid-Supported Thiol

Synlett, 2005-12, Vol.2005 (19), p.2996-2998

2005

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(4 S)- p-Hydroxybenzyl-1,3-oxazolidin-2-one as a solid-supported chiral auxiliary in asymmetric 1,3-dipolar cycloadditions

Tetrahedron letters, 2000-02, Vol.41 (8), p.1265-1269

2000

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Synthesis and pharmacological characterization of 5-phenyl-2-[2-(1-piperidinylcarbonyl)phenyl]-2,3-dihydro-1H-pyr rolo[1,2-c]imidazol-1-ones: A new class of Neuropeptide S antagonists

Bioorganic & medicinal chemistry letters, 2010-12, Vol.20 (24), p.7308-7311

2010

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Synthesis and pharmacological characterization of 5-phenyl-2-[2-(1-piperidinylcarbonyl)phenyl]-2,3-dihydro-1 H-pyrrolo[1,2- c]imidazol-1-ones: A new class of Neuropeptide S antagonists

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (24), p.7308-7311

2010

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Solid-Supported Nitrile Oxides as Stable and Valuable Reactive Intermediates

European journal of organic chemistry, 2002-04, Vol.2002 (7), p.1175-1183

2002

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Synthesis and pharmacological characterisation of 2,4-Dicarboxy-pyrroles as selective non-Competitive mGluR1 antagonists

Bioorganic & medicinal chemistry, 2003-01, Vol.11 (2), p.171-183

2003

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A new versatile and diastereoselective synthesis of polysubstituted 2-oxopiperazines from naturally occurring amino acids

An Optimized Scalable Fully Automated Solid-Phase Microwave-Assisted cGMP-Ready Process for the Preparation of Eptifibatide

An Optimized Safe Process from Bench to Pilot cGMP Production of API Eptifibatide Using a Multigram-Scale Microwave-Assisted Solid-Phase Peptide Synthesizer

Corrections to “An Optimized Safe Process from Bench to Pilot cGMP Production of API Eptifibatide Using a Multigram-Scale Microwave-Assisted Solid-Phase Peptide Synthesizer”

Novel analogues of ketamine and phencyclidine as NMDA receptor antagonists

Stereoselective Synthesis of a Key Intermediate of Sanfetrinem by Means of a Chelated Tin(IV) Enolate

First synthesis of 4-chloro-2,2-difluoro[1,3]dioxole[4,5- c]pyridine

Synthesis and Structure–Activity Relationships of α‑Amino-γ-lactone Ketolides: A Novel Class of Macrolide Antibiotics

Synthesis of 3-azabicyclo[4.1.0]heptane-1-carboxylic acid

Microwave-Assisted Aminocarbonylation of Aryl Bromides at Low Carbon Monoxide Pressure

Phenylethynyl-pyrrolo[1,2- a]pyrazine: A new potent and selective tool in the mGluR5 antagonists arena

Synthesis of 5-(3,4-dichlorophenyl)-4-[(methyloxy)methyl]-2-azabicyclo[3.2.1]octane derivatives as constrained aryl-piperidines with activity as triple re-uptake inhibitors

First synthesis of 2,6-diazabicyclo[3.2.0]heptane derivatives

Synthesis of 5-(3,4-dichlorophenyl)-4-[(methyloxy)methyl]-2-azabicyclo[3.2.1]oc t ane derivatives as constrained aryl-piperidines with activity as triple re-uptake inhibitors

Solid supported chiral auxiliaries in asymmetric synthesis. Part 2: Catalysis of 1,3-dipolar cycloadditions by Mg(II) cation

Rapid Access to 1-Benzyl 2-Substituted Piperazines: Application to the Synthesis of 1-Benzyl-2-difluoromethyl-Piperazine

Synthesis and pharmacological characterization of 5-phenyl-2-[2-(1-piperidinylcarbonyl)phenyl]-2,3-dihydro-1H-pyrrolo[1,2-c]imidazol-1-ones: A new class of Neuropeptide S antagonists

Synthesis of new polysubstituted piperazines and dihydro-2H-pyrazines by selective reduction of 2-oxo-piperazines

Synthesis of new polysubstituted piperazines and dihydro-2 H-pyrazines by selective reduction of 2-oxo-piperazines

Deprotection of o-Nitrobenzensulfonyl (Nosyl) Derivatives of Amines Mediated by a Solid-Supported Thiol

(4 S)- p-Hydroxybenzyl-1,3-oxazolidin-2-one as a solid-supported chiral auxiliary in asymmetric 1,3-dipolar cycloadditions

Synthesis and pharmacological characterization of 5-phenyl-2-[2-(1-piperidinylcarbonyl)phenyl]-2,3-dihydro-1H-pyr rolo[1,2-c]imidazol-1-ones: A new class of Neuropeptide S antagonists

Synthesis and pharmacological characterization of 5-phenyl-2-[2-(1-piperidinylcarbonyl)phenyl]-2,3-dihydro-1 H-pyrrolo[1,2- c]imidazol-1-ones: A new class of Neuropeptide S antagonists

Solid-Supported Nitrile Oxides as Stable and Valuable Reactive Intermediates

Synthesis and pharmacological characterisation of 2,4-Dicarboxy-pyrroles as selective non-Competitive mGluR1 antagonists

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