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Inhibition of the MAP kinase ERK protects from lipopolysaccharide-induced lung injury

Biochemical pharmacology, 2009-06, Vol.77 (12), p.1827-1834

2009

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Efficacy of drugs used in the treatment of IBD and combinations thereof in acute DSS-induced colitis in mice

Life sciences (1973), 2013-04, Vol.92 (12), p.708-718

2013

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TP53 loss creates therapeutic vulnerability in colorectal cancer

Nature (London), 2015-04, Vol.520 (7549), p.697-701

2015

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Cytochrome P450 2C19 681G>A Polymorphism and High On-Clopidogrel Platelet Reactivity Associated With Adverse 1-Year Clinical Outcome of Elective Percutaneous Coronary Intervention With Drug-Eluting or Bare-Metal Stents

Journal of the American College of Cardiology, 2008-05, Vol.51 (20), p.1925-1934

2008

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Iodine-Mediated Tryptathionine Formation Facilitates the Synthesis of Amanitins

Journal of the American Chemical Society, 2021-09, Vol.143 (35), p.14322-14331

2021

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Label-Free in Situ Monitoring of Histone Deacetylase Drug Target Engagement by Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry Biotyping and Imaging

Analytical chemistry (Washington), 2014-05, Vol.86 (10), p.4642-4647

2014

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Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting

Beilstein journal of organic chemistry, 2018-02, Vol.14 (1), p.407-415

2018

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Spinal inflammatory hyperalgesia is mediated by prostaglandin E receptors of the EP2 subtype

The Journal of clinical investigation, 2005-03, Vol.115 (3), p.673-679

2005

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Regulation of MMP-9 by a WIN-binding site in the monocyte-macrophage system independent from cannabinoid receptors

PloS one, 2012-11, Vol.7 (11), p.e48272

2012

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Lipopolysaccharide-induced lung inflammation is inhibited by neutralization of GM-CSF

European journal of pharmacology, 2007-02, Vol.557 (2), p.230-235

2007

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Inhibitors of mitogen-activated protein kinases differentially regulate costimulated T cell cytokine production and mouse airway eosinophilia

Respiratory research, 2005-04, Vol.6 (1), p.36-36, Article 36

2005

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Amanitins and their development as a payload for antibody-drug conjugates

Drug discovery today. Technologies, 2018-12, Vol.30, p.85-89

2018

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Cytokine profiles of cord and adult blood leukocytes: differences in expression are due to differences in expression and activation of transcription factors

BMC immunology, 2007-08, Vol.8 (1), p.18-18, Article 18

2007

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Enhancing the Pharmacokinetics and Antitumor Activity of an α‑Amanitin-Based Small-Molecule Drug Conjugate via Conjugation with an Fc Domain

Journal of medicinal chemistry, 2021-04, Vol.64 (7), p.4117-4129

2021

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Quantitative Detection of Borrelia burgdorferi by Real-Time PCR

Journal of Clinical Microbiology, 1999-06, Vol.37 (6), p.1958-1963

1999

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Total Synthesis of α‐ and β‐Amanitin

Angewandte Chemie International Edition, 2020-07, Vol.59 (28), p.11390-11393

International ed. in English, 2020

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Suppressed Injury-Induced Rise in Spinal Prostaglandin E2 Production and Reduced Early Thermal Hyperalgesia in iNOS-Deficient Mice

The Journal of neuroscience, 2000-09, Vol.20 (17), p.6714-6720

2000

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Abstract 910: Amanitin-based ADCs targeting PSMA as novel therapeutic modality for prostate cancer therapy

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.910-910

2021

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Abstract 915: Preclinical evaluation of anti-CD37 antibody-targeted amanitin conjugates (ATAC) in B-cell malignancies

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.915-915

2021

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Pharmacogenomics of asthma

Current pharmaceutical design, 2006-09, Vol.12 (25), p.3195-3206

2006

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A First in Human Study Planned to Evaluate Hdp-101, an Anti-BCMA Amanitin Antibody-Drug Conjugate with a New Payload and a New Mode of Action, in Multiple Myeloma

Blood, 2020-11, Vol.136 (Supplement 1), p.34-34

2020

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Site-specific modification of native IgGs with flexible drug-load

Chembiochem : a European journal of chemical biology, 2024-09, p.e202400511

2024

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HDP-101, an Anti-BCMA Antibody-Drug Conjugate, Safely Delivers Amanitin to Induce Cell Death in Proliferating and Resting Multiple Myeloma Cells

Molecular cancer therapeutics, 2021-02, Vol.20 (2), p.367-378

2021

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Hdp-101, an Anti-BCMA Antibody-Drug Conjugate with a Novel Payload Amanitin in Patients with Relapsed Multiple Myeloma, Initial Findings of the First in Human Study

Blood, 2022-11, Vol.140 (Supplement 1), p.7235-7236

2022

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Regulation of IL‐13 synthesis in human lymphocytes: implications for asthma therapy

British journal of pharmacology, 2002-04, Vol.135 (8), p.1915-1926

2002

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Inhibition of the MAP kinase ERK protects from lipopolysaccharide-induced lung injury

Efficacy of drugs used in the treatment of IBD and combinations thereof in acute DSS-induced colitis in mice

TP53 loss creates therapeutic vulnerability in colorectal cancer

Cytochrome P450 2C19 681G>A Polymorphism and High On-Clopidogrel Platelet Reactivity Associated With Adverse 1-Year Clinical Outcome of Elective Percutaneous Coronary Intervention With Drug-Eluting or Bare-Metal Stents

Iodine-Mediated Tryptathionine Formation Facilitates the Synthesis of Amanitins

Label-Free in Situ Monitoring of Histone Deacetylase Drug Target Engagement by Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry Biotyping and Imaging

Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting

Spinal inflammatory hyperalgesia is mediated by prostaglandin E receptors of the EP2 subtype

Regulation of MMP-9 by a WIN-binding site in the monocyte-macrophage system independent from cannabinoid receptors

Lipopolysaccharide-induced lung inflammation is inhibited by neutralization of GM-CSF

Inhibitors of mitogen-activated protein kinases differentially regulate costimulated T cell cytokine production and mouse airway eosinophilia

Amanitins and their development as a payload for antibody-drug conjugates

Cytokine profiles of cord and adult blood leukocytes: differences in expression are due to differences in expression and activation of transcription factors

Enhancing the Pharmacokinetics and Antitumor Activity of an α‑Amanitin-Based Small-Molecule Drug Conjugate via Conjugation with an Fc Domain

Quantitative Detection of Borrelia burgdorferi by Real-Time PCR

Total Synthesis of α‐ and β‐Amanitin

Suppressed Injury-Induced Rise in Spinal Prostaglandin E2 Production and Reduced Early Thermal Hyperalgesia in iNOS-Deficient Mice

Abstract 910: Amanitin-based ADCs targeting PSMA as novel therapeutic modality for prostate cancer therapy

Abstract 915: Preclinical evaluation of anti-CD37 antibody-targeted amanitin conjugates (ATAC) in B-cell malignancies

Pharmacogenomics of asthma

A First in Human Study Planned to Evaluate Hdp-101, an Anti-BCMA Amanitin Antibody-Drug Conjugate with a New Payload and a New Mode of Action, in Multiple Myeloma

Site-specific modification of native IgGs with flexible drug-load

HDP-101, an Anti-BCMA Antibody-Drug Conjugate, Safely Delivers Amanitin to Induce Cell Death in Proliferating and Resting Multiple Myeloma Cells

Hdp-101, an Anti-BCMA Antibody-Drug Conjugate with a Novel Payload Amanitin in Patients with Relapsed Multiple Myeloma, Initial Findings of the First in Human Study

Regulation of IL‐13 synthesis in human lymphocytes: implications for asthma therapy

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