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Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL

Nature medicine, 2013-03, Vol.19 (3), p.368-371

2013

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Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

Proceedings of the National Academy of Sciences - PNAS, 2016-10, Vol.113 (40), p.11306-11311

2016

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Either IL-7 activation of JAK-STAT or BEZ inhibition of PI3K-AKT-mTOR pathways dominates the single-cell phosphosignature of ex vivo treated pediatric T-cell acute lymphoblastic leukemia cells

Haematologica (Roma), 2022-06, Vol.107 (6), p.1293

2022

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Genetic loss of SH2B3 in acute lymphoblastic leukemia

Blood, 2013-10, Vol.122 (14), p.2425-2432

2013

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CircFBXW7 in patients with T-cell ALL: depletion sustains MYC and NOTCH activation and leukemia cell viability

Experimental hematology & oncology, 2023-01, Vol.12 (1), p.12-12, Article 12

2023

Volltextzugriff (PDF)

Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia

Blood reviews, 2011-03, Vol.25 (2), p.83-90

2011

Volltextzugriff (PDF)

DNA methyltransferase 3a hot-spot locus is not mutated in pediatric patients affected by acute myeloid or T-cell acute lymphoblastic leukemia: an Italian study

Haematologica (Roma), 2011-12, Vol.96 (12), p.1886-1887

2011

Volltextzugriff (PDF)

Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia

Nature (London), 2018-01, Vol.553 (7689), p.511-514

2018

Volltextzugriff (PDF)

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

Nature genetics, 2011-10, Vol.43 (10), p.932-939

2011

Volltextzugriff (PDF)

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

Clinical cancer research, 2019-01, Vol.25 (1), p.222-239

2019

Volltextzugriff (PDF)

The presence of mutated and deleted PTEN is associated with an increased risk of relapse in childhood T cell acute lymphoblastic leukaemia treated with AIEOP‐BFM ALL protocols

British journal of haematology, 2018-09, Vol.182 (5), p.705-711

2018

Volltextzugriff (PDF)

Phf6 Loss Enhances HSC Self-Renewal Driving Tumor Initiation and Leukemia Stem Cell Activity in T-ALL

Cancer discovery, 2019-03, Vol.9 (3), p.436-451

2019

Volltextzugriff (PDF)

Long-Term Outcome of Relapsed Acute T-Lymphoblastic Leukemia (T-ALL) in Children and Adolescents

Blood, 2019-11, Vol.134 (Supplement_1), p.2580-2580

2019

Volltextzugriff (PDF)

Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Cancer discovery, 2020-09, Vol.10 (9), p.1388-1409

2020

Volltextzugriff (PDF)

Large-scale circular RNA deregulation in T-ALL: unlocking unique ectopic expression of molecular subtypes

Blood advances, 2020-12, Vol.4 (23), p.5902-5914

2020

Volltextzugriff (PDF)

Postinduction minimal residual disease monitoring by polymerase chain reaction in children with acute lymphoblastic leukemia

Journal of clinical oncology, 2014-11, Vol.32 (31), p.3553-3558

2014

Volltextzugriff (PDF)

Next‐generation sequencing of PTEN mutations for monitoring minimal residual disease in T‐cell acute lymphoblastic leukemia

Pediatric blood & cancer, 2020-01, Vol.67 (1), p.e28025-n/a

2020

Volltextzugriff (PDF)

Clonal Evolution Mechanisms and Collateral Sensitivity to Impdh Inhibitor Therapy in Relapsed Lymphoblastic Leukemia

Blood, 2017-12, Vol.130, p.2602-2602

2017

Volltextzugriff (PDF)

ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia

Oncotarget, 2017-04, Vol.8 (16), p.26129-26141

2017

Volltextzugriff (PDF)

WT1 mutations in T-ALL

Blood, 2009-07, Vol.114 (5), p.1038-1045

2009

Volltextzugriff (PDF)

A Case of T-cell Acute Lymphoblastic Leukemia Relapsed As Myeloid Acute Leukemia

Pediatric blood & cancer, 2016-09, Vol.63 (9), p.1660-1663

2016

Volltextzugriff (PDF)

Loss of PTEN in Pediatric T-Cell Acute Lymphoblastic Leukemia Patients: Proteomic and Molecular Characterization

Blood, 2014-12, Vol.124 (21), p.2408-2408

2014

Volltextzugriff (PDF)

Minimal Residual Disease Monitoring In Acute Lymphoblastic Leukemia Patients Using Immune Receptor Sequencing

Blood, 2013-11, Vol.122 (21), p.1381-1381

2013

Volltextzugriff (PDF)

Extracellular ATP signaling during differentiation of C2C12 skeletal muscle cells: role in proliferation

Molecular and cellular biochemistry, 2011-05, Vol.351 (1-2), p.183-196

2011

Volltextzugriff (PDF)

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Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

Either IL-7 activation of JAK-STAT or BEZ inhibition of PI3K-AKT-mTOR pathways dominates the single-cell phosphosignature of ex vivo treated pediatric T-cell acute lymphoblastic leukemia cells

Genetic loss of SH2B3 in acute lymphoblastic leukemia

CircFBXW7 in patients with T-cell ALL: depletion sustains MYC and NOTCH activation and leukemia cell viability

Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia

DNA methyltransferase 3a hot-spot locus is not mutated in pediatric patients affected by acute myeloid or T-cell acute lymphoblastic leukemia: an Italian study

Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

The presence of mutated and deleted PTEN is associated with an increased risk of relapse in childhood T cell acute lymphoblastic leukaemia treated with AIEOP‐BFM ALL protocols

Phf6 Loss Enhances HSC Self-Renewal Driving Tumor Initiation and Leukemia Stem Cell Activity in T-ALL

Long-Term Outcome of Relapsed Acute T-Lymphoblastic Leukemia (T-ALL) in Children and Adolescents

Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Large-scale circular RNA deregulation in T-ALL: unlocking unique ectopic expression of molecular subtypes

Postinduction minimal residual disease monitoring by polymerase chain reaction in children with acute lymphoblastic leukemia

Next‐generation sequencing of PTEN mutations for monitoring minimal residual disease in T‐cell acute lymphoblastic leukemia

Clonal Evolution Mechanisms and Collateral Sensitivity to Impdh Inhibitor Therapy in Relapsed Lymphoblastic Leukemia

ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia

WT1 mutations in T-ALL

Mutational and functional genetics mapping of chemotherapy resistance mechanisms in relapsed acute lymphoblastic leukemia

A Case of T-cell Acute Lymphoblastic Leukemia Relapsed As Myeloid Acute Leukemia

Loss of PTEN in Pediatric T-Cell Acute Lymphoblastic Leukemia Patients: Proteomic and Molecular Characterization

Minimal Residual Disease Monitoring In Acute Lymphoblastic Leukemia Patients Using Immune Receptor Sequencing

Extracellular ATP signaling during differentiation of C2C12 skeletal muscle cells: role in proliferation

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