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Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion

Experimental and Molecular Medicine, 2021, 53(0), , pp.1-17

2021

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Identification of novel discoidin domain receptor 1 (DDR1) inhibitors using E-pharmacophore modeling, structure-based virtual screening, molecular dynamics simulation and MM-GBSA approaches

Computers in biology and medicine, 2022-03, Vol.142, p.105217-105217, Article 105217

2022

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Levosimendan inhibits disulfide tau oligomerization and ameliorates tau pathology in TauP301L-BiFC mice

Experimental and Molecular Medicine, 2023, 55(0), , pp.612-627

2023

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Investigation of Molecular Details of Keap1-Nrf2 Inhibitors Using Molecular Dynamics and Umbrella Sampling Techniques

Molecules (Basel, Switzerland), 2019-11, Vol.24 (22), p.4085

2019

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5- and 6-Exocyclic Products, cis-2,3,5-Trisubstituted Tetrahydrofurans, and cis-2,3,6-Trisubstituted Tetrahydropyrans via Prins-Type Cyclization

Journal of organic chemistry, 2008-10, Vol.73 (19), p.7467-7471

2008

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Mitochondrial dysfunction and Alzheimer's disease: prospects for therapeutic intervention

BMB Reports, 2020, 53(1), , pp.47-55

2020

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Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal model

Neuropharmacology, 2020-05, Vol.167, p.107989, Article 107989

2020

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Synthesis and Biological Evaluation of 2-Substituted Quinoline 6-Carboxamides as Potential mGluR1 Antagonists for the Treatment of Neuropathic Pain

Chemical and Pharmaceutical Bulletin, 2014/06/01, Vol.62(6), pp.508-518

2014

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Translocator protein (TSPO) ligands for the diagnosis or treatment of neurodegenerative diseases: a patent review (2010-2015; part 1)

Expert opinion on therapeutic patents, 2016-11, Vol.26 (11), p.1325-1351

2016

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Pharmacophore-Based Virtual Screening of Novel Competitive Inhibitors of the Neurodegenerative Disease Target Kynurenine-3-Monooxygenase

Molecules (Basel, Switzerland), 2021-05, Vol.26 (11), p.3314

2021

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Aβ modulates actin cytoskeleton via SHIP2-mediated phosphoinositide metabolism

Scientific reports, 2019-10, Vol.9 (1), p.15557-12, Article 15557

2019

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NeuM: A Neuron‐Selective Probe Incorporates into Live Neuronal Membranes via Enhanced Clathrin‐Mediated Endocytosis in Primary Neurons

Angewandte Chemie International Edition, 2024-01, Vol.63 (3), p.e202312942-n/a

International ed. in English, 2024

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Translocator protein (TSPO) ligands for the diagnosis or treatment of neurodegenerative diseases: a patent review (2010 - 2015; part 2)

Expert opinion on therapeutic patents, 2016-11, Vol.26 (11), p.1353-1366

2016

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Mitochondrial dysfunction and Alzheimer’s disease: prospects for therapeutic intervention

BMB reports, 2020-01, Vol.53 (1), p.47-55

2020

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Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitors

Bioorganic & medicinal chemistry, 2015-10, Vol.23 (19), p.6486-6496

2015

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Structural hybridization for inhibitors of the interaction between NRF2 and Keap1

Bulletin of the Korean Chemical Society, 2022, 43(9), , pp.1088-1092

2022

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Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer's disease

Science advances, 2019-03, Vol.5 (3), p.eaav0316

2019

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TMSOTf-Promoted Addition of Alkynes to Aldehydes: A Novel Synthesis of Chroman-4-ones

European Journal of Organic Chemistry, 2008-11, Vol.2008 (32), p.5461-5469

2008

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Neuroprotective Effects of Ethanol Extract of Polyscias fruticosa (EEPF) against Glutamate-Mediated Neuronal Toxicity in HT22 Cells

International journal of molecular sciences, 2023-02, Vol.24 (4), p.3969

2023

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3-Carene, a Phytoncide from Pine Tree Has a Sleep-enhancing Effect by Targeting the GABAA-benzodiazepine Receptors

Experimental Neurobiology, 2019, 28(5), , pp.593-601

2019

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Antioxidant and Anti-Inflammatory Activities of a Natural Compound, Shizukahenriol, through Nrf2 Activation

Molecules (Basel, Switzerland), 2015-09, Vol.20 (9), p.15989-16003

2015

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Structural determinants for activation of the Tau kinase CDK5 by the serotonin receptor 5-HT7R

Cell communication and signaling, 2024-04, Vol.22 (1), p.233-233, Article 233

2024

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Novel potent blockers for TWIK-1/TREK-1 heterodimers as potential antidepressants

Biomedicine & pharmacotherapy, 2023-09, Vol.165, p.115139-115139, Article 115139

2023

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Synthesis of the Tricyclic Ring Structure of Daphnanes via Intramolecular [4 + 3] Cycloaddition/SmI2‑Pinacol Coupling

Organic letters, 2015-06, Vol.17 (11), p.2672-2675

2015

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Synthesis and Biological Evaluation of Aryloxazole Derivatives as Antimitotic and Vascular-Disrupting Agents for Cancer Therapy

Journal of medicinal chemistry, 2013-11, Vol.56 (22), p.9008-9018

2013

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Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion

Identification of novel discoidin domain receptor 1 (DDR1) inhibitors using E-pharmacophore modeling, structure-based virtual screening, molecular dynamics simulation and MM-GBSA approaches

Levosimendan inhibits disulfide tau oligomerization and ameliorates tau pathology in TauP301L-BiFC mice

Investigation of Molecular Details of Keap1-Nrf2 Inhibitors Using Molecular Dynamics and Umbrella Sampling Techniques

5- and 6-Exocyclic Products, cis-2,3,5-Trisubstituted Tetrahydrofurans, and cis-2,3,6-Trisubstituted Tetrahydropyrans via Prins-Type Cyclization

Mitochondrial dysfunction and Alzheimer's disease: prospects for therapeutic intervention

Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal model

Synthesis and Biological Evaluation of 2-Substituted Quinoline 6-Carboxamides as Potential mGluR1 Antagonists for the Treatment of Neuropathic Pain

Translocator protein (TSPO) ligands for the diagnosis or treatment of neurodegenerative diseases: a patent review (2010-2015; part 1)

Pharmacophore-Based Virtual Screening of Novel Competitive Inhibitors of the Neurodegenerative Disease Target Kynurenine-3-Monooxygenase

Aβ modulates actin cytoskeleton via SHIP2-mediated phosphoinositide metabolism

NeuM: A Neuron‐Selective Probe Incorporates into Live Neuronal Membranes via Enhanced Clathrin‐Mediated Endocytosis in Primary Neurons

Translocator protein (TSPO) ligands for the diagnosis or treatment of neurodegenerative diseases: a patent review (2010 - 2015; part 2)

Mitochondrial dysfunction and Alzheimer’s disease: prospects for therapeutic intervention

Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitors

Structural hybridization for inhibitors of the interaction between NRF2 and Keap1

Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer's disease

TMSOTf-Promoted Addition of Alkynes to Aldehydes: A Novel Synthesis of Chroman-4-ones

Neuroprotective Effects of Ethanol Extract of Polyscias fruticosa (EEPF) against Glutamate-Mediated Neuronal Toxicity in HT22 Cells

3-Carene, a Phytoncide from Pine Tree Has a Sleep-enhancing Effect by Targeting the GABAA-benzodiazepine Receptors

Antioxidant and Anti-Inflammatory Activities of a Natural Compound, Shizukahenriol, through Nrf2 Activation

Structural determinants for activation of the Tau kinase CDK5 by the serotonin receptor 5-HT7R

Novel potent blockers for TWIK-1/TREK-1 heterodimers as potential antidepressants

Synthesis of the Tricyclic Ring Structure of Daphnanes via Intramolecular [4 + 3] Cycloaddition/SmI2‑Pinacol Coupling

Synthesis and Biological Evaluation of Aryloxazole Derivatives as Antimitotic and Vascular-Disrupting Agents for Cancer Therapy

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