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Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

Journal of medicinal chemistry, 2008-09, Vol.51 (18), p.5843-5855

2008

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Discovery of 4-((1-(1H-imidazol-2-yl)alkoxy)methyl)pyridines as a new class of Trypanosoma cruzi growth inhibitors

Bioorganic & medicinal chemistry letters, 2020-04, Vol.30 (8), p.127052, Article 127052

2020

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Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides

ACS medicinal chemistry letters, 2019-04, Vol.10 (4), p.481-486

2019

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Ethyl N-(o-Ethynyl)malonanilide as a Useful Building Block for the Preparation of 3,4-Disubstituted-2(1H)-quinolones, 3,4-Disubstituted- and 2,3,4-Trisubstituted Quinolines

Synlett, 1998-04, Vol.1998 (4), p.446-448

1998

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The Palladium-Catalyzed Hydroarylation and Hydrovinylation of Tertiary 3-(o-Acetoxyaryl)- and 3-(o-Benzoyloxyaryl)propynols − A Route to 4-Aryl- and 4-Vinyl-2,2-Dimethyl-3-chromenes

European journal of organic chemistry, 2000-12, Vol.2000 (24), p.4099-4108

2000

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4,5-Dihydroxypyrimidine Carboxamides and N-Alkyl-5-hydroxypyrimidinone Carboxamides Are Potent, Selective HIV Integrase Inhibitors with Good Pharmacokinetic Profiles in Preclinical Species

Journal of medicinal chemistry, 2006-11, Vol.49 (23), p.6646-6649

2006

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A Convenient Synthesis of Nitrogen-Containing Heterocycles Bearing Amino Substituents from Heteroaryl Triflates

Synlett, 1997-12, Vol.12 (12), p.1400-1402

1997

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Electrosynthesis of Aromatic Aldehydes by Palladium-Catalyzed Carbonylation of Aryl Iodides in the Presence of Formic Acid

European journal of organic chemistry, 1999-06, Vol.1999 (6), p.1471-1473

1999

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Discovery of α,γ-Diketo Acids as Potent Selective and Reversible Inhibitors of Hepatitis C Virus NS5b RNA-Dependent RNA Polymerase

Journal of medicinal chemistry, 2004-01, Vol.47 (1), p.14-17

2004

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Palladium-Catalyzed Cyclization of o-Alkynyltrifluoroacetanilides with Allyl Esters. A Regioselective Synthesis of 3-Allylindoles

Journal of organic chemistry, 1998-02, Vol.63 (4), p.1001-1011

1998

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Dihydroxypyrimidine-4-carboxamides as Novel Potent and Selective HIV Integrase Inhibitors

Journal of medicinal chemistry, 2007-05, Vol.50 (9), p.2225-2239

2007

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HCV NS5b RNA-Dependent RNA Polymerase Inhibitors: From α,γ-Diketoacids to 4,5-Dihydroxypyrimidine- or 3-Methyl-5- hydroxypyrimidinonecarboxylic Acids. Design and Synthesis

Journal of medicinal chemistry, 2004-10, Vol.47 (22), p.5336-5339

2004

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Discovery and Synthesis of HIV Integrase Inhibitors: Development of Potent and Orally Bioavailable N-Methyl Pyrimidones

Journal of medicinal chemistry, 2007-10, Vol.50 (20), p.4953-4975

2007

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4-Hydroxy-5-pyrrolinone-3-carboxamide HIV-1 integrase inhibitors

Bioorganic & medicinal chemistry, 2008-07, Vol.18 (14), p.3865-3869

2008

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Novel Macrocyclic Inhibitors of Hepatitis C NS3/4A Protease Featuring a 2-Amino-1,3-thiazole as a P4 Carbamate Replacement

Journal of medicinal chemistry, 2009-11, Vol.52 (22), p.7014-7028

2009

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The monoethyl ester of meconic acid is an active site inhibitor of HCV NS5B RNA-dependent RNA polymerase

Bioorganic & medicinal chemistry letters, 2004-06, Vol.14 (12), p.3257-3261

2004

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Routes to HIV-integrase inhibitors: efficient synthesis of bicyclic pyrimidones by ring expansion or amination at a benzylic position

Tetrahedron letters, 2009-01, Vol.50 (2), p.148-151

2009

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Problemas emocionales y de comportamiento en niños con discapacidad intelectual

Diversitas : perspectivas en psicología, 2018-01, Vol.14 (2), p.351-362

Coronel, Claudia Paola

2018

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AIRO Breast Cancer Group Best Clinical Practice 2022 Update

Tumori, 2022-07, Vol.108 (2_suppl), p.1-144

2022

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Novel P2–P4 macrocyclic inhibitors of HCV NS3/4A protease by P3 succinamide fragment depeptidization strategy

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (1), p.168-174

2010

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3-Aryl-2-Unsubstituted Indoles through the Palladium-Catalysed Reaction of o-Ethynyltrifluoroacetanilide with Aryl Iodides

Synlett, 1997-12, Vol.12 (12), p.1363-1366

1997

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Synthesis of Medium-Ring Nitrogen Heterocycles via Palladium-Catalyzed Heteroannulation of 1,2-Dienes

Journal of organic chemistry, 1998-10, Vol.63 (20), p.6859-6866

1998

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Palladium-Catalyzed Hydrovinylation of Vinyl Triflates with Alkynes An Approach to the Synthesis of 3-Vinylfuran-2(5H)-ones

European journal of organic chemistry, 1999-12, Vol.1999 (12), p.3305-3313

1999

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Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

Radiotherapy plus pembrolizumab for advanced urothelial carcinoma: results from the ARON-2 real-world study

Discovery of 4-((1-(1H-imidazol-2-yl)alkoxy)methyl)pyridines as a new class of Trypanosoma cruzi growth inhibitors

Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides

Ethyl N-(o-Ethynyl)malonanilide as a Useful Building Block for the Preparation of 3,4-Disubstituted-2(1H)-quinolones, 3,4-Disubstituted- and 2,3,4-Trisubstituted Quinolines

The Palladium-Catalyzed Hydroarylation and Hydrovinylation of Tertiary 3-(o-Acetoxyaryl)- and 3-(o-Benzoyloxyaryl)propynols − A Route to 4-Aryl- and 4-Vinyl-2,2-Dimethyl-3-chromenes

4,5-Dihydroxypyrimidine Carboxamides and N-Alkyl-5-hydroxypyrimidinone Carboxamides Are Potent, Selective HIV Integrase Inhibitors with Good Pharmacokinetic Profiles in Preclinical Species

A Convenient Synthesis of Nitrogen-Containing Heterocycles Bearing Amino Substituents from Heteroaryl Triflates

Electrosynthesis of Aromatic Aldehydes by Palladium-Catalyzed Carbonylation of Aryl Iodides in the Presence of Formic Acid

Discovery of α,γ-Diketo Acids as Potent Selective and Reversible Inhibitors of Hepatitis C Virus NS5b RNA-Dependent RNA Polymerase

Palladium-Catalyzed Cyclization of o-Alkynyltrifluoroacetanilides with Allyl Esters. A Regioselective Synthesis of 3-Allylindoles

Dihydroxypyrimidine-4-carboxamides as Novel Potent and Selective HIV Integrase Inhibitors

HCV NS5b RNA-Dependent RNA Polymerase Inhibitors: From α,γ-Diketoacids to 4,5-Dihydroxypyrimidine- or 3-Methyl-5- hydroxypyrimidinonecarboxylic Acids. Design and Synthesis

Discovery and Synthesis of HIV Integrase Inhibitors: Development of Potent and Orally Bioavailable N-Methyl Pyrimidones

4-Hydroxy-5-pyrrolinone-3-carboxamide HIV-1 integrase inhibitors

Novel Macrocyclic Inhibitors of Hepatitis C NS3/4A Protease Featuring a 2-Amino-1,3-thiazole as a P4 Carbamate Replacement

The monoethyl ester of meconic acid is an active site inhibitor of HCV NS5B RNA-dependent RNA polymerase

Prevention and management of radiotherapy-related toxicities in gynecological malignancies. Position paper on behalf of AIRO (Italian Association of Radiotherapy and Clinical Oncology)

Routes to HIV-integrase inhibitors: efficient synthesis of bicyclic pyrimidones by ring expansion or amination at a benzylic position

Problemas emocionales y de comportamiento en niños con discapacidad intelectual

AIRO Breast Cancer Group Best Clinical Practice 2022 Update

Novel P2–P4 macrocyclic inhibitors of HCV NS3/4A protease by P3 succinamide fragment depeptidization strategy

3-Aryl-2-Unsubstituted Indoles through the Palladium-Catalysed Reaction of o-Ethynyltrifluoroacetanilide with Aryl Iodides

Synthesis of Medium-Ring Nitrogen Heterocycles via Palladium-Catalyzed Heteroannulation of 1,2-Dienes

Palladium-Catalyzed Hydrovinylation of Vinyl Triflates with Alkynes An Approach to the Synthesis of 3-Vinylfuran-2(5H)-ones

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