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An improved zinc-finger nuclease architecture for highly specific genome editing

Nature biotechnology, 2007-07, Vol.25 (7), p.778-785

2007

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Gene-Specific Targeting of H3K9 Methylation Is Sufficient for Initiating Repression In Vivo

Current biology, 2002-12, Vol.12 (24), p.2159-2166

2002

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Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins

Nature (London), 1999-06, Vol.399 (6737), p.708-712

1999

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A Bacterial Two-Hybrid Selection System for Studying Protein-DNA and Protein-Protein Interactions

Proceedings of the National Academy of Sciences - PNAS, 2000-06, Vol.97 (13), p.7382-7387

2000

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Highly Specific Zinc Finger Proteins Obtained by Directed Domain Shuffling and Cell-Based Selection

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (21), p.12271-12276

2003

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A General Strategy for Selecting High-Affinity Zinc Finger Proteins for Diverse DNA Target Sites

Science (American Association for the Advancement of Science), 1997-01, Vol.275 (5300), p.657-661

1997

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Getting a Handhold on DNA: Design of Poly-Zinc Finger Proteins with Femtomolar Dissociation Constants

Proceedings of the National Academy of Sciences - PNAS, 1998-03, Vol.95 (6), p.2812-2817

1998

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Zinc-Finger Protein-Targeted Gene Regulation: Genomewide Single-Gene Specificity

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (21), p.11997-12002

2003

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Crystal Structure of a Five-Finger GLI-DNA Complex: New Perspectives on Zinc Fingers

Science (American Association for the Advancement of Science), 1993-09, Vol.261 (5129), p.1701-1707

1993

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Zinc finger-DNA recognition : crystal structure of a Zif268-DNA complex at 2.1 Å

Science (American Association for the Advancement of Science), 1991-05, Vol.252 (5007), p.809-817

1991

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High-resolution structures of variant Zif268–DNA complexes: implications for understanding zinc finger–DNA recognition

Structure (London), 1998-04, Vol.6 (4), p.451-464

1998

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Crystal structure of a paired domain-DNA complex at 2.5 å resolution reveals structural basis for pax developmental mutations

Cell, 1995-02, Vol.80 (4), p.639-650

1995

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Drug discovery with engineered zinc-finger proteins

Nature reviews. Drug discovery, 2003-05, Vol.2 (5), p.361-368

2003

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Structure of the Lambda Complex at 2.5 Å Resolution: Details of the Repressor-Operator Interactions

Science (American Association for the Advancement of Science), 1988-11, Vol.242 (4880), p.893-899

1988

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Allosteric Inhibition of Zinc-Finger Binding in the Major Groove of DNA by Minor-Groove Binding Ligands

Biochemistry (Easton), 2004-04, Vol.43 (13), p.3880-3890

2004

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Structure-Based Design of Transcription Factors

Science (American Association for the Advancement of Science), 1995-01, Vol.267 (5194), p.93-96

1995

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Tat Protein from Human Immunodeficiency Virus Forms a Metal-Linked Dimer

Science (American Association for the Advancement of Science), 1988-04, Vol.240 (4848), p.70-73

1988

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Engrailed (Gln50→Lys) homeodomain–DNA complex at 1.9 Å resolution: structural basis for enhanced affinity and altered specificity

Structure (London), 1997-08, Vol.5 (8), p.1047-1054

1997

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Transcription Factors: Structural Families and Principles of DNA Recognition

Annual review of biochemistry, 1992-01, Vol.61 (1), p.1053-1095

1992

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Dimerization of Zinc Fingers Mediated by Peptides Evolved in vitro from Random Sequences

Proceedings of the National Academy of Sciences - PNAS, 1999-08, Vol.96 (17), p.9568-9573

1999

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Zinc Finger Phage: Affinity Selection of Fingers with New DNA-Binding Specificities

Science (American Association for the Advancement of Science), 1994-02, Vol.263 (5147), p.671-673

1994

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Specificity by design

Nature biotechnology, 2006-08, Vol.24 (8), p.954-955, Article 954

Pabo, Carl O

2006

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Design of TATA Box-Binding Protein/Zinc Finger Fusions for Targeted Regulation of Gene Expression

Proceedings of the National Academy of Sciences - PNAS, 1997-04, Vol.94 (8), p.3616-3620

1997

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Constraints for Zinc Finger Linker Design as Inferred from X-ray Crystal Structure of Tandem Zif268–DNA Complexes

Journal of molecular biology, 2003-06, Vol.330 (1), p.1-7

2003

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Crystal structure of MyoD bHLH domain-DNA complex: Perspectives on DNA recognition and implications for transcriptional activation

Cell, 1994-05, Vol.77 (3), p.451-459

1994

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An improved zinc-finger nuclease architecture for highly specific genome editing

Gene-Specific Targeting of H3K9 Methylation Is Sufficient for Initiating Repression In Vivo

Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins

A Bacterial Two-Hybrid Selection System for Studying Protein-DNA and Protein-Protein Interactions

Highly Specific Zinc Finger Proteins Obtained by Directed Domain Shuffling and Cell-Based Selection

A General Strategy for Selecting High-Affinity Zinc Finger Proteins for Diverse DNA Target Sites

Getting a Handhold on DNA: Design of Poly-Zinc Finger Proteins with Femtomolar Dissociation Constants

Zinc-Finger Protein-Targeted Gene Regulation: Genomewide Single-Gene Specificity

Crystal Structure of a Five-Finger GLI-DNA Complex: New Perspectives on Zinc Fingers

Zinc finger-DNA recognition : crystal structure of a Zif268-DNA complex at 2.1 Å

High-resolution structures of variant Zif268–DNA complexes: implications for understanding zinc finger–DNA recognition

Crystal structure of a paired domain-DNA complex at 2.5 å resolution reveals structural basis for pax developmental mutations

Drug discovery with engineered zinc-finger proteins

Structure of the Lambda Complex at 2.5 Å Resolution: Details of the Repressor-Operator Interactions

Allosteric Inhibition of Zinc-Finger Binding in the Major Groove of DNA by Minor-Groove Binding Ligands

Structure-Based Design of Transcription Factors

Tat Protein from Human Immunodeficiency Virus Forms a Metal-Linked Dimer

Engrailed (Gln50→Lys) homeodomain–DNA complex at 1.9 Å resolution: structural basis for enhanced affinity and altered specificity

Transcription Factors: Structural Families and Principles of DNA Recognition

Dimerization of Zinc Fingers Mediated by Peptides Evolved in vitro from Random Sequences

Zinc Finger Phage: Affinity Selection of Fingers with New DNA-Binding Specificities

Specificity by design

Design of TATA Box-Binding Protein/Zinc Finger Fusions for Targeted Regulation of Gene Expression

Constraints for Zinc Finger Linker Design as Inferred from X-ray Crystal Structure of Tandem Zif268–DNA Complexes

Crystal structure of MyoD bHLH domain-DNA complex: Perspectives on DNA recognition and implications for transcriptional activation

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