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DNA damage response in cisplatin-induced nephrotoxicity

Archives of toxicology, 2015-12, Vol.89 (12), p.2197-2205

2015

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MicroRNA-687 Induced by Hypoxia-Inducible Factor-1 Targets Phosphatase and Tensin Homolog in Renal Ischemia-Reperfusion Injury

Journal of the American Society of Nephrology, 2015-07, Vol.26 (7), p.1588-1596

2015

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The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity

American Journal of Physiology - Renal Physiology, 2009-03, Vol.296 (3), p.F505-F511

2009

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ATR-Chk2 Signaling in p53 Activation and DNA Damage Response during Cisplatin-induced Apoptosis

The Journal of biological chemistry, 2008-03, Vol.283 (10), p.6572-6583

2008

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Checkpoint kinase 1 (Chk1)-short is a splice variant and endogenous inhibitor of Chk1 that regulates cell cycle and DNA damage checkpoints

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (1), p.197-202

2012

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Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (16), p.5231-5236

2015

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OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues

Cancer research (Chicago, Ill.), 2017-04, Vol.77 (8), p.2102-2111

2017

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A phosphotyrosine switch regulates organic cation transporters

Nature communications, 2016-03, Vol.7 (1), p.10880-10880, Article 10880

2016

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Cisplatin-Induced Renal Injury Is Independently Mediated by OCT2 and p53

Clinical cancer research, 2014-08, Vol.20 (15), p.4026-4035

2014

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Nek1 phosphorylates Von Hippel-Lindau tumor suppressor to promote its proteasomal degradation and ciliary destabilization

Cell cycle (Georgetown, Tex.), 2013-01, Vol.12 (1), p.166-171

2013

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Checkpoint kinase 1 in DNA damage response and cell cycle regulation

Cellular and molecular life sciences : CMLS, 2013-11, Vol.70 (21), p.4009-4021

2013

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Sibling rivalry in checkpoint control of cell cycle and DNA damage response

Cell cycle (Georgetown, Tex.), 2012-05, Vol.11 (10), p.1866-1867

2012

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DNA damage response in cisplatin-induced nephrotoxicity

Archives of toxicology, 2015-12, Vol.89 (12), p.2197-2205

2015

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Curtailing side effects in chemotherapy: a tale of PKCδ in cisplatin treatment

Oncotarget, 2012-01, Vol.3 (1), p.107-111

2012

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Caspase-mediated cleavage of ATM during cisplatin-induced tubular cell apoptosis: inactivation of its kinase activity toward p53

American journal of physiology. Renal physiology, 2006-12, Vol.291 (6), p.F1300-F1307

2006

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CCR 20th anniversary commentary: BMS-247550—microtubule stabilization as successful targeted therapy

Clinical cancer research, 2015-03, Vol.21 (6), p.1237-1239

2015

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hMSH2 Recruits ATR to DNA Damage Sites for Activation during DNA Damage-induced Apoptosis

The Journal of biological chemistry, 2011-03, Vol.286 (12), p.10411-10418

2011

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Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer

The Journal of clinical investigation, 2011-07, Vol.121 (7), p.2709-2722

2011

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Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia

The Journal of clinical investigation, 2018-01, Vol.128 (1), p.369-380

2018

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Abstract 5471: Identification of OAT1/OAT3 as contributors to cisplatin nephrotoxicity

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.5471-5471

2015

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Nek1 interacts with Ku80 to assist chromatin loading of replication factors and S-phase progression

Cell cycle (Georgetown, Tex.), 2013-08, Vol.12 (16), p.2608-2616

2013

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PKC-δ Promotes Renal Tubular Cell Apoptosis Associated with Proteinuria

Journal of the American Society of Nephrology, 2010-07, Vol.21 (7), p.1115-1124

2010

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Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia

The Journal of clinical investigation, 2018-01, Vol.128 (1), p.369

2018

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Systematic Evaluation of Tyrosine Kinase Inhibitors as OATP1B1 Substrates Using a Competitive Counterflow Screen

Cancer research communications, 2024-09, Vol.4 (9), p.2489-2497

2024

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Abstract 4415: Tyrosine phosphorylation is essential for OCT2 function and a target of inhibition by TKIs

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.4415-4415

2015

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DNA damage response in cisplatin-induced nephrotoxicity

MicroRNA-687 Induced by Hypoxia-Inducible Factor-1 Targets Phosphatase and Tensin Homolog in Renal Ischemia-Reperfusion Injury

The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity

ATR-Chk2 Signaling in p53 Activation and DNA Damage Response during Cisplatin-induced Apoptosis

Checkpoint kinase 1 (Chk1)-short is a splice variant and endogenous inhibitor of Chk1 that regulates cell cycle and DNA damage checkpoints

Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions

OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues

A phosphotyrosine switch regulates organic cation transporters

Cisplatin-Induced Renal Injury Is Independently Mediated by OCT2 and p53

Nek1 phosphorylates Von Hippel-Lindau tumor suppressor to promote its proteasomal degradation and ciliary destabilization

Checkpoint kinase 1 in DNA damage response and cell cycle regulation

Sibling rivalry in checkpoint control of cell cycle and DNA damage response

DNA damage response in cisplatin-induced nephrotoxicity

Curtailing side effects in chemotherapy: a tale of PKCδ in cisplatin treatment

Caspase-mediated cleavage of ATM during cisplatin-induced tubular cell apoptosis: inactivation of its kinase activity toward p53

CCR 20th anniversary commentary: BMS-247550—microtubule stabilization as successful targeted therapy

hMSH2 Recruits ATR to DNA Damage Sites for Activation during DNA Damage-induced Apoptosis

Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer

Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia

Abstract 5471: Identification of OAT1/OAT3 as contributors to cisplatin nephrotoxicity

Nek1 interacts with Ku80 to assist chromatin loading of replication factors and S-phase progression

PKC-δ Promotes Renal Tubular Cell Apoptosis Associated with Proteinuria

Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia

Systematic Evaluation of Tyrosine Kinase Inhibitors as OATP1B1 Substrates Using a Competitive Counterflow Screen

Abstract 4415: Tyrosine phosphorylation is essential for OCT2 function and a target of inhibition by TKIs

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