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A protocol for directly accessing geminal C-4 diarylated pyrazol-5(4 H )-ones via tandem C-H aryne insertion and their inceptive neurobiological evaluation

Organic & biomolecular chemistry, 2024-01, Vol.22 (4), p.714-719

2024

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Synthesis and evaluation of a novel quinoline-triazole analogs for antitubercular properties via molecular hybridization approach

Bioorganic & medicinal chemistry letters, 2019-10, Vol.29 (20), p.126671-126671, Article 126671

2019

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Total Synthesis of Marine-Derived Azole Resistant Antifungal Agent (–)-Melearoride A and Antibiotic (–)-PF1163B

SynOpen (2017), 2022-10, Vol.6 (4), p.227-237

2022

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Studies towards the total synthesis of cruentaren A and B: Stereoselective synthesis of fragments C1-C11, C12-C22 and C23-C28

Tetrahedron letters, 2017-07, Vol.58 (28), p.2685-2689

2017

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Stereoselective total synthesis and structural revision of the diacetylenic diol natural products strongylodiols H and I

Beilstein journal of organic chemistry, 2018-09, Vol.14 (1), p.2313-2320

2018

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Integrated multi-step continuous flow synthesis of daclatasvir without intermediate purification and solvent exchange

Reaction chemistry & engineering, 2020-11, Vol.5 (11), p.219-2114

2020

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A facile chiral pool synthesis of 9-epi-decarestrictine-D, decarestrictine-D and O

Tetrahedron: asymmetry, 2014-02, Vol.25 (3), p.203-211

2014

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Stereoselective total synthesis of the antiplasmodial resorcylic acid lactone paecilomycin F

ARKIVOC, 2015-10, Vol.2016 (2), p.123-136

2015

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A convergent total synthesis of resorcylic acid lactones zeaenol and cochliomycin A

Tetrahedron letters, 2022-05, Vol.97, p.153777, Article 153777

2022

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Total synthesis of antiviral drug, nirmatrelvir (PF-07321332)

Tetrahedron chem, 2022-12, Vol.4, p.100033-100033, Article 100033

2022

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A 2-oxa-spiro[5.4]decane scaffold displays neurotrophic, neurogenic and anti-neuroinflammatory activities with high potential for development as a versatile CNS therapeutic

Scientific reports, 2017-05, Vol.7 (1), p.1492-13, Article 1492

2017

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First stereoselective total synthesis of (−)-stagonolide A

Tetrahedron: asymmetry, 2010-01, Vol.21 (1), p.106-111

2010

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C-H modification of natural products: a minimalist enabling tactic for drug discovery, API processing and bioconjugation

Chemical communications (Cambridge, England), 2023-08, Vol.59 (62), p.9445-9456

2023

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Versatile Route to Benzoannulated Medium-Ring Carbocycles via Aryne Insertion into Cyclic 1,3-Diketones: Application to a Synthesis of Radermachol

Organic letters, 2016-06, Vol.18 (12), p.2832-2835

2016

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Natural products from the human microbiome: an emergent frontier in organic synthesis and drug discovery

Organic & biomolecular chemistry, 2024-05, Vol.22 (2), p.46-43

2024

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A Carbohydrate Approach for the First Total Synthesis of Cochliomycin C: Stereoselective Total Synthesis of Paecilomycin E, Paecilomycin F and 6′-epi-Cochliomycin C

European journal of organic chemistry, 2015-06, Vol.2015 (18), p.3983-3993

2015

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Domino Reactions through Recursive Anionic Cascades: The Advantageous Use of Nitronates

European journal of organic chemistry, 2022-11, Vol.2022 (42), p.n/a

2022

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A carbohydrate approach for the formal total synthesis of (-)-aspergillide C

Beilstein journal of organic chemistry, 2014-12, Vol.10 (1), p.3122-3126

2014

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A General Carbazole Synthesis via Stitching of Indole–Ynones with Nitromethanes: Application to Total Synthesis of Carbazomycin A, Calothrixin B, and Staurosporinone

Organic letters, 2019-05, Vol.21 (9), p.3372-3376

2019

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Nitromethane as a Carbanion Source for Domino Benzoannulation with Ynones: One‐Pot Synthesis of Polyfunctional Naphthalenes and a Total Synthesis of Macarpine

Angewandte Chemie International Edition, 2018-12, Vol.57 (51), p.16847-16851

International ed. in English, 2018

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Access to 2‑Alkyl/Aryl-4-(1H)‑Quinolones via Orthogonal “NH3” Insertion into o‑Haloaryl Ynones: Total Synthesis of Bioactive Pseudanes, Graveoline, Graveolinine, and Waltherione F

Organic letters, 2020-02, Vol.22 (4), p.1575-1579

2020

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Model studies towards paecilomycine A―C: exploring scaffold diversity through a key intramolecular Pauson―Khand reaction

Tetrahedron letters, 2011-04, Vol.52 (14), p.1663-1666

2011

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Spiroannulation of Oxindoles via Aryne and Alkyne Incorporation: Substituent-Diverted, Transition-Metal-Free, One-Pot Access to Spirooxindoles

Organic letters, 2017-06, Vol.19 (12), p.3119-3122

2017

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Stitching Ynones with Nitromethanes: Domino Synthesis of Functionally Enriched Benzofurans and Benzothiophenes

Journal of organic chemistry, 2021-09, Vol.86 (17), p.12093-12106

2021

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Stitching Oxindoles and Ynones in a Domino Process: Access to Spirooxindoles and Application to a Short Synthesis of Spindomycin B

Organic letters, 2017-11, Vol.19 (22), p.6152-6155

2017

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A protocol for directly accessing geminal C-4 diarylated pyrazol-5(4 H )-ones via tandem C-H aryne insertion and their inceptive neurobiological evaluation

Synthesis and evaluation of a novel quinoline-triazole analogs for antitubercular properties via molecular hybridization approach

Total Synthesis of Marine-Derived Azole Resistant Antifungal Agent (–)-Melearoride A and Antibiotic (–)-PF1163B

Studies towards the total synthesis of cruentaren A and B: Stereoselective synthesis of fragments C1-C11, C12-C22 and C23-C28

Stereoselective total synthesis and structural revision of the diacetylenic diol natural products strongylodiols H and I

Integrated multi-step continuous flow synthesis of daclatasvir without intermediate purification and solvent exchange

A facile chiral pool synthesis of 9-epi-decarestrictine-D, decarestrictine-D and O

Stereoselective total synthesis of the antiplasmodial resorcylic acid lactone paecilomycin F

A convergent total synthesis of resorcylic acid lactones zeaenol and cochliomycin A

Total synthesis of antiviral drug, nirmatrelvir (PF-07321332)

A 2-oxa-spiro[5.4]decane scaffold displays neurotrophic, neurogenic and anti-neuroinflammatory activities with high potential for development as a versatile CNS therapeutic

First stereoselective total synthesis of (−)-stagonolide A

C-H modification of natural products: a minimalist enabling tactic for drug discovery, API processing and bioconjugation

Versatile Route to Benzoannulated Medium-Ring Carbocycles via Aryne Insertion into Cyclic 1,3-Diketones: Application to a Synthesis of Radermachol

Natural products from the human microbiome: an emergent frontier in organic synthesis and drug discovery

A Carbohydrate Approach for the First Total Synthesis of Cochliomycin C: Stereoselective Total Synthesis of Paecilomycin E, Paecilomycin F and 6′-epi-Cochliomycin C

Domino Reactions through Recursive Anionic Cascades: The Advantageous Use of Nitronates

A carbohydrate approach for the formal total synthesis of (-)-aspergillide C

A General Carbazole Synthesis via Stitching of Indole–Ynones with Nitromethanes: Application to Total Synthesis of Carbazomycin A, Calothrixin B, and Staurosporinone

Nitromethane as a Carbanion Source for Domino Benzoannulation with Ynones: One‐Pot Synthesis of Polyfunctional Naphthalenes and a Total Synthesis of Macarpine

Access to 2‑Alkyl/Aryl-4-(1H)‑Quinolones via Orthogonal “NH3” Insertion into o‑Haloaryl Ynones: Total Synthesis of Bioactive Pseudanes, Graveoline, Graveolinine, and Waltherione F

Model studies towards paecilomycine A―C: exploring scaffold diversity through a key intramolecular Pauson―Khand reaction

Spiroannulation of Oxindoles via Aryne and Alkyne Incorporation: Substituent-Diverted, Transition-Metal-Free, One-Pot Access to Spirooxindoles

Stitching Ynones with Nitromethanes: Domino Synthesis of Functionally Enriched Benzofurans and Benzothiophenes

Stitching Oxindoles and Ynones in a Domino Process: Access to Spirooxindoles and Application to a Short Synthesis of Spindomycin B

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