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ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease domain: multipotential functions in cell-cell and cell-matrix interactions

The Journal of cell biology, 1995-10, Vol.131 (2), p.275-278

1995

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Why did the sperm cross the cumulus? To get to the oocyte. Functions of the sperm surface proteins PH-20 and fertilin in arriving at, and fusing with, the egg

Biology of reproduction, 1997-02, Vol.56 (2), p.320-327

1997

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Immunization of female cynomolgus macaques with a synthetic epitope of sperm-specific lactate dehydrogenase results in high antibody titers but does not reduce fertility

Molecular reproduction and development, 2002-06, Vol.62 (2), p.257-264

2002

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Penetration, Adhesion, and Fusion in Mammalian Sperm-Egg Interaction

Science (American Association for the Advancement of Science), 2002-06, Vol.296 (5576), p.2183-2185

2002

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A Hyaluronidase Activity of the Sperm Plasma Membrane Protein PH-20 Enables Sperm to Penetrate the Cumulus Cell Layer Surrounding the Egg

The Journal of cell biology, 1994-06, Vol.125 (5), p.1157-1163

1994

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Identification of a Binding Site in the Disintegrin Domain of Fertilin Required for Sperm-Egg Fusion

Proceedings of the National Academy of Sciences - PNAS, 1994-05, Vol.91 (10), p.4195-4198

1994

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The ADAM gene family: surface proteins with adhesion and protease activity

Trends in Genetics, 2000-02, Vol.16 (2), p.83-87

2000

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Sperm surface protein PH-20 is bifunctional: one activity is a hyaluronidase and a second, distinct activity is required in secondary sperm-zona binding

Biology of reproduction, 1996-07, Vol.55 (1), p.80-86

1996

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Sperm-egg fusion: events at the plasma membrane

Journal of cell science, 2004-12, Vol.117 (Pt 26), p.6269-6274

2004

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The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications

Proceedings of the National Academy of Sciences - PNAS, 1993-11, Vol.90 (22), p.10783-10787

1993

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Immunological response of female macaques to the PH-20 sperm protein following injection of recombinant proteins or synthesized peptides

Journal of reproductive immunology, 2002-03, Vol.54 (1), p.93-115

2002

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Identification and Purification of a Sperm Surface Protein with a Potential Role in Sperm-Egg Membrane Fusion

The Journal of cell biology, 1987-01, Vol.104 (1), p.141-149

1987

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Mechanism of infertility in male guinea pigs immunized with sperm PH-20

Biology of reproduction, 1997-05, Vol.56 (5), p.1133-1141

1997

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Analysis of Loss of Adhesive Function in Sperm Lacking Cyritestin or Fertilin β

Developmental biology, 2001-05, Vol.233 (1), p.204-213

2001

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Inhibition of monkey sperm hyaluronidase activity and heterologous cumulus penetration by flavonoids

Biology of reproduction, 1997-06, Vol.56 (6), p.1383-1389

1997

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Molecular Cloning of the Human and Monkey Sperm Surface Protein PH-20

Proceedings of the National Academy of Sciences - PNAS, 1993-11, Vol.90 (21), p.10071-10075

1993

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Localized Surface Antigens of Guinea Pig Sperm Migrate to New Regions Prior to Fertilization

The Journal of cell biology, 1984-11, Vol.99 (5), p.1634-1641

1984

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Location of the PH-20 protein on acrosome-intact and acrosome-reacted spermatozoa of cynomolgus macaques

Biology of reproduction, 1995-01, Vol.52 (1), p.105-114

1995

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Fertilization Defects in Sperm from Mice Lacking Fertilin β

Science (American Association for the Advancement of Science), 1998-09, Vol.281 (5384), p.1857-1859

1998

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cDNA Cloning Reveals the Molecular Structure of a Sperm Surface Protein, PH-20, Involved in Sperm-Egg Adhesion and the Wide Distribution of Its Gene among Mammals

The Journal of cell biology, 1990-12, Vol.111 (6), p.2939-2949

1990

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Structural relationship of sperm soluble hyaluronidase to the sperm membrane protein PH-20

Biology of reproduction, 1996-06, Vol.54 (6), p.1343-1349

1996

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A Role for the Migrating Sperm Surface Antigen PH-20 in Guinea Pig Sperm Binding to the Egg Zona Pellucida

The Journal of cell biology, 1985-12, Vol.101 (6), p.2239-2244

1985

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Reversible contraceptive effect of PH-20 immunization in male guinea pigs

Biology of reproduction, 1997-05, Vol.56 (5), p.1142-1146

1997

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A Role for the Disintegrin Domain of Cyritestin, a Sperm Surface Protein Belonging to the ADAM Family, in Mouse Sperm-Egg Plasma Membrane Adhesion and Fusion

The Journal of cell biology, 1997-04, Vol.137 (1), p.105-112

1997

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None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm–egg binding and fusion

Developmental biology, 2003-02, Vol.254 (2), p.226-237

2003

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ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease domain: multipotential functions in cell-cell and cell-matrix interactions

Why did the sperm cross the cumulus? To get to the oocyte. Functions of the sperm surface proteins PH-20 and fertilin in arriving at, and fusing with, the egg

Immunization of female cynomolgus macaques with a synthetic epitope of sperm-specific lactate dehydrogenase results in high antibody titers but does not reduce fertility

Penetration, Adhesion, and Fusion in Mammalian Sperm-Egg Interaction

A Hyaluronidase Activity of the Sperm Plasma Membrane Protein PH-20 Enables Sperm to Penetrate the Cumulus Cell Layer Surrounding the Egg

Identification of a Binding Site in the Disintegrin Domain of Fertilin Required for Sperm-Egg Fusion

The ADAM gene family: surface proteins with adhesion and protease activity

Sperm surface protein PH-20 is bifunctional: one activity is a hyaluronidase and a second, distinct activity is required in secondary sperm-zona binding

Sperm-egg fusion: events at the plasma membrane

The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications

Immunological response of female macaques to the PH-20 sperm protein following injection of recombinant proteins or synthesized peptides

Identification and Purification of a Sperm Surface Protein with a Potential Role in Sperm-Egg Membrane Fusion

Mechanism of infertility in male guinea pigs immunized with sperm PH-20

Analysis of Loss of Adhesive Function in Sperm Lacking Cyritestin or Fertilin β

Inhibition of monkey sperm hyaluronidase activity and heterologous cumulus penetration by flavonoids

Molecular Cloning of the Human and Monkey Sperm Surface Protein PH-20

Localized Surface Antigens of Guinea Pig Sperm Migrate to New Regions Prior to Fertilization

Location of the PH-20 protein on acrosome-intact and acrosome-reacted spermatozoa of cynomolgus macaques

Fertilization Defects in Sperm from Mice Lacking Fertilin β

cDNA Cloning Reveals the Molecular Structure of a Sperm Surface Protein, PH-20, Involved in Sperm-Egg Adhesion and the Wide Distribution of Its Gene among Mammals

Structural relationship of sperm soluble hyaluronidase to the sperm membrane protein PH-20

A Role for the Migrating Sperm Surface Antigen PH-20 in Guinea Pig Sperm Binding to the Egg Zona Pellucida

Reversible contraceptive effect of PH-20 immunization in male guinea pigs

A Role for the Disintegrin Domain of Cyritestin, a Sperm Surface Protein Belonging to the ADAM Family, in Mouse Sperm-Egg Plasma Membrane Adhesion and Fusion

None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm–egg binding and fusion

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