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The Emergence of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) as a Platform to Model Arrhythmogenic Diseases

International journal of molecular sciences, 2020-01, Vol.21 (2), p.657

2020

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A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes

eLife, 2023-09, Vol.12

2023

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Differential Distribution of Cardiac Ion Channel Expression as a Basis for Regional Specialization in Electrical Function

Circulation research, 2002-05, Vol.90 (9), p.939-950

2002

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The new antiarrhythmic drug vernakalant: ex vivo study of human atrial tissue from sinus rhythm and chronic atrial fibrillation

Cardiovascular research, 2013-04, Vol.98 (1), p.145-154

2013

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The Molecular Basis of High-Affinity Binding of the Antiarrhythmic Compound Vernakalant (RSD1235) to Kv1.5 Channels

Molecular pharmacology, 2007-12, Vol.72 (6), p.1522-1534

2007

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Comparison of electrophysiological and antiarrhythmic effects of vernakalant, ranolazine, and sotalol in canine pulmonary vein sleeve preparations

Heart rhythm, 2012-03, Vol.9 (3), p.422-429

2012

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Comparison of the In Vivo Hemodynamic Effects of the Antiarrhythmic Agents Vernakalant and Flecainide in a Rat Hindlimb Perfusion Model

Journal of cardiovascular pharmacology, 2011-04, Vol.57 (4), p.463-468

2011

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A mutational and modeling study of a binding pocket for IKs activators between KCNQ1 and KCNE1

Biophysical journal, 2023-02, Vol.122 (3), p.386a-387a

2023

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Effects of Electrical Stimulation on hiPSC-CM Responses to Classic Ion Channel Blockers

Toxicological sciences, 2020-04, Vol.174 (2), p.254-265

2020

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Kir2.4 and Kir2.1 K+ channel subunits co-assemble: a potential new contributor to inward rectifier current heterogeneity

The Journal of physiology, 2002-10, Vol.544 (2), p.337-349

2002

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A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes

eLife, 2023-09, Vol.12

2023

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Atrial Selective Effects of Intravenously Administered Vernakalant in Conscious Beagle Dogs

Journal of cardiovascular pharmacology, 2011-07, Vol.58 (1), p.49-55

2011

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Ranolazine improves diastolic function in spontaneously hypertensive rats

American journal of physiology. Heart and circulatory physiology, 2014-03, Vol.306 (6), p.H867-H881

2014

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CrossTalk proposal: The late sodium current is an important player in the development of diastolic heart failure (heart failure with a preserved ejection fraction)

The Journal of physiology, 2014-02, Vol.592 (3), p.411-414

2014

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Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) to model arrhythmogenic diseases

Journal of pharmacological and toxicological methods, 2018-09, Vol.93, p.118-118

2018

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A mutational and modeling study of a binding pocket for I Ks activators between KCNQ1 and KCNE1

Biophysical journal, 2023-02, Vol.122 (3S1), p.386a

2023

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Rebuttal from Marc Pourrier, Sarah Williams, Donald McAfee, Luiz Belardinelli and David Fedida

The Journal of physiology, 2014-02, Vol.592 (3), p.419-419

2014

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Rate-Dependent Effects of Vernakalant in the Isolated Non-Remodeled Canine Left Atria Are Primarily Due to Block of the Sodium Channel: Comparison With Ranolazine and dl-Sotalol

Circulation. Arrhythmia and electrophysiology, 2012-04, Vol.5 (2), p.400-408

2012

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Cardiac Ryanodine Receptor (Ryr2)-mediated Calcium Signals Specifically Promote Glucose Oxidation via Pyruvate Dehydrogenase

The Journal of biological chemistry, 2016-11, Vol.291 (45), p.23490-23505

2016

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Barium block of Kir2 and human cardiac inward rectifier currents : Evidence for subunit-heteromeric contribution to native currents

Cardiovascular research, 2003-08, Vol.59 (2), p.328-338

2003

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Comparison of ion channel distribution and expression in cardiomyocytes of canine pulmonary veins versus left atrium

Cardiovascular research, 2005, Vol.65 (1), p.104-116

2005

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KvLQT1 Modulates the Distribution and Biophysical Properties of HERG

The Journal of biological chemistry, 2004-01, Vol.279 (2), p.1233-1241

2004

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Vernakalant Blocks Kv4.3 Channels in The Open State Without Significant Modulation by KChIP2 Subunits

Biophysical journal, 2009-02, Vol.96 (3), p.178a-178a

2009

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Canine Ventricular KCNE2 Expression Resides Predominantly in Purkinje Fibers

Circulation research, 2003-08, Vol.93 (3), p.189-191

2003

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The interaction between delayed rectifier channel alpha-subunits does not involve hetero-tetramer formation

Naunyn-Schmiedeberg's archives of pharmacology, 2015-09, Vol.388 (9), p.973-981

2015

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The Emergence of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) as a Platform to Model Arrhythmogenic Diseases

A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes

Differential Distribution of Cardiac Ion Channel Expression as a Basis for Regional Specialization in Electrical Function

The new antiarrhythmic drug vernakalant: ex vivo study of human atrial tissue from sinus rhythm and chronic atrial fibrillation

The Molecular Basis of High-Affinity Binding of the Antiarrhythmic Compound Vernakalant (RSD1235) to Kv1.5 Channels

Comparison of electrophysiological and antiarrhythmic effects of vernakalant, ranolazine, and sotalol in canine pulmonary vein sleeve preparations

Comparison of the In Vivo Hemodynamic Effects of the Antiarrhythmic Agents Vernakalant and Flecainide in a Rat Hindlimb Perfusion Model

A mutational and modeling study of a binding pocket for IKs activators between KCNQ1 and KCNE1

Effects of Electrical Stimulation on hiPSC-CM Responses to Classic Ion Channel Blockers

Kir2.4 and Kir2.1 K+ channel subunits co-assemble: a potential new contributor to inward rectifier current heterogeneity

A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes

Atrial Selective Effects of Intravenously Administered Vernakalant in Conscious Beagle Dogs

Ranolazine improves diastolic function in spontaneously hypertensive rats

CrossTalk proposal: The late sodium current is an important player in the development of diastolic heart failure (heart failure with a preserved ejection fraction)

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) to model arrhythmogenic diseases

A mutational and modeling study of a binding pocket for I Ks activators between KCNQ1 and KCNE1

Rebuttal from Marc Pourrier, Sarah Williams, Donald McAfee, Luiz Belardinelli and David Fedida

Rate-Dependent Effects of Vernakalant in the Isolated Non-Remodeled Canine Left Atria Are Primarily Due to Block of the Sodium Channel: Comparison With Ranolazine and dl-Sotalol

Cardiac Ryanodine Receptor (Ryr2)-mediated Calcium Signals Specifically Promote Glucose Oxidation via Pyruvate Dehydrogenase

Barium block of Kir2 and human cardiac inward rectifier currents : Evidence for subunit-heteromeric contribution to native currents

Comparison of ion channel distribution and expression in cardiomyocytes of canine pulmonary veins versus left atrium

KvLQT1 Modulates the Distribution and Biophysical Properties of HERG

Vernakalant Blocks Kv4.3 Channels in The Open State Without Significant Modulation by KChIP2 Subunits

Canine Ventricular KCNE2 Expression Resides Predominantly in Purkinje Fibers

The interaction between delayed rectifier channel alpha-subunits does not involve hetero-tetramer formation

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